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Objectives: To evaluate the ability of the Assessment of Different NEoplasias in the adneXa (ADNEX) model and the International Ovarian Tumour Analysis (IOTA) two-step strategy to predict malignancy in adnexal masses detected in an outpatient low-risk setting, and to estimate the risk of complications in masses with benign ultrasound morphology managed using clinical and ultrasound follow-up. Meth

The placement of gambling problems within the Hierarchical Taxonomy of Psychopathology (HiTOP) framework, which organizes psychopathology alongside broad overarching symptom spectra, is unclear. With the objective to identify associations between gambling problems and the internalizing, externalizing, and thought disorder spectra of the HiTOP, we distributed an online survey to a sample of 1005 Sw

CONTEXT: Minipuberty, a period of a transient activation of the hypothalamic-pituitary-gonadal (HPG) axis in both sexes, enables evaluation of gonadal function in infants suspected of hypogonadism. However, female minipuberty remains poorly elucidated. OBJECTIVE: We aimed to establish continuous reference ranges for the most commonly used reproductive hormones and to evaluate the dynamics of the H

Background: Patients have an estimated mortality of 15–20% within the first year following myocardial infarction and one in four patients who survive myocardial infarction will develop heart failure, severely reducing quality of life and increasing the risk of long-term mortality. We aimed to establish the accuracy of an artificial neural network (ANN) algorithm in predicting 1-year mortality and

BACKGROUND: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has improved the survival in selected colorectal cancer patients with peritoneal metastases. In these patients, the risk of a low anastomosis is sometimes diminished through the creation of a colostomy. Currently, the morbidity and mortality associated with the reversal of the colostomy in this population

Background: Clubfeet are typically shorter than normal feet. This study aimed first to describe the development of foot length in a consecutive series of children with congenital clubfoot and second to relate foot length to development of relapse and motion quality. Methods: Foot length was measured every 6 months in 72 consecutive children with congenital clubfoot (29 bilateral) aged from 2 to 7

According to guidelines, total ischemic time for homografts at processing must be kept short to avoid degeneration. Many homografts are discarded due to practical inability to finish all steps from procurement to cryopreservation within the time limit. Although, several studies have shown that homografts with prolonged ischemic time show adequate quality and performance. Twenty aortic and 12 pulmo

Achieving high follow-up rates after smoking cessation interventions (SCIs) is a general challenge. The aim of this study was to identify preferences among patients and therapists for improving follow-up rates and to assess smoking status at 6 months among patients lost to follow-up. From the Danish STOPbase for Tobacco and Nicotine, which collects data on SCI across health care, 20 representative

AIM: To compare two identification methods for risky drinking in primary health care centres (PHCs).METHODS: Sixteen PHCs from three Swedish counties were randomized into strands: consultation-based early identification (CEI) or systematic screening early identification (SS). Measurements took place at baseline and during two intervention periods. Patients filled in questionnaires including gender

Background: Somatic and germline genetic alterations are significant drivers of cancer. Increasing integration of new technologies which profile these alterations requires timely, equitable and high-quality genetic counselling to facilitate accurate diagnoses and informed decision-making by patients and their families in preventive and clinical settings. This article aims to provide an overview of

Background. Over five billion people worldwide lack access to safe and affordable surgery and anesthesia care when required. There is a critical unmet need for surgical care, especially in low-income and middle-income countries (LMICs). The shortage of surgical providers is one of the most influential barriers to receiving surgical care, and the maldistribution is aggravated by doctors emigrating

Introduction and Aims: Up to 80% of adolescents have experienced trauma and one-in-seven suffer from post­ traumatic stress disorder (PTSD). For 50% of these adoles­cents, the course of their illness is further complicated by a co-occurring substance use disorder (SUD). Despite high rates of comorbidity, treatment options remain sparse and there is limited understanding of the clinical profile ass

Objective: For many years, functional tricuspid regurgitation (FTR) was considered negligible after treatment of left-sided heart valve surgery. The aim of the present network meta-analysis is to summarize the results of four approaches to establish the possible gold standard. Methods: A systematic search was performed to identify all publications reporting the outcomes of four approaches for FTR,

AbstractBackground and purpose: The need for knee replacement revision arises from a combination of patient, prosthesis and surgeon factors. Registry data can help study these relationships. Pooling data from multiple registries may increase both reliability and generalizability. The study aim was to gain a multi-national overview of knee replacement revision, to inform best-practice and improve o

Twenty-three lines from a mutagenized Bangladeshi BARI Gom-25 wheat population that included previously identified salt-tolerant lines, and the BARI Gom-25 control variety, were cultivated in a drip-irrigated salinity test field at Salt Farm Texel, Netherlands, to assess their performance during salt stress in European climatic conditions. Lines were tested at irrigation salinity levels of 1, 4, 8