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Background: Women with adverse pregnancy outcomes may have higher subsequent risk of chronic kidney disease, but the long-term independent risks and potential causality are unclear. Objective: This study aimed to determine long-term risks of chronic kidney disease associated with 5 major adverse pregnancy outcomes in a large population-based cohort, and to assess for familial confounding using co-
Background: Children whose parents have alcohol use problems are at an increased risk of several negative consequences, such as poor school performance, an earlier onset of substance use, and poor mental health. Many would benefit from support programs, but the figures reveal that only a small proportion is reached by existing support. Digital interventions can provide readily accessible support a
Amyloid fibrils have been implicated in the pathogenesis of several neurodegenerative diseases, the most prevalent example being Alzheimer's disease (AD). Despite the prevalence of AD, relatively little is known about the structure of the associated amyloid fibrils. This has motivated our studies of fibril structures, extended here to the familial Arctic mutant of Aβ1-42, E22G-Aβ1-42. We found E22
Late effects of polio (LEoP), a chronic progressive neuromuscular condition that affects people who have had polio earlier in life. LEoP manifests with new symptoms such as muscle weakness, fatigue, and pain, and can also have consequences for an individual’s level of activity and participation. People with LEoP can benefit from comprehensive rehabilitation, with focus on enabling activity and par
BACKGROUND: Cell blocks (CBs) are widely used for biomarker analyses such as immunostaining. Although immunohistochemistry on formalin-fixed paraffin-embedded tissues is standardized, there are multiple preparation methods and fixatives for cytology. Our objective was to investigate the effect of different common fixatives on the immunoreactivity of pleural effusion CBs with metastatic lung adenoc
Heart failure (HF) is associated with high mortality, decreased quality of life, and places a heavy burden on healthcare resources. Numerous HF patients are diagnosed without a conclusive echocardiogram and are lacking appropriate pharmacotherapy. The majority of HF studies in Sweden are based on hospital registries that may not represent the entirety of the HF patient population. This thesis exam
Purpose: Iron deficiency anemia is common in people with inflammatory bowel disease (IBD), causing deterioration in quality of life, which can be reversed by treatment that increases iron stores and hemoglobin levels. The present post hoc analyses estimate health state utility values for patients with IBD after treatment with ferric derisomaltose or ferric carboxymaltose and evaluate the health do
In December 2019, China reported the first cases of the coronavirus disease 2019 (COVID-19). This disease, caused by the severe acute respiratory syndrome–related coronavirus 2 (SARS-CoV-2), has developed into a pandemic. To date, it has resulted in ~9 million confirmed cases and caused almost 500 000 related deaths worldwide. Unequivocally, the COVID-19 pandemic is the gravest health and socioeco
An active line of research in proof complexity over the last decade has been the study of proof space and trade-offs between size and space. Such questions were originally motivated by practical SAT solving, but have also led to the development of new theoretical concepts in proof complexity of intrinsic interest and to results establishing nontrivial relations between space and other proof comple
BACKGROUND: The Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) trial was a non-inferiority trial that compared percutaneous coronary intervention (PCI) using first-generation paclitaxel-eluting stents with coronary artery bypass grafting (CABG) in patients with de-novo three-vessel and left main coronary artery disease, and reported results up to 5 years. We now report 10-year all-cau
Gliomas are the most common intracranial primary tumors, for which very few therapeutic options are available. The most malignant subtype is the glioblastoma, a disease associated with a 5-year survival rate lower than 5%. Given that research in glycobiology continues highlighting the role of glycans in tumor cell biology, it offers an interesting niche for the search of new therapeutic targets. I
Degradation of extracellular matrix, is a prerequisite for processes like tumor invasion and angiogenesis. Numerous studies indicate that plasminogen activation, initiated by u-PA, is a key process in malignant tumor growth. The expression of u-PA as well as its receptor is increased in malignant ovarian tumors. Additionally, u-PA stimulates signal transduction leading to cell proliferation and mi
Rationale and aims: The Quality of Dyadic Relationships is a self-assessment scale used to evaluate various aspects of relationship quality. Psychometric evaluation by the developers of the instrument has led to a nontested amended version. Further psychometric testing is thus warranted, and the aim of this study was to evaluate homogeneity, construct validity (in terms of concurrent, discriminant
Background: Although alcohol use disorder (AUD) runs strongly within families, studies examining the impact of rearing environment, unconfounded by genetic effects, are rare and, to date, contradictory. We here seek to conduct such a study using an adoptive co-sib control design. Methods: Defining high-risk as having 3/41 biological parent with an externalizing syndrome (AUD, drug abuse or crime),
Background: In chronic obstructive pulmonary disease (COPD), both the time needed for patients to gain symptom improvement with long-acting bronchodilator therapy and whether an early response is predictive of a sustained response is unknown. This study aimed to investigate how quickly meaningful symptom responses are seen in patients with COPD with bronchodilator therapy and whether these respons
In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a prostate cancer risk allele, we evaluated the association between HOXB13 germline mutations and breast cancer risk in a previous study consisting of 3,270 familial non-BRCA1/2 breast ca
Today, every new building is constructed with the ambition of it having a very low energy demand or even being completely neutral with regard to supply and demand over a year. In modern low energy or nearly zero energy residential buildings like these, the behaviour of the occupants becomes increasingly more significant in terms of the energy performance of the building. Occupants who are present
The article focuses on individual students’ studies within a practicebased MFA program in visual art in Sweden. The individual cases of studying that form the basis for this investigation, represent a particularly autonomous and self-directed kind of studying. Although the kind of autonomy and selfdirection varies between visual art programs, as well as its extent, these are largely qualities that
Business and Human Rights Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Progr
https://rwi.lu.se/news-categories/business-and-human-rights/ - 2026-07-23
SIMRISH.â,UN grglgg4gu. larrsskap: Skåne Eärad: Jäi¡restacl Soeken; Slmríshann Upptechringsår: 19+1 M. 762+. Upptech.at av. Wal.ter He1.1n Aclress¡ Berättat av: Fru Elma Petersson Föd¿l år 1877 i Sa]']-erup. Foto av Sjögrens oo A,W.Peterssons ganrla kõpmansgåxd s¡ 1-7. livet i köpnansgårclen. so 4. Ägg vid påsk¡ s. 5. J¡¡l-klappar. s. 5 ,6 . Majstang. s. 6. Utflykter. s. 6. 51å katten ur turanan.
https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/stadstrad/Simrishamn.pdf - 2026-07-23
