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Background: Disturbance in the oropharyngeal microbiota is common in hospitalized patients and contributes to the development of nosocomial pneumonia. Lactiplantibacillus plantarum 299 and 299v (Lp299 and Lp299v) are probiotic bacteria with beneficial effects on the human microbiome. Aim: To investigate how Lp299 and Lp299v affect the growth of nosocomial oropharyngeal pathogens in vitro and to ev
Objective. Patients with ANCA-associated vasculitides (AAV) exhibit higher rates of malignancy than the general population. We assessed whether the cancer risk is increased in a well-characterized population-based cohort of AAV in southern Sweden, followed for a median time of 8 years. Methods. With case record review, the outcomes and malignancy development in a cohort of 195 patients with AAV [g
Hemorrhagic cystitis (HC) is a debilitating complication following allogenic hematopoietic cell transplantation (HCT). HLA disparity and T-cell depletion have been implicated as risk factors for HC. However, reports on the incidence and risk factors for HC in ex vivo T-cell depleted haploidentical HCT (haploHCT) in children are lacking. We studied 96 haploHCT procedures performed in 83 children be
Under början av förra seklet skedde en formlig reception av tysk processrätt genom Ernst Kallenbergs verk Svensk Civilprocessrätt i två band. Således kom läran om processföremålet genom 1942 års processreform att läggas till grund för utformningen av den svenska rättegångsbalken (RB). Läran om processföremålet innebär att saken är den omtvistade rättigheten i det bakom-liggande rättsförhållande soAt the turn of the last century, a formal reception of German procedural law took place through Ernst Kallenberg’s work ’Svensk Civilprocessrätt’ in two volumes. Thereby, the German doctrine on the essence of the claim formed the basis for the Swedish Code of Procedure, rättegångsbalken (RB), through the procedural reform of 1942. The doctrine on the essence of the claim holds that the matter cont
Kelp forests are among the most productive ecosystems on Earth, releasing detritus year-round through direct blade erosion, storm-induced detachment, wave breakage, seasonal shedding, as well as indirect urchin grazing. Fragmental kelp detritus is transported from the euphotic zone to deeper parts of the ocean such as fjords, where decomposition rates are very low and detritus may contribute to lo
According to guidelines, total ischemic time for homografts at processing must be kept short to avoid degeneration. Many homografts are discarded due to practical inability to finish all steps from procurement to cryopreservation within the time limit. Although, several studies have shown that homografts with prolonged ischemic time show adequate quality and performance. Twenty aortic and 12 pulmo
AIM: To compare two identification methods for risky drinking in primary health care centres (PHCs).METHODS: Sixteen PHCs from three Swedish counties were randomized into strands: consultation-based early identification (CEI) or systematic screening early identification (SS). Measurements took place at baseline and during two intervention periods. Patients filled in questionnaires including gender
Achieving high follow-up rates after smoking cessation interventions (SCIs) is a general challenge. The aim of this study was to identify preferences among patients and therapists for improving follow-up rates and to assess smoking status at 6 months among patients lost to follow-up. From the Danish STOPbase for Tobacco and Nicotine, which collects data on SCI across health care, 20 representative
Ensuring close control of critical quality attributes (CQAs), such as post-translational modifications (PTMs), in therapeutic monoclonal antibodies (mAbs) is essential for maintaining function and batch homogeneity in large-scale production. Common PTMs include deamidation, fragmentation, oxidation, charge variants, and glycosylations. This study aimed to evaluate CQA variations and correlate the
Information for external reviewer and examination committee members at the Faculty of Social Sciences, Lund University Page 1 of 8 Faculty Office PM Reg. No. U 2025/596 2023-06-30, revised 2025-09-17 Information for external reviewer and examination committee members at the Faculty of Social Sciences, Lund University This guide explains the procedures of defence of doctoral thesis as well as the r
Page 1 of 8 Faculty Office PM Reg. No. U 2025/596 2023-06-30, revised 2025-09-17 Information for external reviewer and examination committee members at the Faculty of Social Sciences, Lund University This guide explains the procedures of defence of doctoral thesis as well as the roles of external reviewer and member of the examining committee at the Faculty of Social Sciences. For reference, the s
Effects of size and charge of anionic nanoclays on their interactions with bacteria-mimicking lipid membranes, bacterial lipopolysaccharide (LPS), and Gram-negative bacteria were investigated using ellipsometry, dynamic light scattering, ζ-potential measurements, and confocal microscopy combined with Live/Dead staining. Based on particle size and charge density, three different anionic hectorite n
We present a neural network autoencoder structure that is able to extract essential latent spectral features from observed spectra and then reconstruct a spectrum from those features. Because of the training with a set of unpeculiar spectra, the network is able to reproduce a spectrum of high signal-to-noise ratio that does not show any spectral peculiarities, even if they are present in an observ
Among plants, gender dimorphism occurs in about 10% of all angiosperms and more than 50% of all moss taxa, with dwarf males (DM) found exclusively in some unisexual mosses. In this study, we explore the role of male dwarfism as a reproductive strategy in the widespread acrocarpous moss Dicranum scoparium, which has facultative male dwarfism, having both dwarf males (DMs) and normal-sized males (NM
This study examined whether Growth Differentiation Factor-15 (GDF-15) and echocardiographic measures of systolic left ventricular function improve intermediate- and long-term mortality risk prediction beyond the guideline-endorsed GRACE 2.0 score after Acute Coronary Syndrome (ACS). 751 ACS patients were included. GDF-15, left ventricular ejection fraction (LVEF), and global longitudinal strain (G
Background: Women with Turner syndrome (TS) have an increased risk of aortic dissection. The current recommended cutoff to prevent aortic dissection in TS is an aortic size index (ASI) of ≥2.5 cm/m2. This study estimated which aortic size had the best predictive value for the risk of aortic dissection, and whether adjusting for body size improved risk prediction. Methods: A prospective, observatio
Sewage sludge amendment of soils leads to an increase in soil fertility, but may induce heterogeneities not initially present in the soil. Spatial variation of soil organic carbon (C) and nitrogen (N) was studied in a heavy clay soil after a sewage sludge application and NPK-treatment (nitrogen, phosphorus, and potassium) using geostatistical approaches. In total, 314 soil samples were taken on tw
To report the association of autoimmune polyglandular syndrome type 1 (APS1) with cone dystrophy in a large Saudi family. This is a Retrospective chart review and prospective genetic testing and ophthalmic examination of a large multiplex consanguineous family. Genetic testing was performed on 14 family members, seven of whom had detailed ophthalmic examinations. Medical history, ocular history an
