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Aortic valve replacement in patients older than 85 years: outcomes and the effect on their quality of life

PURPOSE: The aim of this study was to investigate the outcome of aortic valve replacement (AVR) and the effect on quality of life in patients aged over 85 who had symptomatic aortic stenosis. METHODS: We performed a retrospective analysis of 21 patients, aged 85-91 years (mean age 86.5), who underwent AVR, 10 of whom underwent concomitant coronary artery bypass grafting (CABG) between 1989 and 199

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Rome in Sweden? The Catholic Offensive in Ecumenical-National Context Since World War II, ecumenical principles have been used as historical measures. This has led to re-interpretations of historical events and to alterations of sources, for example the letters and diaries by Elisabeth Hesselblad, the renewer of St. Birgitta’s order. In the literature on the Swedish Archbishop Nathan Söderblom, th

Three-dimensional T1 quantification techniques for assessment of cartilage quality using dGEMRIC

Popular Abstract in Swedish Artros är en av de vanligaste kroniska sjukdomarna och en av de främsta orsakerna till funktionshinder för människor världen över. Artros angriper ofta knä- och höftlederna och bryter ner det brosk som finns där. För den som drabbats av artros tar förloppet ofta många år, med successivt ökande smärtor och rörelsesvårigheter. Ofta upptäcks dessutom inte sjukdomen förrän Osteoarthritis (OA) is a common chronic disease and one of the major global causes for functional disabilities. The disease is characterized by loss and degradation of cartilage, commonly affecting the knees and hips. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a previously presented method for identification of early OA using magnetic resonance imaging (MRI). By quantifying the T1 p

Impacts of Regional Climate Change on Swedish Forests: An Evaluation Using Process-based Regional Ecosystem Modelling Approach

The overall aim of this thesis was to provide a representative estimate of the potential impacts of climate change and increased atmospheric CO2 concentrations on Swedish forest ecosystems and the key ecosystem services they provide. In order to achieve this task, fi rst LPJ-GUESS, a process-based regional ecosystem modelling framework, was applied to explore how possible shifts in climatic zones

The appropriate use of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel

Introduction Given the safety issues of nonsteroidal anti-inflammatory drugs (NSAID) and the robustness of guidelines, making treatment choices in daily clinical practice is increasingly difficult. This study aimed systematically to analyse the opinions of a multidisciplinary European expert panel on the appropriateness of different NSAID, with or without the use of a proton pump inhibitor (PPI),

Students’ experiences and perceptions of good teaching practice

Through in-depth interviews, students’ experiences and perceptions of good teaching practice in literature and physics during one school year were investigated in eight upper secondary classes of the first, second and third years in Greece. Students’ feelings of joy, pleasure and personal meaning in the teaching and learning situation were in focus of the research. Three main and interconnected as

Impact of environmental exposure on concrete strength in highway bridges in Uganda

Deterioration of concrete structures is a worldwide problem. Environmental exposure is known to affect concrete strength in structures. While moisture affects rebound values by lowering them, carbonation does the opposite. The aim of the study was to determine the in-situ concrete strength of three bridge elements, namely, pier, abutment and deck and evaluate the environmental conditions such as m

Comparison of genotyping methods by application to Salmonella livingstone strains associated with an outbreak of human salmonellosis

During 2000 and 2001, an outbreak of human salmonellosis occurred in Sweden and Norway, caused by Salmonella livingstone. In this study, the genotypic differences between three strains obtained from food sources during the outbreak, two human strains and 27 more or less unrelated strains were analysed, using the three methods; automated ribotyping, pulsed field get electrophoresis (PFGE) and rando

Contributions of other brain pathologies in dementia with lewy bodies.

The clinical picture with its pathological correlate was analysed in 16 patients fulfilling consensus criteria for dementia with Lewy bodies (DLB). The cases were part of a larger cohort (n = 200) of patients within a prospective longitudinal study of dementing disorders. Six cases exhibited not only Lewy bodies (LBs) but also other brain pathologies such as Alzheimer changes, multiple infarcts or

Dedifferentiation of serous ovarian cancer from cystic to solid tumors is associated with increased expression of mRNA for urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1)

The plasminogen activating system is involved in tumor growth and metastasis by degradation of extracellular matrix, and modulation of cell adhesion and migration. Benign and well-differentiated malignant ovarian tumors present as cystic lesions with preserved glandular morphology, whereas poorly differentiated tumors and metastases are solid with characteristic absence of glandular morphology. We

Effects of IL-2 treatment on different compartments of the irradiated rat lung analysed by bronchoalveolar lavage and lung tissue morphology

In recent years, interleukin-2 (IL-2) has been used as an immunomodulatory agent in the treatment of various malignant tumours. However, this treatment has been limited by serious side-effects, including toxic reactions in the lung. The effects of IL-2 treatment on inflammatory cell populations in the normal and irradiated rat lung were investigated in this study. IL-2 was continuously administere

Diversity of soil mite communities when managing plant communities on set-aside arable land

When restoring former agricultural land to more low-nutrient input ecosystems, the establishment of a plant community can be enhanced by sowing desirable species. In this study our aim was to determine whether management of the plant community influences the microarthropod community. We carried out a field experiment in three European countries on set-aside arable land and determined soil mites fr

Analysis of heterocyclic amines in food products: interlaboratory studies

A feasibility study and two interlaboratory exercises on the determination of selected heterocyclic amines (HAs) in beef extract, organised in the framework of a European project, are presented. The aim of these exercises was to improve the quality of the laboratories and to evaluate the performance of a standardised analytical method and also the methods currently used by each of the participants

Modeling to Predict Factor VIII Levels Associated with Zero Bleeds in Patients with Severe Hemophilia A Initiated on Tertiary Prophylaxis

Background: Factor VIII (FVIII) trough levels > 1 IU/dL in patients with severe hemophilia A receiving regular prophylaxis may optimize bleed protection. Objectives: In this post hoc analysis of patients receiving tertiary prophylaxis for approximately 1 year, the relationship between estimated FVIII levels and reported bleeds was investigated to predict the potential for zero bleeds. Methods: Six

Effects of storage conditions on degradation of chlorophyll and emulsifying capacity of thylakoid powders produced by different drying methods

Thylakoid membranes isolated from spinach have previously been shown to inhibit lipase/co-lipase and prolong satiety in vivo. There is a need to develop thylakoid products that not only have the desired characteristics and functionality after processing, but also are stable and provide equivalent effect on appetite over the promised shelf life. The aim of the present study was therefore to evaluat

Bussbolags miljöpåverkan - Samspelet mellan ett bussbolags miljöarbete och kommunernas krav vid offentlig upphandling

Bussbolags miljöpåverkan - Hur kan verksamheter och kommun arbeta för en effektivare minskning av miljöpåverkan? Miljöpåverkan innebär all förändring ett företag utgör som påverkar miljön och verksamheten ett bussbolag driver innebär i de flesta fall stor negativ miljöpåverkan. Genom ett företags egna initiativ till ett förbättrat miljöarbete kan miljöpåverkan minska men även kommuner kan bidra tiThis study is on behalf of Röke Buss and aims to identify the significant environmental impacts of the company as well as to review the environmental requirements posted by public buyers. The study is divided in two sections; the first section is a document analysis that analyses RFQs (request of quotation) of school bus services from the municipalities within Scania to identify its environmental

Varför bör kvinnorepresentationen öka? En textstudie av den interna debatten inom tre politiska kvinnoförbund under sjuttiotalet

When it comes to political representation, all over the world women almost always make up a minority of representatives in the legislative bodies. The Scandinavian countries in general and Sweden in particular have though been exceptions to this rule with, when compared to other countries, a rather high percentage of women in elected positions. This development took off in the seventies: during th

Injury severity prediction of cyclist crashes using random forests and random parameters logit models

Cycling provides numerous benefits to individuals and to society but the burden of road traffic injuries and fatalities is disproportionately sustained by cyclists. Without awareness of the contributory factors of cyclist death and injury, the capability to implement context-specific and appropriate measures is severely limited. In this paper, we investigated the effects of the characteristics rel

Growth differentiation factor-15 improves long-term mortality risk prediction beyond the GRACE 2.0 score after acute coronary syndrome

This study examined whether Growth Differentiation Factor-15 (GDF-15) and echocardiographic measures of systolic left ventricular function improve intermediate- and long-term mortality risk prediction beyond the guideline-endorsed GRACE 2.0 score after Acute Coronary Syndrome (ACS). 751 ACS patients were included. GDF-15, left ventricular ejection fraction (LVEF), and global longitudinal strain (G