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Popular Abstract in Swedish Under de senaste decennierna har osteoporos (benskörhet) erhållit allt större uppmärksamhet eftersom allt fler individer drabbas av åkomman. Osteoporos är en sjukdom som ökar med stigande ålder och framför allt drabbar kvinnor. Sjukdomen leder till ökad risk för fraktur (benbrott) och antalet osteoporosrelaterade frakturer har ökat markant under senaste halvan av 1900-tThis thesis considers the effect of physical activity on bone mass in weight-loaded and unloaded regions of the skeleton. Bone mass was measured by Dual X-ray Absorptiometry (DXA) and by Quantitative Ultrasound (QUS). In a cross-sectional study 67 male soccer-players, on different levels of the Swedish national league, were compared with 24 male controls. No differences were demonstrated between s

Objectives: To compare the pharmacodynamic effects of a pharmacokinetically enhanced formulation of amoxicillin 2000 mg twice daily, with amoxicillin 875 mg twice daily, 875 mg three times daily and 500 mg three times daily against Streptococcus pneumoniae with different susceptibility to amoxicillin in an in vitro kinetic model. Methods: Strains of S. pneumoniae with amoxicillin MICs of 1, 2, 4 a

A simple calorimetric method for determination of amylose content in starch is reported. Starches were heated in the presence of two common surfactants, viz., sodium dodecyl sulphate (SDS) and cetyltrimethylammonium bromide (CTAB), and the enthalpies of melting of the amylose-surfactant complexes were determined using Modulated Differential Scanning Calorimetry (MDSC). A large number of native sta

Objective: To evaluate the psychometric properties of the French KOOS physical function (KOOS-PS) and HOOS physical function (HOOS-PS), specifically its feasibility, reliability, construct validity, and responsiveness. Methods: Consecutive outpatients consulting for primary knee or hip osteoarthritis (OA) in a rheumatology department were included. During the initial assessment, patients were aske

We present here a genome-wide map of abnormalities found in diagnostic samples from 45 adults and adolescents with acute lymphoblastic leukemia (ALL). A 500K SNP array analysis uncovered frequent genetic abnormalities, with cryptic deletions constituting half of the detected changes, implying that microdeletions are a characteristic feature of this malignancy. Importantly, the pattern of deletions

The extraction procedure for analysis of the raffinose family oligosaccharides (RFOs) in blanched leguminous vine peas was optimized. For this purpose, 25 pea samples from different cultivars and of different maturity were chosen at random. The effect of blanching was also studied in four cultivars. The yield of oligosaccharides was almost double on average when extracted with 50% ethanol as compa

The objective of this study was to analyze the accumulated effects of leaching in two test roads were municipal solid waste incineration (MSWI) bottom ash and aggregate from a railway embankment, respectively, were used as subbase aggregates. Solid samples from the subbase and the subgrade were collected in trenches, which were excavated perpendicular to the road extension. The samples were analyz

We have previously shown that selective heavy meromyosin (HMM) adsorption to predefined regions of nanostructured polymer resist surfaces may be used to produce a nanostructured in vitro motility assay. However, actomyosin function was of lower quality than on conventional nitrocellulose films. We have therefore studied actomyosin function on differently derivatized glass surfaces with the aim to

To investigate the effect of exposure to tobacco smoke (TS) on the development of irradiation-induced pneumonitis in rats, five groups of animals were investigated including controls (C), tobacco smoke exposed (S), irradiated (RNS) and irradiated and tobacco smoke exposed (RS). An additional group (RS/NS) was exposed to tobacco before irradiation but not afterwards. Rats were exposed to diluted ma

We sought to determine whether the COMT val158met polymorphism (rs4680) is associated with delusions and hallucinations in people with dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). A total of 218 individuals, recruited from centres in Norway, Sweden and the UK were included in this study; 121 with clinically or neuropathologically diagnosed DLB/PDD and 97 age-matched, cog

Purpose: Eddy current induced velocity offsets are of concern for accuracy in cardiovascular magnetic resonance (CMR) volume flow quantification. However, currently known theoretical aspects of eddy current behavior have not led to effective guidelines for the optimization of flow quantification sequences. This study is aimed at identifying correlations between protocol parameters and the resultin

Background: Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, hypertension, obesity, physical inactivity, alcohol and poor diet towards risk of premature death. Methods: We analysed data from 264,906 European adults from the EPIC prospective

I tidigare forskning om krig presenteras ofta ensidiga bilder av fenomenen krigsvåld, offerskap och försoning. Denna bok utgår från berättelser av överlevande efter kriget i Bosnien under 1990-talet. Syftet är att analysera hur de intervjuade beskriver dessa fenomen samt vilka diskursiva mönster som framträder i konstruktionen av begreppen ”offer” och ”förövare”. Mina frågeställningar är: Hur beskThis book analyzes verbally depicted experiences of survivors from the war in Bosnia and Herzegovina. One purpose to describe how the actors portray the social phenomenon of “war violence” “victimhood” and “reconciliation”, and the second aim is to analyze discursive patterns that emerges in the creation of the terms “victim” and “perpetrator”. My research questions are: (1) How do the interviewee

Cultural and creative activities are today described as central to regional and urban development by politicians and governments. Creative city policies are often aiming at economic benefits for the city itself, and there are normative purposes with many research studies as well as projects undertaken (Eckardt 2005; Markusen and Gadwa 2010; Kovacs 2011). Creative city policy is often oriented towa

Antiserum against bovine retinal S-antigen, a soluble protein (MW = 50 kDa) thought to be involved in phototransduction, was used in an immunohistochemical and immunochemical study of vertebrate eyes and pineal systems and invertebrate photoreceptor organs. Positive reactions, not seen with antiserum preabsorbed with highly purified S-antigen, were observed in planarian and starfish ocelli; scallo

Objective: To describe beliefs about health and illness among foreign-born people with diabetic foot ulcers that might affect selfreported self-care and health-care seeking and to study whether there are dissimilarities related to origin. Method: Qualitative descriptive study. Semi-structured interviews with people aged 38-86 years; 13 born in European and 13 in non-European countries (all except

Purpose: Enterolactone (ENL) is formed in the human gut after consumption of lignans, has estrogenic properties, and has been associated with risk of prostate cancer. We examined the association between plasma ENL levels and prostate cancer in a nested case–control study within the population-based Malmö Diet and Cancer cohort. We also examined the association between plasma ENL and dietary and li