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Inorganic phosphate is an essential molecule for all known life. Organisms have developed many mechanisms to ensure an adequate supply, even in low-phosphate conditions. In prokaryotes phosphate transport is instigated by the phosphate-binding protein (PBP), the initial receptor for the ATP-binding cassette (ABC) phosphate transporter. In the crystal structure of the PBP-phosphate complex, the pho

Objective To assess the accuracy of the Wells rule for excluding deep vein thrombosis and whether this accuracy applies to different subgroups of patients. Design Meta-analysis of individual patient data. Data sources Authors of 13 studies (n=10 002) provided their datasets, and these individual patient data were merged into one dataset. Eligibility criteria Studies were eligible if they enrolled

Cathodoluminescence at 8 K is used to compare the optical properties of AlGaAs-capped GaAs nanowires, grown by metal-organic vapour phase epitaxy and seeded by gold particles prepared by different methods. Six different methods were used to fabricate and deposit gold seed particles onto GaAs substrates: colloid particles, aerosol particles and particles defined by electron beam lithography. The na

Popular Abstract in Swedish Pankreascancer (cancer i bukspottkörteln) drabbar ungefär 900 personer om året i Sverige. Tumörformen har tidigare varit vanligare hos män men är numera lika vanlig hos män och kvinnor. Pankreascancer är ovanligt före 40 års ålder, men ökar stadigt med åldern och ungefär 80% av dem som drabbas är över 60 år gamla. Pankreascancer är en aggressiv tumörform och på grund av

Popular Abstract in Swedish Medfödda hjärtfel hos barn är förenade med en varierande kombination av förtjockning av hjärtmuskeln, volym- och tryckbelastning av hjärtat, samt nedsatt syremättnad i blodet. Hos barn med medfödda hjärtfel, och förvärvade hjärtsjukdomar ändringar i kranskärlsblodflödet uppstå och påverka hjärtfunktionen eller leda till hjärtinfarkt. En tillförlitlig non-invasiv metod bHeart diseases in children cause different combinations of myocardial hypertrophy, increased intra-ventricular pressures, volume overload and decreased oxygen saturation. This may affect basal coronary flow and the ability of the heart to maximally increase coronary flow. Transthoracic and intracoronary Doppler techniques were used to register coronary flow and coronary flow reserve (CFR) in norma

High levels of biodegradable dissolved organic carbon can affect odor, taste, color and chemical oxygen demand of distributed drinking water as a consequence of bacterial growth (Frias et al, 1995; Escobar, I.C. and Randall, A.A., 2001). The water industry would be able to improve the quality of distributed drinking water if spatial and temporal variations of BDOC could be mapped in the distributi

The aim of this thesis is to present experiences and lessons learned from the initial implementation process of the rating system STARS at Washington University in St. Louis: mainly the strengths/opportunities can be used to overcome the weaknesses/threats that the STARS implementation may entail. Strengths and opportunities such as increased student involvement in processes such as assessing sust

In this master thesis a process in Delmia was created for digital test assembly. Delmia is a computer program for simulations, at Scania Delmia is used for simulating truck assembly. The process created was made to be easily reused in future tests. The base of the process came from the best practice document for manufacturing at Scania. To do this a study of the systems at Scania was made to get a

There is a limited amount of research regarding the use of information systems (IS) augmenting organizations ecological sustainable initiatives. While the field of Green IT somewhat has been studied, Green IS has not received the same attention in scientific research. In this report we have aimed to identify areas that are poorly, or have yet to be, augmented by IS. Thus highlighting areas where o

Authors: Anna Flodberg & Ellinor Fridlund Title: Sheltered accommodation for children who experience domestic violence – A study on a how child’s perspective is applied. [translated title] Supervisor: Bodil Rasmusson Assessor: Anna Angelin The purpose of this study was to investigate, describe and analyze what it means for children to get to and staying in shelters, from professionals' p

This essay aims to discuss the complicacy concerning minority and indigenous rights and its complex relation to other international law instruments. In this research I focus on the situation that occurred when the Bolivian president sent an amendment to the Secretary General concerning the withdrawal of the two articles regarding coca leaf-chewing in the Single Convention on Drugs. The member-stat

Delirium is a brain dysfunction often occurring in the intensive care unit (ICU); and frequently missed. This study aimed to investigate the compliance of ICU-nurses to a CAM-ICU implementation.Methods: Implementation guidelines in present study stated that a patient presumed to stay on the ICU for more than 24 hours, and who was 18 years or older was to be monitored for delirium using the Confusi

Evidence supports an important role for beta-amyloid (A beta) in the pathogenesis of Alzheimer's disease ( AD). Here, we investigate baseline levels of the 40- and 42-amino-acid-long A beta peptides (A beta 40 and A beta 42) in cerebrospinal fluid (CSF) from a cohort of patients with mild cognitive impairment (MCI, n = 137) in relation to the final diagnosis after 4 - 6 years of follow-up time. CS

Background: Craniopharyngioma is a parasellar tumour that, although benign, tends to behave aggressively. It can occur at any age but most commonly presents in childhood or adolescence. Objectives: to investigate the frequency and severity of problems associated with craniopharyngioma, using the large international database (KIMS) for adult patients with GH deficiency (GHD), and to assess the diff

The hydrochloride salts of 5-aminolevulinic acid (ALA) and its methyl ester (m-ALA), respectively, were dissolved in a lipid sponge phase comprising monoolein, propylene glycol and aqueous buffer at concentrations of approximately 0.25% and 16% w/w m-ALA. The iontophoretic and passive delivery of ALA and m-ALA from this formulation through porcine skin in vitro were measured and compared to formul

This study reports the defect and electrical transport properties of Nb-doped SrTiO3, Samples with various A/B-ratios were synthesized by a modified glycine-nitrate combustion process and evaluated as a constituent in a SOFC anode. The phase purity and defect structure of the materials have been analyzed with SEM, XRD, TGA, and XANES. The electrical conductivity of Nb-doped strontium titanate (Sr0

A brief period of rapidly recurring hippocampal seizures can lead to the progressive development of a permanent increase of seizure susceptibility over several weeks, so-called 'delayed kindling'. We have analyzed seizure parameters critical for the induction of delayed kindling in two strains of rats characterized by fast and slow rates of traditional kindling, respectively. Forty seizures were p

In this study, we developed a microdispenser technique in order to create protein patterns for guidance of neurites from cultured adult mouse dorsal root ganglia (DRG). The microdispenser is a micromachined silicon device that ejects 100 picolitre droplets and has the ability to position the droplets with a precision of 6-8 mu m. Laminin and bovine serum albumin (BSA) was used to create adhesive a

Objective: To evaluate the safety and performance of Alione Hydrocapillary dressing (Coloplast A/S) in the management of highly exuding chronic venous leg ulcers and compare it with two hydropolymer dressings, Tielle and Tielle Plus (Johnson & Johnson). Method: A comparative clinical trial was conducted on 97 patients with an ankle brachial pressure index ?0.8 and a highly exuding leg ulcer. U

The adsorption of methylene blue (MB) onto zirconium phosphate (ZrP) was studied and the adsorption capacity value and isotherms were determined. The adsorption capacity of ZrP was increased after being exposed to gas phase n-butyl amine. The adsorbed MB on ZrP was used as a modifier material in carbon paste electrode (MCPE), which in turn was used in voltammetric investigations and flow injection