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The aim of this study was to examine whether autoantibodies to: ZnT8-Tryptophan (ZnT8WA), ZnT8-Arginine (ZnT8RA) or ZnT8-Glutamine (ZnT8QA) correlated with C-peptide or other autoantibodies and to assess diagnostic sensitivity of ZnT8WRQA. Specimens from 270 newly diagnosed diabetic subjects (age 15--34 years) and after five 5 years duration of disease were examined. Four linear regression models

Knowledge of the natural emissions of mercury in the Mediterranean basin, which has large cinnabar anomalies, has particular weight as these deposits could be an important source of atmospheric mercury. Data on the degassing rate of mercury from soils sampled both in mineralized areas (Mt. Amiata, Italy and Almaden, Spain) and rural areas are reported. Measurements were carried out 'in situ' using

In a world where distributed power generation and deregulation of energy markets are on everyone's agenda, the need for highly efficient power plants with short lead times is greater than ever. Although at present combined cycles provide a solution, development of ever more advanced machines to increase efficiency and lower the environmental impact has led to high maintenance costs and a decrease

Abstract in UndeterminedA correct lighting solution guarantees appropriate working conditions, while saving energy. Today it is well-known that the light influences our visual perception, our emotions and our biological system, thus our health and productivity. Four identical classrooms of a high school in Helsingborg, Sweden, were equipped with two different lighting concepts: classic pendants wi

Deception research has neglected the fact that legal-workers often have to try to detect deceit on the basis of statements derived from pairs of suspects, each having been interrogated repeatedly. To remedy this shortcoming we conducted a study where each member of 10 truth-telling pairs and 10 lying pairs was interrogated twice about an alibi. One hundred and twenty undergraduate students were en

Popular Abstract in Swedish Ser man bakåt i historien har människan alltid försökt reparera eller ersätta vävnader i kroppen vid skador. En av de äldsta rapporterna om användande av biomaterial är runt 4000 år gammalt. I detta fall användes linnefibrer som suturmaterial. Från början användes naturliga material som collagen, silke, hår, bomull och olika cellulosamaterial. Under senare hälften av 19The aim of the this thesis was surface modification of a biomedical polyurethane (PUR), Pellethane 2363-80AE*, to improve the biocompatibility. Surfaces modified by poly(ethylene oxide) (PEO) were prepared either by grafting PEO covalently at the PUR surface by a two-step reaction, or by using amphiphilic polymers containing PEO as the hydrophilic part. The amphiphilic polymers consisted of one co

Popular Abstract in Swedish ?DNA-mikromatriser eller genchips? är idag väletablerade verktyg inom biologisk forskning och klinisk diagnostik. Genmikromatriser kan exempelvis användas för att i mikroskala studera genetiska skillnader mellan sjuka och friska vävnader. Informationen som då erhålls kan ge värdefulla upplysningar om sjukdomens natur och användas vid utveckling av nya läkemedel. GenernAntibody-based microarrays are among the novel class of rapidly evolving proteomic technologies. In recent years, antibody microarrays have emerged as a unique tool for high-throughput protein expression profiling with great promise within biomedicine and a wide range of potential applications, including disease diagnostics and biomarker discovery. In order to evolve the technology from small dedi

In order to compare measurements in different laboratories and with different models and measuring principles a small Round Robin test was suggested. 12 test institutions were able to join the study (with foot model sizes from 254 mm to 275 mm and test boot sizes from 41 to 44). We got also a declaration of interest from 2 other institutes that were not able to carry out the tests now. A database

Background Several trials evaluating the effect of prostate-specific antigen (PSA) testing on prostate-cancer mortality have shown conflicting results. We updated prostate-cancer mortality in the European Randomized Study of Screening for Prostate Cancer with 2 additional years of follow-up. Methods The study involved 182,160 men between the ages of 50 and 74 years at entry, with a predefined core

Clubhouses are supposed to follow the International Clubhouse Standards, but they also need to make adaptations according to national and local contexts. This article compares the implementation of peer support elements in the clubhouse model in two different social contexts: the Swedish and the Japanese welfare systems. Participatory observations and interviews with members and staff at a Swedish

OBJECTIVE: The brain derived neurotrophic factor (BDNF) locus has been implicated in psychiatric and substance related disorders. Recent genome-wide association studies (GWAS) have shown strong associations between single nucleotide polymorphisms in BDNF, smoking behaviour and high body mass index (BMI). Our aim was to test whether genetic BDNF variation alters the risk of smoking related morbidit

Many animals can use the polarization of light in various behavioural contexts. Birds are well known to use information from the skylight polarization pattern for orientation and compass calibration. Still, there are few controlled studies of polarization vision in birds, and the majority of them have not been successful in convincingly demonstrating polarization vision. We used a two-alternative

Aluminum-based sacrificial anodes were installed to reinforced concrete to stop ongoing corrosion in cooling water tunnels in a Swedish nuclear power plant. The steel rebars were also unintentionally connected to stainless steel water pumps. Therefore, the consumption rate of the sacrificial anodes was higher than predicted. An experimental and a field study were performed to assess if the steel r

BACKGROUND: Thrombosis is one of the most important causes of morbidity in the medical field. Several independent in vitro studies have shown that the fibrinolytic process may be enhanced by ultrasound, but the effect of ultrasound on thrombus formation in vivo is unexplored. The present study was designed to investigate this matter. METHODS: In a blind randomized study, standardized arteriotomies

A good indoor thermal climate is important. To reduce energy demands for space heating, individual metering and billing (IMB) for space heating costs is common, though not yet in Sweden. To obtain a better picture of the thermal climate conditions, the distribution of the measured indoor temperatures was investigated in each apartment in 14 apartment blocks with a total of 419 apartments. All bloc

Background: Adjusting medication for uncontrolled asthma involves selecting one of several options from the same or a higher treatment step outlined in asthma guidelines. We examined the relative benefit of introducing budesonide/formoterol (BUD/FORM) maintenance and reliever therapy (Symbicort SMART (R) Turbuhaler (R)) in patients previously prescribed treatments from Global Initiative for Asthma

BACKGROUND: In animals, we have previously done successful lung transplantations using organs from non-heart-beating donors. We have also developed an ex-vivo system of assessing the function of such organs before transplantation. The next stage was to try the technique in human beings. Bearing in mind the sensitive ethical issues involved, our first aim was to find out what procedures would be ac

This study describes the development of a high throughput procedure for the extraction, purification, and quantification of all 16 polycyclic aromatic hydrocarbons (PAHs) on EPA's priority list, subject to biodegradation assays in a creosote-contaminated soil. We used various combinations of solvents, temperatures, ultrasonication, tumbling, saponification, vacuum centrifugation, adsorption chroma

Objective: To characterise uterine proteoglycans and changes therein during pregnancy and labour. Study Design: Uterine samples were collected from 6 non-pregnant, 10 term-pregnant and from 10 women in active tabour. The proteoglycans were extracted by 4 M guanidine hydrochloride and precipitated with Alcian Blue. They were separated by electrophoresis and identified by Western blotting. Results: