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Extended chronologies of aqueous alteration in the CM2 carbonaceous chondrites : Evidence from carbonates in Queen Alexandra Range 93005

The Antarctic CM2 carbonaceous chondrite QUE 93005 contains four compositionally distinct carbonates, namely breunnerite, calcite, dolomite and a Ca-poor dolomite. These carbonates can form monomineralic grains, or may be intergrown as bimineralic grains consisting of dolomite plus breunnerite and dolomite plus calcite, or polymineralic grains containing an intergrowth of breunnerite, Ca-poor dolo

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Diagnostic reference levels are the main and the most effective tools of optimization of the radiation protection of patients from medical exposure. Diagnostic reference levels should be established based on theresults of dedicated dose surveys, allowing evaluating typical patient dose distributions in a selected dose quantity for the selected X-ray examinations. The aim of the current study was t

Time to Peak Glucose and Peak C-Peptide During the Progression to Type 1 Diabetes in the Diabetes Prevention Trial and TrialNet Cohorts

OBJECTIVE: To assess the progression of type 1 diabetes using time to peak glucose or C-peptide during oral glucose tolerance tests (OGTTs) in autoantibody-positive relatives of people with type 1 diabetes. RESEARCH DESIGN AND METHODS: We examined 2-h OGTTs of participants in the Diabetes Prevention Trial Type 1 (DPT-1) and TrialNet Pathway to Prevention (PTP) studies. We included 706 DPT-1 partic

Applicability of polygenic risk scores in endometriosis clinical presentation

Background: Risk prediction is an essential part of preventative medicine and in recent years genomic information has become an interesting factor in risk models. Polygenic risk scores (PRS) combine the effect of many genetic variations into a single score which has been shown to have predictive value for many diseases. This study aimed to investigate the association between PRS for endometriosis

Evolution of a cluster of innate immune genes (beta-defensins) along the ancestral lines of chicken and zebra finch

BACKGROUND: Avian beta-defensins (AvBDs) represent a group of innate immune genes with broad antimicrobial activity. Within the chicken genome, previous work identified 14 AvBDs in a cluster on chromosome three. The release of a second bird genome, the zebra finch, allows us to study the comparative evolutionary history of these gene clusters between from two species that shared a common ancestor

Terahertz Spectroscopic Analysis of Lactose in Infant Formula : Implications for Detection and Quantification

Lactose plays a significant role in daily lives as a constituent of various food and pharmaceutical products. Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requir

Dataset of dust mass accumulation rates for the loess-palaeosol sequences from the Carpathian Basin

In this article, a dataset of age-depth modelling data, sedimentation rates and dust mass accumulation rates (MAR) from four loess-palaeosol sequences from the Carpathian Basin is presented. The dataset is related to the article “Detailed luminescence dating of dust mass accumulation rates over the last two glacial-interglacial cycles from the Irig loess-palaeosol sequence, Carpathian Basin”, publ

Local Treatment of Unresectable Colorectal Liver Metastases : Results of a Randomized Phase II Trial

Background: Tumor ablation is often employed for unresectable colorectal liver metastases. However, no survival benefit has ever been demonstrated in prospective randomized studies. Here, we investigate the long-term benefits of such an aggressive approach. Methods: In this randomized phase II trial, 119 patients with unresectable colorectal liver metastases (n < 10 and no extrahepatic disease) re

Agile practices in global software engineering – a systematic map

This paper presents the results of systematically reviewing the current research literature on the use of agile practices and lean software development in global software engineering (GSE). The primary purpose is to highlight under which circumstances they have been applied efficiently. Some common terms related to agile practices (e.g. scrum, extreme programming) were considered in formulating th

Rasch Analysis of the Norwegian Version of the Occupational Balance Questionnaire in a Sample of Occupational Therapy Students

Background. Recently, the Occupational Balance Questionnaire developed in Sweden was translated into Norwegian. No studies to date have examined the measurement properties of the Norwegian version of this questionnaire. Aim. The study is aimed at examining the psychometric properties of the Norwegian version of the Occupational Balance Questionnaire, the OBQ11-N. Methods. Along with sociodemograph

Tumor‐associated humoral cytotoxicity in patients with acute myelogenous leukemia before and after chemotherapy

Sera of eight unselected adult patients with acute myelogenous leukemia obtained before and after chemotherapy were repeatedly tested for specific complement‐dependent cytotoxicity against autochthonous peripheral white blood cells from the acute leukemia stage and from the remission stage, respectively. Complement‐dependent cytotoxicity against white blood cells from the acute leukemia stage was

The association between carotid-femoral pulse-wave velocity and lung function in the Swedish CArdioPulmonary bioImage study (SCAPIS) cohort

Background: Arterial ageing is characterised by degradation of elastic fibres and increased stiffness of elastic arteries. Although low lung function and arterial stiffness are strongly related to age, the association between lung function and arterial ageing has not been widely explored. We used a large population-based study of 50-64 year olds to assess the association between lung function (mea

Influence of DOTA chelator position on biodistribution and targeting properties of (111)In-labeled synthetic anti-HER2 affibody molecules

Affibody molecules are a class of affinity proteins. Their small size (7 kDa) in combination with the high (subnanomolar) affinity for a number of cancer-associated molecular targets makes them suitable for molecular imaging. Earlier studies demonstrated that the selection of radionuclide and chelator may substantially influence the tumor-targeting properties of affibody molecules. Moreover, the p

Agrar ojämlikhet i Sverige studerad med bevillningstaxeringen som källa, 1870–1920

This Swedish-language investigation concerns the usefulness of the Swedish property tax, introduced in 1862, as a source for studying wealth inequality in the agrarian sector. A one percent sample of all taxpayers in rural areas, following the original taxation lists archived at the National Archives in Stockholm, has been made for four counties in three years: 1870, 1900, 1920. The counties are M

Nurses’ Work-Related Mental Health in 2017 and 2020 : A Comparative Follow-Up Study before and during the COVID-19 Pandemic

The COVID-19 pandemic put a lot of strain on healthcare organizations. Nurses account for over 50% of healthcare staff, and how nurses perform in their work is influenced by a number of human and work environmental factors. However, to our knowledge, there has not been a previous study with the intention to look at all areas that affect a sustainable working life and how these impact nurses’ menta

Long-term consequences of bilateral cavernous crush injury in normal and diabetic rats : a functional study

A recent statement from the European-Society-for-Sexual-Medicine has highlighted the limitations of using the rat model for nerve-sparing prostatectomy. The use of young rats with no comorbidities and the early evaluation of the erectile function (EF) are deemed a source of bias. Our aim was to evaluate the long-term consequences in EF of bilateral nerve cavernous crush- injury (BNCI) in type 1 di

Oxygen atom transfer catalysis by dioxidomolybdenum(VI) complexes of pyridyl aminophenolate ligands

A series of new cationic dioxidomolybdenum(VI) complexes [MoO2(Ln)]PF6 (2–5) with the tripodal tetradentate pyridyl aminophenolate ligands HL2-HL5 have been synthesized and characterized. Ligands HL2-HL4 carry substituents in the 4-position of the phenolate ring, viz. Cl, Br and NO2, respectively, whereas the ligand HL5, N-(2-hydroxy-3,5-di-tert-butylbenzyl)-N,N-bis(2-pyridylmethyl)amine, is a der

Short-term exposure to ambient particle gamma radioactivity is associated with increased risk for all-cause non-accidental and cardiovascular mortality

BACKGROUND: Recent studies have found that particulate matter (PM) attached radioactivity was associated with certain adverse health effects including increased blood pressure and lung dysfunction. However, there has been no investigation on the direct effect of PM radioactivity on mortality.METHODS: Exposures to ambient PM gamma activities were determined using U.S. EPA RadNet data. Data on daily

Pandrug-resistant Klebsiella pneumoniae isolated from Ukrainian war victims are hypervirulent

OBJECTIVES: Carbapenem- and colistin-resistant Klebsiella pneumoniae were isolated from war victims treated in hospitals in Ukraine. The question was whether these pandrug-resistant K. pneumoniae are pathogenic and capable of causing disease in a broader context.METHODS: Klebsiella pneumoniae clinical isolates (n = 37) were tested for antibiotic resistance and subjected to whole-genome sequencing

Validation of the Health Assessment Tool (HAT) based on four aging cohorts from the Swedish National study on Aging and Care

Background: As global aging accelerates, routinely assessing the functional status and morbidity burden of older patients becomes paramount. The aim of this study is to assess the validity of the comprehensive clinical and functional Health Assessment Tool (HAT) based on four cohorts of older adults (60 + years) from the Swedish National study on Aging and Care (SNAC) spanning urban, suburban, and