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The central complement inhibitor factor I (FI) degrades activated complement factors C4b and C3b in the presence of cofactors such as C4b-binding protein, factor H, complement receptor 1 and membrane cofactor protein. FI is a serine protease composed of two chains; the light chain comprises the serine protease domain, while the heavy chain contains several domains: the FI and membrane attack compl
OBJECTIVES: This study examined which individual and national factors affect condom use among adolescents. STUDY DESIGN: Multilevel analysis. METHODS: This study reviewed the data on bullying, alcohol use and condom use provided by 18 European countries and subnational entities in the Health Behaviour in School-Aged Children survey. Another eight contextual variables were also analysed. Three mult
To study and compare associations between life satisfaction and standard of living, health, and coping behaviour in older single-living women in two countries with different political, economical and cultural situations: Latvia and Sweden. Cross sectional data included 260 Latvian and 288 Swedish women, aged 75-84 and 80-89, from the ENABLE-AGE Survey Study. Life satisfaction was assessed by the q
PURPOSE: The neural tolerance of the recently introduced dimer iodixanol (320 g I/l) was compared with that of the dimer iotrolan (300 g I/l) and of the monomer iopamidol (300 g I/l), both used in clinical myelography.MATERIAL AND METHODS: Non-anaesthetised rabbits were injected into the cisterna magna with Ringer's solution (control) or contrast media (CM) at doses of 1.0 or 0.5 ml/kg b.w. The be
Konkurrensrättsliga skadeståndsprocesser förekommer sällan i Sverige, trots att möjligheten att erhålla skadestånd på konkurrensrättslig grund har funnits länge i svensk rätt. Detsamma gällde under lång tid även i övriga EU-medlemsstater, fastän Europeiska unionens domstol erkände rätten till skadestånd redan år 2001. En central processuell utmaning är att skadelidande ofta saknar tillgång till nöDespite the long-standing availability of damages claims under Swedish competition law, such disputes remain uncommon. The same was true for a long time in other EU Member States, even though the Court of Justice of the European Union recognized the right to damages as early as 2001. A central procedural challenge is that injured parties often lack access to the evidence they need. The Damages Dir
Who’s Worth Identifying examines the reasonings behind the decision to exclude the use of forensic investigative genetic genealogy, or FIGG, to identify unidentified human remains belonging to victims of crime in Sweden. After FIGG was used to solve a double homicide in Linköping in 2020 the Swedish Police Authority published a report on its use. After the publishing of the report the Swedish Auth
Introduction: This study investigates clinical reported challenges and ethical-professional considerations related to the use of the International Trauma Interview (ITI) and International Trauma Exposure Measure (ITEM) with trauma-affected refugees in Denmark. These instruments were implemented in 2023 across several Danish refugee rehabilitation clinics to screen for trauma and assess ICD-11 PTSD
High-resolution rainfall data are essential for various hydrological applications such as flood modeling, soil erosivity studies, and urban water management. However, the scarcity of subdaily data, particularly in remote regions, necessitates reliable disaggregation methods to derive finer temporal resolutions from daily rainfall records. This study introduces a novel hybrid approach combining the
Title Factors for success : a study of school libraries at compulsory schools and how to integrate them in the education Abstract This Master's thesis aims to identify success factors for the integration of school libraries in the education. The search for factors are concentrated to three areas: control documents for the school and school library, the Principal and organisation and the col
Commercial private equity as an investment industry have quickly grown since its formation in the late 80’s, and now account for a significant part of the investments made both globally and in Sweden. In 2014 the Swedish commercial private equity companies had a combined turnover of 311 billion SEK, accounting for around 9 % of Sweden’s GNP. The sector has been studied extensively by the investmen
Background: Adverse skin reactions to continuous glucose monitors (CGMs) and devices for continuous subcutaneous insulin infusions (CSIIs) (“diabetes medical devices” (MDs)) are well known. However, epidemiological studies on prevalence and skin rash details are lacking. The objective of this study was to describe the prevalence and details of skin rash to diabetes MDs in adults with type 1 diabet
Portal frame bridges are one of the most popular types of bridges in Sweden. These bridges consists of a framework structure that mitigates the use of bearing supports and expansion joints which in turn makes them economically viable, efficient and robust. The structure makes use of having vertical surfaces such as abutment walls that are in contact with soils, meaning that braking forces, thermal
In the scientific domain of high energy physics (HEP), the Worldwide LHC Computing Grid (WLCG) was created in order to handle the huge compute and storage needs of the experiments at Large Hadron Collider (LHC). Today WLCG combines about 1.4 million computer cores and 1.5 exabytes of storage from over 170 sites in 42 countries. What ties the sites together is the middleware installed at each site,
Background and objective: The European Association of Urology (EAU) renal cell carcinoma (RCC) guideline panel has updated their evidence-based guidelines and recommendations for the management of RCC. Here we present a summary of the 2025 RCC guidelines updated with standardised methodology to provide reproducible evidence for the management of RCC. Methods: For the 2025 update, a literature sear
Objective Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are globally prevalent chronic diseases that affect millions of individuals in ageing populations. Hip and knee replacements are well established and effective treatments in patients suffering from end-stage OA. Understanding how T2DM influences the outcomes of these surgeries is important for optimising patient care and improving s
Various aspects related to establishing dose constraints (DCs) in interventional cardiology (IC) based on their features as defined in the recommendations of Publication 103 by the ICRP and the Basic Safety Standard Directive are presented. Preliminary DC values are proposed for the personal dose equivalent at 10 mm and 3 mm depth (Hp(10) and Hp(3) respectively). The methodology was based on the a
Objective: To investigate the dynamic changes of soluble fms-like tyrosine kinase−1 (sFlt−1), placental growth factor (PlGF) and their ratio in maternal plasma, from preeclampsia diagnosis to postpartum, evaluating its clinical utility. Methods: Single-center prospective longitudinal cohort study with repeated sample collection in women with established preeclampsia (PE). Seventy-five (n = 75) wom
