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Synthesis and characterisation of new PCsp3P-supported nickel complexes

The coordination behaviour of the aliphatic pincer ligand cis-1,3-bis-((di-tert-butylphosphino)methyl) cyclohexane with NiCl2 and NiBr2 was studied. Reflux in toluene afforded cyclometalated, tridentate PCsp3P pincer complexes, that were characterised by elemental analysis and NMR spectroscopy; the solid state structures were determined by X-ray diffraction showing an unusually long Ni-Br bond in

Deep sea records from the southeast Labrador Sea: Ocean circulation changes and ice-rafting events during the last 160,000 years

[1] Results from two deep sea cores from northeast of Newfoundland at 1251 and 2527 m water depth, respectively, indicate that during the time period from 160,000 to 10,000 years BP, ice rafting events in the Labrador Sea were accompanied by rapid variations in deep and surface water circulation. Twelve ice-rafting events occurred, each coinciding with high concentrations of detrital carbonate and

Transient aggregation and stable dimerization induced by introducing an Alzheimer sequence into a water-soluble protein

Transient contacts between denatured polypeptide chains are likely to play an important part in the initial stages of protein aggregation and fibrillation. To analyze the nature of such contacts, we have carried out a protein engineering study of the 102-residue protein U1A, which aggregates transiently in the wild-type form during refolding from the guanidinium chloride-denatured state. We have p

Adsorption of cationic cellulose derivative/anionic surfactant complexes onto solid surfaces. II. Hydrophobized silica surfaces

The effect of the anionic surfactant SDS (sodium dodecyl sulfate) on the adsorption behavior of cationic hydroxyethyl cellulose (Polymer JR-400) and hydrophobically modified cationic cellulose (Quatrisoft LM-200) at hydrophobized silica has been investigated by null ellipsometry and compared with the previous data for adsorption onto hydrophilic silica surfaces. The adsorbed amount of LM-200 is fo

Combining landslide and contaminant risk: a preliminary assessment

The aim of this paper is to highlight a not yet recognized hazard for mass failure (landslides) of contaminated soils into rivers and to provide an understanding of important interactions of such events. A first effort to investigate the problem is made focusing on the south eastern part of the Gota A"lv river valley, in Sweden, by combining geographical information on potentially contaminated sit

Pattern recognition methods in evaluation of the structure of the laboratory data biominerals, antioxidant enzymes, selected biochemical parameters, and pulmonary function of welders

A wide set of biochemical and spirometrical parameters was applied to a group of 41 welders. The obtained parameters were analyzed by the pattern recognition method: principal-components analysis (PCA) and mutual contribution analysis (MCA). The aim of the investigation was to find out which of 23 parameters had an influence on the pulmonological indices of COPD. It was found that PCA gave a subst

The recent decline of the Starling Sturnus vulgaris population in Sweden: a 22-year nest-box study / Den sentida nedgången av starens Sturnus vulgaris bestånd i Sverige: en 22-årig holkstudie

This study reports the changes in number of breeding Starlings Sturnus vulgaris as recorded in seventeen areas distributed over all Sweden in 1981-2002. The number of breeding attempts declined by about fifty percent, consistent with the general decline observed in the Swedish Breeding Bird Survey. In no area was a long-term increase observed. There was no consistent geographical pattern; areas wi

A comparative study of ordinary and mineralised Portland cement clinker from two different production units Part I: Composition and hydration of the clinkers

Portland cement clinkers from two production units were investigated; Plant 1: ordinary clinker (P1) and clinker mineralised with CaF2+CaSO4 (P1m); Plant 2: ordinary clinker (P2) and two clinkers mineralised with CaF2+CaSO4 (P2m, low SO3 and P2m', high SO3). The chemical composition of the clinkers was determined by X-ray fluorescence, ICP analysis, titration (free lime) and ion selective electrod

Importance of the evolutionarily conserved glycine residue in the N-terminal region of cystatin C (Gly-11) for cysteine endopeptidase inhibition

Human cystatin C variants in which the evolutionarily conserved Gly-11 residue has been replaced by residues with positively charged (Arg), negatively charged (Glu), bulky hydrophobic (Trp), or small (Ser or Ala) side-chains have been produced by site-directed mutagenesis and expression in Escherichia coli. The five variants were isolated and structurally verified. Their inhibitory properties were

Macrophage Activation and AP-1 in Atherosclerosis

High levels of very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease. Hypertriglyceridemia is generally associated with an increased expression of inflammatory makers and inflammation is thought to contribute to atherosclerosis and its complications. The present investigation was aimed at providing

Studies of moisture and alkalinity in self-levelling flooring compounds

Popular Abstract in Swedish

Under de senaste decennierna har innemiljön och dess relation till hälsa rönt ett allt större intresse. En viktig aspekt i detta sammanhang har varit kopplingen mellan fukt i byggnader och hälsa.

Cementbaserade material innehåller ofta överskottsvatten ("byggfukt") när de gjuts då detta är nödvändigt för deras arbetbarhet och flytegenskaper. Förutom det höga vat

In recent decades there has been an increasing interest in the indoor environment and its connections with public health. One important topic discussed has been the relation between the moisture in buildings and health.

Cementitious materials, when cast, contain excess water since this is necessary for workability and for flow properties. The pore solutions in cementitious materials, besid

Population-Based Study of Treatment Guided by Tumor Marker Decline in Patients With Metastatic Nonseminomatous Germ Cell Tumor: A Report From the Swedish-Norwegian Testicular Cancer Group.

PURPOSE From 1995 to 2003, 603 adult patients from Sweden and Norway with metastatic testicular nonseminomatous germ cell tumor (NSGCT) were included prospectively in a population-based protocol with strict guidelines for staging, treatment, and follow-up. Patients with extragonadal primary tumor or previous treatment for contralateral testicular tumor were excluded. The basic strategy was to indi

Costs and quality of life of patients with multiple sclerosis in Europe

Objective: To assess overall resource consumption, work capacity and quality of life of patients with multiple sclerosis in nine European countries. Methods: Information on resource consumption related to multiple sclerosis, informal care by relatives, productivity losses and overall quality of life (utility) was collected with a standardised pre-tested questionnaire from 13186 patients enrolled i

Absorbed Dose Determination and Characteristics of Degraded Electron Beams: Application to Intraoperative Radiation Therapy

Popular Abstract in Swedish Intraoperativ strålbehandling (IORT) innebär att en hög engångsstråldos ges direkt under operation till den kirurgiskt frilagda tumören och/eller kvarvarande tumörrester. Den vanligaste typen av strålning som används vid denna behandlingsform är elektronstrålning från konventionella medicinska linjäracceleratorer. Det krävs dock att ett speciellt applikatorsystem finns The aim of this work was to quantify limitations of and uncertainties in commonly used dosimetric techniques for relative absorbed dose determination in degraded electron beams, such as those encountered in intraoperative radiation therapy (IORT) and small-electron-field radiotherapy. Three different detector types were investigated with regard to measurements of output factors and relative absorb

Start point to savings – Better load demand analysis in commercial buildings

Existing installations and energy systems in most commercial buildings could be used in a more efficient way to provide savings – both in terms of energy and load demand. The key for effective operation is a thorough and detailed analysis of energy use patterns that creates essential baseline for energy savings and the development of demand response (DR) strategies. The knowledge of energy deman

Physical activity and regional bone mass

Popular Abstract in Swedish Under de senaste decennierna har osteoporos (benskörhet) erhållit allt större uppmärksamhet eftersom allt fler individer drabbas av åkomman. Osteoporos är en sjukdom som ökar med stigande ålder och framför allt drabbar kvinnor. Sjukdomen leder till ökad risk för fraktur (benbrott) och antalet osteoporosrelaterade frakturer har ökat markant under senaste halvan av 1900-tThis thesis considers the effect of physical activity on bone mass in weight-loaded and unloaded regions of the skeleton. Bone mass was measured by Dual X-ray Absorptiometry (DXA) and by Quantitative Ultrasound (QUS). In a cross-sectional study 67 male soccer-players, on different levels of the Swedish national league, were compared with 24 male controls. No differences were demonstrated between s

Addressing smoking during pregnancy:The challenge to start from the woman's view

Popular Abstract in Swedish Kvinnor känner till att det är riskabelt att röka när de blir gravida. Trots detta så slutar bara omkring hälften i Sverige och var tredje kvinna i många andra länder att röka när de blir gravida. Syftet i den här avhandlingen har varit att studera varför det är så svårt för gravida kvinnor att sluta röka. Problemområdet har studerats med olika utgångspunkter; gravida k

Axeheads and fire - the transformation of wealth

Massive destruction of flint and stone artefacts by fire has been found at two sites in south-eastern Scania, the southernmost county of Sweden. At the site of Svartskylle, dated to the Early Funnel-Necked Beaker Culture (TRB) at about 3400 cal. BC, fragments showed that several thin-butted flint axeheads as well as a small number of thin-bladed axeheads had been heavily fragmented by fire. During

Mineralogical and geochemical characterization of the concotto artefacts from firing places of Longola protohistoric settlement (Naples)

A set of concotto samples, a type of fired mixture of various raw materials, coming from firing place of the perifiuvial protohistoric site of Longola (Campania region, southern Italy) was characterized by means of a multi-analytical approach, i.e. polarized light optical microscopy (OM), X-ray powder diffraction (XRD), scanning electron microscopy and energy dispersive spectrometry (SEM-EDS), X-r

Appearance of remodelled and dendritic cell-rich alveolar-lymphoid interfaces provides a structural basis for increased alveolar antigen uptake in chronic obstructive pulmonary disease.

RATIONALE: The alveolar pathology in chronic obstructive pulmonary disease (COPD) involves antigen-driven immune events. However, the induction sites of alveolar adaptive immune responses have remained poorly investigated. OBJECTIVES: To explore the hypothesis that interfaces between the alveolar lumen and lymphoid aggregates (LAs) provide a structural basis for increased alveolar antigen uptake i