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Quantitative analysis of phantom studies of 111In and 68Ga imaging of neuroendocrine tumours

Background: Nuclear medicine imaging of neuroendocrine tumours is performed either by SPECT/CT imaging, using 111In-octreotide or by PET/CT imaging using 68Ga-radiolabelled somatostatin analogs. These imaging techniques will give different image quality and different detection thresholds for tumours, depending on size and activity uptake. The aim was to evaluate the image quality for 111In-SPECT a

Two theoretical strands of social capital, and total, cardiovascular, cancer and other mortality : A population-based prospective cohort study

The aim is to prospectively investigate both the “cohesion” and “network” perspectives of social capital in relation to total, cardiovascular (CVD), cancer and all other causes mortality. The 2008 public health survey in Scania was a postal questionnaire with three letters of reminder, and it was answered in the Autumn by 28,198 respondents (55% participation) aged 18–80 from a stratified random s

Geographic origin and migration phenology of European red admirals (Vanessa atalanta) as revealed by stable isotopes

Background: Long-distance migration has evolved multiple times in different animal taxa. For insect migrants, the complete annual migration cycle covering several thousand kilometres, may be performed by several generations, each migrating part of the distance and reproducing. Different life-cycle stages and preferred orientation may thus, be found along the migration route. For migrating red admi

Search for high mass dilepton resonances in pp collisions at root s=7 TeV with the ATLAS experiment

This Letter presents a search for high mass e(+)e(-) or mu(+)mu(-) resonances in pp collisions at root s = 7 TeV at the LHC. The data were recorded by the ATLAS experiment during 2010 and correspond to a total integrated luminosity of similar to 40 pb(-1). No statistically significant excess above the Standard Model expectation is observed in the search region of dilepton invariant mass above 110

Effects of the Gonadotropin-Releasing Hormone Antagonist Ganirelix on Normal Micturition and Prostaglandin E-2-Induced Detrusor Overactivity in Conscious Female Rats

BACKGROUND: Gonadotropin-releasing hormone (GnRH) antagonists have been reported to have beneficial effects on lower urinary tract symptoms in patients with benign prostatic hyperplasia. OBJECTIVE: Our aim was to investigate the effects of ganirelix, a GnRH receptor antagonist, on bladder function and detrusor overactivity (DO) in female rats. DESIGN, SETTING, AND PARTICIPANTS: Female Sprague-Dawl

Age and gender differences in risk factor burden, myocardial dysfunction and cardiovascular events in relation to glucose metabolism

Popular Abstract in Swedish Studier har visat att inte bara individer med diabetes utan ocksa de som har forstadier till diabetes, namligen forhojt fasteblodsocker och nedsatt glukostolerans, loper en okad risk for att drabbas av saval hjartkarlsjukdom som hjartsvikt. Daremot har man sett att den okade risken forenad med diabetes verkar minska med aldern. Studier pa aldre individer ar dock sparsamThe risk of cardiovascular disease (CVD) and heart failure (HF) among individuals with diabetes is at least two times greater than in non-diabetic subjects. However, the excess risk of CVD in diabetic subjects seems to decrease with age. As the majority of patients with diabetes, CVD and HF are elderly it is important to establish the extent to which the associations between these conditions diffe

Laminar burning velocities of primary reference fuels and simple alcohols

Laminar burning velocities for methanol, ethanol, and binary and quaternary mixtures of these with isooctane and n-heptane, have been determined using the heat flux method on a flat flame adiabatic burner. Measurements were done for an equivalence ratio range between 0.7 and 1.5 and for a range of temperatures between 298 K and 358 K at atmospheric pressure. The present study expands the available

Micro-mechanisms of a laminated packaging material during fracture

The micro-mechanisms of fracture in a laminate composed of an aluminium foil and a polymer film are considered in this study. The laminates as well as the individual layers, with and without premade centre-cracks, were tensile tested. Visual inspection of the broken cross-sections shows that failure occurs through localised plasticity. This leads to a decreasing and eventually vanishing cross-sect

Electrochemical behavior and application of Prussian blue nanoparticle modified graphite electrode

Prussian blue nanoparticles (PBNPs) were immobilized on the surface of a graphite electrode (GE) through a simple adsorption route and then the modified surface was covered with a layer of Nafion. The electrochemical behavior of the resulting sensor was investigated using cyclic voltammetry and chronoamperometry. The sensor showed good electrocatalytic activity toward hydrogen peroxide reduction,

Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers

Fibril formation of islet amyloid polypeptide (IAPP) is associated with cell death of the insulin-producing pancreatic beta-cells in patients with Type 2 Diabetes Mellitus. A likely cause for the cytotoxicity of human TAPP is that it destroys the barrier properties of the cell membrane. Here, we show by fluorescence confocal microscopy on lipid vesicles that the process of hIAPP amyloid formation

Search for new phenomena in the WW -> vertical bar v vertical bar ' v ' final state in pp collisions at root s=7 TeV with the ATLAS detector

This Letter reports a search for a heavy particle that decays to WW using events produced in pp collisions at root s = 7 TeV. The data were recorded in 2011 by the ATLAS detector and correspond to an integrated luminosity of 4.7 fb(-1). WW -> lvl'v' (l,l' = e or mu) final states are considered and the distribution of the transverse mass of the W W candidates is found to be consistent with Standard

The G protein-coupled estrogen receptor 1 (GPER/GPR30) does not predict survival in patients with ovarian cancer

Background: Even though ovarian tumors are not generally considered estrogen-sensitive, estrogens may still have an impact on ovarian tumor progression. The recently identified trans-membrane estrogen receptor GPER is involved in rapid estrogen signaling. Furthermore, it binds selective estrogen receptor modulators with agonistic effect, which could explain tamoxifen controversies. Methods: GPER m

Interaction between phosphofructokinase and aldolase from Saccharomyces cevisiae studied by aqueous two-phase partitioning

Phosphofructokinase (EC 2.7.1.11) and aldolase (EC 4.1.2.13) have been highly purified from Saccharomyces cerevisiae by improved protocols. Partitioning of the enzymes in aqueous polymer two-phase systems was used to detect complex formation. The partition of each enzyme was found to be affected by the presence of the other enzyme. AMP affected the partition of the individual enzymes as well as th

ABO exon and intron analysis in individuals with the A(weak)B phenotype reveals a novel O-1v-A(2) hybrid allele that causes four missense mutations in the A transferase

Background: Since the cloning in 1990 of cDNA corresponding to mRNA transcribed at the blood-group ABO locus, polymorphisms due to ethnic and/or phenotypic variations have been reported. Some subgroups have been explained at the molecular level, but unresolved samples are frequently encountered in the reference laboratory. Results: ABO blood grouping discrepancies were investigated serologically a

Kinetic investigation of a PC(sp(3))P pincer palladium (II) complex in the Heck reaction

An investigation of the kinetics of the Heck reaction between 4-iodoanisole and styrene catalysed by {cis-1,3-bis[(di-tert-butylphosphino)methyl]-cyclohexane} palladium (11) iodide (1) has been performed in DMF-d(7) solution. Based on mercury poisoning experiments a heterogeneous palladium catalyst formed from the PCsp3P Pd(II) pre-catalyst is proposed. Saturation behaviour with respect to the ole

Pulsed electric field treatment for solid-liquid extraction of red beetroot pigment: mathematical modelling of mass transfer

The extraction of red pigment and conductive matters from individual red beet tissue slices following pulsed electric field pretreatment of different durations was compared with a two dimensional bimodal Fickian diffusion model. The process appeared to be governed by two apparent diffusion coefficients, one slow and one fast. The values of these coefficients were independent of the duration of tre

Synthesis and conformational studies of a Leu-enkephalin amide analogue containing a ferrocene substructure

Solution phase synthesis of a constrained Leu(5)-enkephalin amide analogue 10 is reported, in which the cyclic ferrocenyl containing subunit 7 was introduced as a mimetic of the tetrapeptide Tyr-Gly-Gly-Phe unit. Temperature dependence of the chemical shift of the amide protons of 10 indicated a hydrogen bond between the same amino acid residues as observed for the natural Leu-enkepalin in the sin

Anaerobic batch co-digestion of sisal pulp and fish wastes

Co-digestion of various wastes has been shown to improve the digestibility of the materials and biogas yield. Batchwise digestion of sisal pulp and fish waste was studied both with the wastes separately and with mixtures in various proportions. While the highest methane yields from sisal pulp and fish waste alone were 0.32 and 0.39 m(3) CH4/kg volatile solids (VS), respectively, at total solid (TS

Degradation of toxaphene in water during anaerobic and aerobic conditions

The degradation of technical toxaphene in water with two kinds of bioreactors operating in sequence was studied. One packed bed reactor was filled with Poraver(R) (foam glass particles) running at anaerobic conditions and one suspended carrier biofilm reactor working aerobically. Chemical oxygen demand (COD), chloride, sulphate, pH, dissolved oxygen, total toxaphene and specific toxaphene isomers