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The role of anti-epithelial growth factor receptor monoclonal antibodies (anti-EGFR MoAbs) in treatment-related electrolyte disorders is still controversial. Therefore, we conducted a meta-analysis of published randomized controlled trials (RCTs) to evaluate the incidences and overall risks of all-grade and grade 3/4 electrolyte disorder events. We searched relevant clinical trials from PubMed, EM

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Introduction: Epidemiological studies on elite female ice hockey players are lacking but needed to tailor preventive efforts in this growing group of athletes. Therefore, the aim of this study was to describe the incidence, prevalence, and burden of health problems in elite female ice hockey players. Methods: In this prospective cohort study, we asked all Swedish Women's Hockey League (SWHL) playe

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Current trends aim at improving the surface integrity of aerospace Ni-based superalloys by reducing the temperature rise in the cutting zone in order to minimize tool wear, as well as reducing the thermally induced tensile residual stresses on the machined surface. The manufacturing industry is also driven by developing high performance sustainable machining processes. Cryogenic machining (CM) usi

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BACKGROUND AND AIMS: Increasing evidence suggests that COVID-19 survivors experience long-term cardiovascular complications possibly through development of vascular damage. The study aimed to investigate whether accelerated vascular ageing occurs after COVID-19 infection, and if so, identify its determinants.METHODS: This prospective, multicentric, cohort study, included 34 centres in 16 countries

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Geographic information systems are used to integrate historical water quality data with information layers derived from diverse sources and represents important tools for the water resources management at watershed scale. This study aimed to collect data sources at the watershed level and compare coincident water quality parameters to find spatial and temporal changes related to land use / land co

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This study attempts to receive insights and thus, expand the general understanding of customers‟ perceptions and associations towards store image for grocery store in an emerging Lithuania market. The case study of Rimi Baltic company is taken as an example. Further on, a qualitative strategy is employed in this research. Information is collected by employing photo elicitation method, tw

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Vi människor och vårt samhälle påverkas mycket av klimatet vi lever i och av de naturliga klimat- och miljövariationer som sker på jorden. Det kan vara kortvariga katastrofartade händelser som tsunamis och jordbävningar men också långsammare och långvariga klimatförändringar som påverkar vårt sätt att leva och bruka jorden. Genom geologiska studier av jordens historia vet vi att klimatet har varieNightingale Island is situated at 37°S in the central part of the South Atlantic Ocean, which is a sensitive location for variations within the Atlantic Meridional Overturning Circulation (AMOC) and the Southern Hemisphere Westerlies (SHW) wind belt. A peat sequence from the wetland 2nd Pond has been investigated with emphasis on the composition of the deposits, loss on ignition (LOI), total Carbo

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The main purpose of this research is to investigate the genuine problems face by female teacher of Govt. Girls Primary schools and Federal Community Girl Primary School in F.R Peshawar. The main theme of this study is to investigate female teachers’ work related issues in government primary schools and federal community schools?, also what are the available facilities to female teaching staff at g

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This master thesis studies a two-echelon distribution system for perishable items with two non identical retailers. Each location is managed following a standard continuous (R, Q) ordering policy. The demand occurs solely at the retailers and follows independent Poisson processes. Customers are backordered when the retailer is out of stock. The items are considered as fixed lifetime perishables. W

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This project aims to obtain a deeper understanding of what it is like to be young today, and of how young people experience their lives. Identifying and uncovering the process of meaning constitution concerning young people's thoughts and feelings within each subjective individual, and their visions about the future as well as how they experience relations to other people in their surrounding,

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Background. Goodpasture's disease (GP) is a rare but severe disease characterized by anti-glomerular basement membrane antibodies, rapidly progressive glomerulonephritis and lung haemorrhage. The autoantibodies are restricted to a narrow epitope region on the NC1 domain of the alpha3 chain of type IV collagen. GP is strongly associated with major histocompatibility complex (MHC) allele HLA DRB1-15

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A study on the catalytic behaviour of a copper and a platinum titania based monolithic catalyst in the reduction of nitrogen oxides with hydrocarbons in real diesel conditions was carried out. A Volvo TD 7.31 engine was used as gas source, and diesel fuel was the reductant. In these conditions, both catalysts were active in the reduction reaction. The influence of various operating parameters on t

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Myosin light-chain phosphorylation is the primary mechanism for activating smooth-muscle contraction and occurs principally at Ser-19 of the 20 kDa light chains of myosin (LC(20)). In some circumstances, Thr-18 phosphorylation may also occur. Protein kinase C (PKC) can regulate LC(20) phosphorylation indirectly via signalling pathways leading to inhibition of myosin light-chain phosphatase. The go

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This study describes, in quantitative terms, the effects of endothelin-2 and endothelin-3 on vascular tone (resistance) in large-bore arterial resistance vessels (> 25 microns), small arterioles (< 25 microns) and the veins, as well as on capillary pressure and fluid exchange in cat gastrocnemius muscle in vivo. Infusion of endothelin-2 or endothelin-3 (200-1600 ng kg-1 min-1, i.a.) elicited an in

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In a 5-y retrospective follow-up study in southern Sweden that initially included > 1000 individuals with previously diagnosed erythema migrans, factors that influenced the risk of reinfection with Lyme borreliosis were elucidated. The total frequency of reinfection was 4% and the number of tick bites influenced the risk of reinfection: those bitten > 10 times during the observation period had a 4

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Drainage of peatlands increases the transport of suspended solids (SS) and the leaching of nutrients to downstream receiving waters. Increased settling of peat and eutrophication of lakes has been noted in many studies downstream from peat mines. Treatment alternatives have therefore been developed since the early 1980s to reduce the environmental impacts of peat mining. New, efficient methods suc

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Hydrophobic interaction chromatography (HIC) and other capture media are typically produced by grafting different ligands to base matrices at defined surface densities. This often complicates media production. An alternative approach to media involving in situ radical initiated polymerization was used to graft polymer coatings directly at Sepharose(D polymeric base matrices. This method appears su

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During the process of migration, many immigrants undergo a number of changes in their relationships to their religious organisations. One factor that has emerged as especially important in immigrants’ congregational affiliation is the availability of language groups in immigrants’ mother tongues. This article examines how these groups are formed and the roles they play in the lives of their member

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The objective was to explore the meaning of the phenomenon of problem solving in midwifery when the midwife is faced with a critical situation in the absence of an obstetrician or any physician. A qualitative method was used and critical incidents from delivery wards and/or antenatal clinics in the south of Sweden were narrated by midwives and transcribed verbatim. The interwievs were then analyse

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Background. The incidence of non-Hodgkin lymphoma and prevalence of obesity are increasing globally. A suggested positive association between obesity and risk of non-Hodgkin lymphoma has prompted us to investigate the relationship between body mass index (BMI) and risk of malignant lymphoma subtypes in a population-based case-control study. Methods: Telephone interviews were conducted with 3055 ca