Filtyp
Föreliggande uppsats syftar till att, ur ett svensk perspektiv, belysa vad pantsättning av varumärken egentligen innebär. Möjligheterna till pantsättning av varumärken, och vad det innebär för en kreditgivare att ha pant i ett varumärke eller varumärkesansökan kommer att utredas. Inledningsvis behandlas den allmänna funktionen och syftet bakom panträtten. Härvid visas att panträttens viktigaste fu
One of the leading causes of severe childhood gastroenteritis are group A rotaviruses, and they have been found to be associated with ∼40% of the annual gastroenteritis-associated hospitalizations in young Danish children <5years of age (Fischer et al., 2011). In this study, we investigated the diversity of rotavirus strains circulating among young children <5years of age, presenting with gastroen
Background: Despite standard-of-care androgen-deprivation therapy and an increasing number of treatment options, the mortality rate for prostate cancer remains high. Progress to metastatic castration-resistant prostate cancer (mCRPC) necessitates additional treatments. Abiraterone acetate plus prednisone or prednisolone (AAP) prolongs survival in chemotherapy-naive and docetaxel-experienced patien
Disentangling biologically distinct subgroups of Alzheimer's disease (AD) may facilitate a deeper understanding of the neurobiology underlying clinical heterogeneity. We employed longitudinal [18F]FDG-PET standardized uptake value ratios (SUVRs) to map hypometabolism across cognitively-defined AD subgroups. Participants were 384 amyloid-positive individuals with an AD dementia diagnosis from ADNI
BACKGROUND. Endometrial carcinomas seem to carry a different prognosis depending on the presence or absence of concomitant complex atypical hyperplasia (hyperplasia). The molecular genetic profile of these two pathogenetic types, based on the genes reportedly mutated in these cancers, remains to be defined. Although microsatellite inability is reported in approximately 25% of endometrial carcinoma
UNLABELLED: Persistent CB1 cannabinoid receptor activity limits neurotransmitter release at various synapses throughout the brain. However, it is not fully understood how constitutively active CB1 receptors, tonic endocannabinoid signaling, and its regulation by multiple serine hydrolases contribute to the synapse-specific calibration of neurotransmitter release probability. To address this questi
An experiment was conducted to concentrate on the rainfall interception process of individual trees for four common species in Beijing, China, which included needle species (Platycladus orientalis and Pinus tabulaeformis) and broadleaf species (Quercus variabilis and Acer truncatum). Two types of interception storages, the maximum (Cmax) and the minimum interception storage (Cmin), were examined a
Background: At birth, infants' lungs are fluid-filled. For newborns to have a successful transition, this fluid must be replaced by air to enable effective breathing. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volu
Functional genomics methods are used to investigate the huge amount of information contained in genomes. Numerous experimental methods rely on the use of oligo- or polynucleotides. Nucleotide strand hybridization forms the underlying principle for these methods. For all these techniques, the probes should be unique for analyzed genes. In addition to being unique for the studied genes, the probes s
Vi spenderar en tredjedel av våra liv sovandes och sömn är en avgörande faktor för god hälsa och välbefinnande. Men det är även viktigt att erkänna sömnens komplexitet, eftersom det är flera faktorer som kan påverka sömnen. Både biologiska, kontextuella och psykosociala faktorer har inverkan på ungdomarnas sömn. Otillräcklig sömn, sömnproblem och symptom på insomni är vanligt hos ungdomar. SömnlösInsufficient sleep, sleep problems and insomnia are common in adolescents, and insomnia and insufficient sleep are public health concerns that can impact adolescents’ mental and physical health. There are several different treatments for sleep problems and insomnia, and there is a great focus on the problem when it has already arisen. However, since this is a public health problem, it is important
Experiments were carried out to analyze the function of cysteine residues at amino acid positions 506 (cI), 550 (cII), 573 (cIII), and 610 (cIV), in dimerization and/or disulfide linkage of human cytomegalovirus (HCMV) glycoprotein B (gB). Single c-codons or pairs were substituted in the gB sequence of constructs which were used for transfection and selection of stable transfectants. Analysis of g
Background: Unwarranted variation in care practice and outcomes has gained attention and inter-hospital comparisons are increasingly being used to highlight and understand differences between hospitals. Adjustment for case mix is a prerequisite for meaningful comparisons between hospitals with different patient populations. The objective of this study was to identify and quantify maternal characte
Extended AbstractIn this paper, I examine why the Gallipoli War narrative has become increasingly important in the discourse of the JDP (Justice and Development Party) governments over the last two decades, and how this visible tendency is related to the construction and protection of the neoliberal government in Turkey. I frame the discussion by utilizing Loïc Wacquant’s concept of the “centaur s
Reinvestment in water and wastewater (WW) facilities is a challenge for Swedish water utilities. Nationwide, 4% of 184 organizations meet the requirements for a sustainable WW facility status according to the sustainability index (SI), the Swedish benchmark system. Eleven Swedish municipal WW organizations that had improved the status of their facilities were examined and are presented as good lea
Aims: To identify the best strategy to achieve complete revascularization (CR) in patients with ST-elevation myocardial infarction (STEMI) and multi-vessel disease (MVD). Methods and results: We systematically reviewed the literature for randomized controlled trials (RCTs) comparing IRA-only PCI and CR guided by angiography or fractional flow reserve (FFR) in MVD-STEMI. Both frequentist (classical
A receptor upregulated on regulatory T cells, in this work referred to as receptor X, is a candidate target for cancer treatment. An antibody targeting this receptor could potentially suppress and/or deplete regulatory T cells and hereby lead to activation of effector T cells and tumor regression. In this work fully human scFv fragments targeting receptor X were isolated from a phage display libra
Kollektivtrafiken skapar nytta för både privatpersoner och samhället i stort, och bidrar med bemötandet av en rad samhällsmål relaterade till miljö, transportsäkerhet och tillgängliga transportlösningar. För att tillåta fortsatt utveckling av en konkurrenskraftig kollektivtrafik i Sverige, kartläggs och analyseras trender, utmaningar och utvecklingsmöjligheter. Kollektivtrafiken utmanas av bland Public transportation systems provide accessible transport options for all citizens, reducing environmental impact by lowering emissions, improving traffic safety, and promoting social equity and public health. It plays a crucial role in achieving national goals related to sustainable development and climate change mitigation. However, in its aim to increase competitiveness to other modes of trans
Amelogenin is a protein which has been found to have many interesting properties. Its biological function is a key part in organizing the crystals of the enamel and it has been found to have a clinical use for periodontal regeneration. Its self-assembling properties also makes amelogenin a suitable material for the fabrication of biomaterials. The aim of this project is to investigate the possibil
