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A prospective randomized double-blind trial was performed comparing conventional low-dose heparin with a low molecular weight heparin fragment for thromboprophylaxis in elective general abdominal surgical patients. The first dose of the heparin fragment was given the evening before surgery, and further doses were given thereafter every evening. There were 1002 analysable patients, 826 having recei
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Palatable food is rich in fat and/or sucrose. In this study we examined the long-term effects of such diets on food intake, body weight, adiposity and circulating levels of the satiety peptide leptin and the hunger peptide ghrelin. The experiments involved rats and mice and lasted 5 weeks. In rats, we examined the effect of diets rich in fat and/or sucrose and in mice the effect of a high fat diet
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Optical spectroscopy provides powerful means for studying geophysical gas emissions. An extensive research program in this field has been performed by Swedish researchers in collaboration with European partners during the last 10 years, and a review of the activities and results is given. The techniques suitable for geophysical gas monitoring include the differential absorption lidar (DIAL), diffe
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BACKGROUND: In animals, we have previously done successful lung transplantations using organs from non-heart-beating donors. We have also developed an ex-vivo system of assessing the function of such organs before transplantation. The next stage was to try the technique in human beings. Bearing in mind the sensitive ethical issues involved, our first aim was to find out what procedures would be ac
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The influence of solar radiation on the ability of dissolved organic matter (DOM) to support bacterial growth, was studied in the eastern Atlantic sector of the Southern Ocean during the SWEDARP 1997/1998 cruise with SA Agulhas December 1997-February 1998. Vertical profiles of water samples (2-3000m) were obtained from the Spring Ice Edge (SIE, 60degreesS, high chlorophyll-a) and from the Winter I
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Aims To describe atrial fibrillation (AF) management in member countries of the European Society of Cardiology (ESC) and to verify cardiology practices against guidelines. Methods and results Among 182 hospitals in 35 countries, 5333 ambulant and hospitalized AF patients were enrolled, in 2003 and 2004. AF was primary or secondary diagnosis, and was confirmed on ECG in the preceding 12 months. Cli
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The conditions for successful epitaxial lateral overgrowth of W patterns by InAs using low-pressure metalorganic vapour phase epitaxy were studied. The substrates used were InAs (0 0 1) wafers and the range of growth temperatures between 500 and 600 degrees C. The selective growth was investigated as a function of the V/III-ratio on W-ring test structures and wires oriented in different directions
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High-spin states of the neutron deficient (100)pd nucleus have been investigated via the Cr-50(Ni-58, 4p alpha) and Zn-70(S-36,6n) heavy-ion induced reactions. For the detection of evaporated particles and gamma rays the NORDBALL array equipped with ancillary detectors and the EUROGAM II detector system were utilized. By the use of in-beam spectroscopic methods 89 transitions belonging to (100)pd
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A mathematical model was developed for the drying of paper in a multi-cylinder drying section. The model is based on the unsteady state, one-dimensional heat conduction equation, which is applied to both the cylinder shell and the paper web. No internal mass transfer phenomena were modeled explicitly. Great emphasis ws placed on finding the proper heat and mass transfer coefficients that are integ
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BACKGROUND: Thrombosis is one of the most important causes of morbidity in the medical field. Several independent in vitro studies have shown that the fibrinolytic process may be enhanced by ultrasound, but the effect of ultrasound on thrombus formation in vivo is unexplored. The present study was designed to investigate this matter. METHODS: In a blind randomized study, standardized arteriotomies
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Results of reliability studies on physical performance tests are often conflicting. The main purpose of this study was to analyse the inter-rater reliability and between-days repeatability of physical performance tests on a female working population. Twenty-two nursing aides/ assistant nurses were tested twice, with, on average, a 5-day interval. Seventeen of these were tested again, after an aver
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Neuromuscular electrical stimulation (NMES) technique is a dual-channel electrotherapy system designed specifically for the treatment of pharyngeal dysfunction. The purpose of this study was to evaluate and compare the outcome of NMES versus traditional swallowing therapy (TT) in stroke patients. Three European swallowing centers participated in this randomized trial. Twenty-five patients (16 men
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The aim of this study was to evaluate thermo-thresholds in autologous reconstructed microtic ears. Nineteen patients with unilateral microtia were investigated no less than two years after the last operation (3.6+/-1.7 years). Their normal corresponding ear acted as controls. Eight healthy children were also investigated to illustrate technical differences between measuring the two sides. Thermal
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The aim of this study was to examine whether autoantibodies to: ZnT8-Tryptophan (ZnT8WA), ZnT8-Arginine (ZnT8RA) or ZnT8-Glutamine (ZnT8QA) correlated with C-peptide or other autoantibodies and to assess diagnostic sensitivity of ZnT8WRQA. Specimens from 270 newly diagnosed diabetic subjects (age 15--34 years) and after five 5 years duration of disease were examined. Four linear regression models
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Hip fractures are a major cause of hospital stay among the elderly, and result in increased disability and mortality. In this study from 1 April 2003 to 31 March 2004, the influence of optimised treatment of hip fracture on time to operation, length of hospital stay, reoperations and mortality within 1 year were investigated. Comparisons were made between the first 210 patients in the period and t
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Gaboxadol (THIP; 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) is an agonist at GABA(A) receptors. THIP concentrations (0.01-50 mM) were applied rapidly to Sf9 cells expressing the human alpha(1)beta(2)gamma(2S) GABA(A) receptors. The EC50 values for the peak current in THIP alone or THIP plus 1 muM diazepam were 154 and 53 muM, respectively. In supersaturating THIP (10-50 mM) the rate of curren
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The chromosome number of the polyploid species Glechoma hederacea was found to be 2n = 36 in a sample of 93 ramets derived from 27 sites in N and C Europe. Variation in 10 enzymes was surveyed in material from S Sweden and S Czech Republic. The genetic control of variation was investigated using segregating progeny from crosses and self-fertilized heterozygous plants. The generic analysis comprise
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beta-Glucosidase genes of fungal origins were isolated and heterologously expressed in Saccharomyces cerevisiae to enable growth on the disaccharide, cellobiose. To promote secretion of the beta-glucosidases, the genes were fused to the secretion signal of the Trichoderma reesei xyn2 gene and constitutively expressed from a multi-copy yeast expression vector under transcriptional control of the S.
