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Cyanogenic Potential of Roasted Cassava (Manihot esculenta Crantz) roots Rale from Inhambane Province, Mozambique

Roasted cassava roots flour is part of a common meal in Africa, it is known as rale in Mozambique. Fifty six samples of rale were collected from homes and markets in Inhambane Province, Mozambique, for cyanogenic potential (CNp) analyses. The names of cassava varieties used for preparing the rale samples could be determined in the home-collected samples, three varieties were recorded. Xinhembwe va

Inflammation in Parkinson’s Disease and Experimental Neural Transplantation. Role of Cellular Responses, Cytokines and Immunosuppression in Graft Rejection.

Abstract: Parkinson’s disease (PD) is a common neurodegenerative disorder. There is no proven protection, but many treatments can partially improve symptoms. The disease is caused by monogenetic mechanisms in very few cases, but for the majority of patients the etiology is unknown. Epidemiological studies have identified a potential role for inflammation. The thesis investigates inflammation and i

Arterial roads do not have to be big, ugly and difficult for non-motorists

The objective of this paper is to describe the evaluation and effects of a major reconstruction of an arterial street in Eskilstuna, a medium sized Swedish town. The aim of the reconstruction was to minimize the barrier effects of the arterial street and by that create a stronger connection between the town center, on one side of the street, and the town-river, on the other; but also to create gen

”Dom kunde väl få lov att sitta ner och dricka kaffe och prata ibland…” – De äldres syn på hemtjänstinsatserna, relationen till personalen och hjälpen från närstående

The aim of the study is to examine what kind of help the elderly get, if the elderly get the help they want, how the staff treat them and how much contact they have with others than the home-help staff. Further the study looks on how the well-being of the elderly was affected by the relationship with the home-help staff and contact with other people than the home-help staff. To conduct the study i

Some novel aspects of DNA physical and chemical gels

DNA chemical and physical networks have been investigated with respect to their stability and swelling, and rheological properties. Chemical networks were prepared by cross-linking DNA with ethylene glycol diglycidyl ether (EGDE), and physical networks by association with cationic polymers. Both types of gels display strong elastic properties and have a shear thinning behaviour. Addition of cation

Ectoparasitism in marsh tits: costs and functional explanations

Among hole-nesting birds, the blood-sucking hen flea is a common parasite affecting both nestlings and parents. By adding fleas to marsh tit (Parus palustris) nests, I aimed to investigate the effect of fleas on nestling growth rate and parental effort as well as evaluating a potential mechanism by which fleas affect nestlings (i.e., resting metabolic rate; RMR). Nestlings from flea-infested brood

Insulin-like Growth Factor System: functional role and regulation in carcinomas

The insulin-like growth factor (IGF) system demonstrates numerous actions during neoplastic growth and is therefore an interesting target with potential clinical implications. While numerous studies have established important roles of the IGF system in regulating cellular growth and survival of several tumor forms, very limited reports exist regarding its role in renal cell carcinoma (RCC). The ai

Hydrophobic interaction chromatography of fibroblast proteoglycans

We have investigated the hydrophobic properties of human skin fibroblast proteoglycans and related material by affinity chromatography on Octyl-Sepharose CL-4B in 4 M guanidinium hydrochloride (GdnHCl). Proteoglycans and related material could be separated into non-, medium and highly hydrophobic forms by elution with gradients of Triton X-100 in 4 M Gdn HCl. The non-hydrophobic material included

Dissolved oxygen controller based on on-line measurements of ammonium combining feed-forward and feedback

As the largest single energy-consuming component in most biological wastewater treatment systems, control of aeration is of great interest seen from an energy savings point of view. This paper suggests a simple way of using on-line ammonium measurements to control aeration in a pre-denitrification plant by controlling the dissolved oxygen setpoint. The controller works primarily by feed-forward ba

Experimental granulomatous alveolitis in rat. Effect of antigen manipulation, smoke exposure and route of administration

When Sephadex beads (0.45mg/kg b.w) are instilled intratracheally into rats, a granulomatous alveolitis with giant cell formation and fibrosis occurs. Moreover, the events in the alveolar region are paralleled by an eosinophil-dominated peribronchitis/bronchiolitis and perivasculitis. Bronchoalveolar lavage (BAL) shows a very distinct feature with an early pronounced neutrophil increase, followed

Pharmacy Regulation in Sweden. A New Institutional Economic Perspective

Popular Abstract in Swedish Syftet med denna avhandling är att analysera och förklara den institutionella förändringen vad gäller läkemedelsförsäljning i Sverige. Avhandlingens bidrag är studier av denna specifika institutionella utveckling där nyinstitutionell ekonomisk teori har använts för att undersöka drivkrafterna. Avhandlingen består av tre artiklar. Syftet med den första artikeln är att beThe aim of this thesis is to analyze and to explain the institutional change in the provision of pharmaceuticals in Sweden. The thesis’ contribution is studies of this specific institutional development. New Institutional Economic theory is used to scrutinize the driving forces of this development. The thesis consist of three papers. The purpose of the first paper is to discuss and to analyze the

Modelling flow routing in permafrost landscapes with TWI : an evaluation against site-specific wetness measurements

In northern peatlands the thawing of permafrost increasing the active layer depth and changing the hydrology may lead to feedbacks in the climate system through changes in the biogeochemistry of carbon. We are examining this association on the Stordalen peatland complex in subarctic Sweden by analyzing a DEM derived from LiDAR-data and the calculated TWI. The DEM, with a spatial resolution of 1 m,

Continuous lipid bilayers derived from cell membranes for spatial molecular manipulation

Progress with respect to enrichment and separation of native membrane components in complex lipid environments, such as native cell membranes, has so far been very limited. The reason for the slow progress can be related to the lack of efficient means to generate continuous and laterally fluid supported lipid bilayers (SLBs) made from real cell membranes. We show in this work how the edge of a hyd

Long-Term Increase in Hibernating Bats in Swedish Mines - Effect of Global Warming?

We present the result of bat winter censuses in three old mines in southern Sweden from 1980 until present (2017). The Taberg and Kleva mines, each with about 1.5 km of accessible passages, have winter populations of 517 and 132 bats, respectively (maximum counts) belonging to six species, the highest numbers known in underground sites in Sweden. Ädelfors is less extensive and has fewer individual

Meaning of home and health dynamics among younger older people in Sweden

Research has shown that positive evaluations of home are important for very old people’s health, well-being and independence in daily life. The rationale for the present study derives from our survey study findings, confirming such associations also in a younger cohort (N = 371). The purpose of this study was to further increase the understanding of the dynamics of meaning of home and health among

Familial upper aerodigestive tract cancers : incidence trends, familial clustering and subsequent cancers

Familial risks in upper aerodigestive tract cancer have been assessed mainly through case-control studies based on reported but not medically verified cancers in family members. The nationwide Swedish Family-Cancer Database was used to describe the incidence trends for all subsites of upper aerodigestive tract cancer and to calculate standardized incidence ratios (SIRs) and 95% confidence interval

Structural changes in model oxide catalysts studied by operando XAFS

Bridging the pressure gap between surface science studies and industrial processes requires a combination of well-studied reactions, model systems as catalysts, and advanced techniques capable of detecting structural changes under realistic pressure conditions. Observations from such studies provide helpful insight into the present phases of the gas-surface boundary and transitions that happen dur

Large-scale systematic review support for guideline development in diabetes precision medicine

Background: Involving librarians as team members can lead to better quality in reviews. To improve their search results, an international diabetes project involved two medical librarians in a large-scale project planning of a series of systematic reviews for clinical guidelines in diabetes precision medicine. Case Presentation: The precision diabetes project was divided into teams. Four diabetes m