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Episodic memory allows the flexible retrieval of commonalities and idiosyncrasies of overlapping life events. For example, seeing a woman in the city with your colleague's daughter may form an integrated memory representation involving the woman and your colleague. However, you may also keep a specific representation of the city event to talk with your colleague about the circumstances of having m

Cracks in concrete compromise structural integrity by exposing steel reinforcement to corrosion agents, shortening its service life. Fungal-induced calcium carbonate (CaCO3) precipitation via urea hydrolysis offers a fast and robust self-healing mechanism to seal the cracks, extending the lifespan while reducing the carbon (C) footprint of concrete infrastructure. However, current studies rely on

Objectives: In SLE, anti-dsDNA can co-occur with autoantibodies against other chromatin components, like histones and nucleosomes. These antibodies induce type-1 interferon production, a hallmark of SLE. We measured ANA sub-specificities and investigated their associations to inflammatory biomarkers including interferon-regulated chemokines. Methods: We included 93 Sudanese and 480 Swedish SLE pat

BACKGROUND: Irritable bowel syndrome (IBS) is the major form of functional bowel disorders, where the diagnosis is based on set criteria and characterized by abdominal pain and changes in bowel habits. Epidemiological data, alongside self-reported outcomes, are of interest with regard to IBS, as these factors may need to be addressed to optimize underlying IBS. This study aims to examine the effec

Although financial stressors are implicated as risk factors for suicidal behavior, these associations might be confounded by other factors. Furthermore, a move toward high-risk subgroup definition is necessary. The authors used Swedish national registry data to examine the associations between receipt of social welfare, unemployment benefits, or early retirement (N = 627,745-2,260,753) with suicid

Purpose/Background: Ultra-high dose rate radiotherapy (RT) has shown potential for differential normal tissue (NT) sparing (a phenomenon termed the “FLASH effect”), particularly for larger fraction doses (>5 Gy). However, transitioning to hypofractionation may increase late-reacting NT toxicity, counteracting the FLASH effect. This study evaluates whether FLASH-RT can provide netsparing for organs

Background: Data in Ethiopia on the epidemiology of Respiratory Syncytial Virus (RSV) and subtypes among influenza-like illness (ILI) and severe acute respiratory infections (SARI) cases is limited. Here, we assessed the epidemiology of RSV and its subtypes among the pediatric and adult ILI /SARI cases in Ethiopia. Methods: We conducted prospective, multicenter facility-based study from May 2023 t

Background Increased postoperative cardiac troponin (cTn) independently predicts short-term mortality. Previous studies suggest that preoperative cTn also predicts major adverse cardiovascular events (MACE) and mortality after noncardiac surgery. The value of preoperative and perioperative changes in cTn as a prognostic tool for adverse outcomes has been sparsely investigated. Methods and findings

The use of gender-inclusive pronouns aims to make language more inclusive and to reduce biases and prejudices based on gender. Previous research shows that men tend to resist gender-inclusive pronouns more strongly than other individuals. The aim of the current study is to contribute to the understanding of this stronger resistance among men. We hypothesize that men are more negative toward gender

Most studies on the fertility transition have focused either on macro-level trends or on micro-level patterns with limited geographic scope. Much less attention has been given to the interplay between individual characteristics and contextual conditions, including geographic location. Here we investigate the relevance of geography and socioeconomic status for understanding fertility variation in t

This presentation highlights results from a research study of ‘Music Week’; a one-week Swedish music project. The aim of the ‘Music Week’ project was to enable young people with physical impairments to take part in musical activities. Digitally-based musical settings were used in order to provide tools for performing and creating music. The main purpose of the present research study was to explore

Purpose: Some 10% of familial adenomatous polyposis (FAP) and 80% of attenuated polyposis (AFAP) cases remain molecularly unexplained. We scrutinized such cases by exome-wide and targeted methods to search for novel susceptibility genes. Methods: Exome sequencing was conducted on 40 unexplained (mainly sporadic) cases with FAP or AFAP from Finland. The DNA mismatch repair (MMR) gene MLH3 (MutL Hom

Background: Environmental lead exposure has been associated with decreased kidney function, but evidence from large prospective cohort studies examining low exposure levels is scarce. We assessed the association of low levels of lead exposure with kidney function and kidney disease. Study Design: Prospective population-based cohort. Setting & Participants: 4,341 individuals aged 46 to 67 years

We present high-resolution near-edge X-ray absorption fine structure (NEXAFS) measurements at the P L2/3 edges, F K edge, C K edge, and Se M2/3 edges of the quasi-one-dimensional (1D) conductor and superconductor (TMTSF)2PF6. NEXAFS allows probing the donor and acceptor moieties separately; spectra were recorded between room temperature (RT) and 30 K at normal incidence. Spectra taken around RT we

Mixing in wall-jets was investigated in an optical heavy-duty diesel engine with several injector configurations and injection pressures. Laser-induced fluorescence (LIF) was employed in non-reacting conditions in order to quantitatively measure local equivalence ratios in colliding wall-jets. A novel laser diagnostic technique, Structured Laser Illumination Planar Imaging (SLIPI), was successfull

Hypothesis: Some low molecular weight additives can strongly influence the phase behavior of aqueous surfactant systems, and this offers an important handle to control the properties of surfactant solutions and thus to optimize the stability and performance of various formulations. Experiments: The surfactant dioctadecyldimethylammonium chloride (DODAC) self-assembles into two lamellar phases in w

Groundwater quality and quantity are two major challenges in arid and semi-arid regions, due to their critical roles in sustainable agricultural development. Irrigated lands are spread all over Urmia Lake's surrounding plains in Iran. Due to the risk of saltwater intrusion as a result of over-exploitation from groundwater resources, it is important to monitor the groundwater quality and quantity t

Objective: The focus of this study was to determine if there is any significant difference in academic achievement for girls and boys with a cleft compared to the general population of Swedish students at graduation from compulsory school. Design: A retrospective population-based study using data obtained from the Swedish Medical Birth Register that was linked to the Swedish School–Grade Register.

Osteoarthritis is a harmful joint disease but prediction of disease progression is problematic. Currently, there is only one modeling framework which can be applied to predict the progression of knee osteoarthritis but it only considers degenerative changes in the collagen fibril network. Here, we have developed the framework further by considering all of the major tissue changes (proteoglycan con

The polyether ionophore salinomycin has recently captured much interest due to its potent activity against multi-drug resistant cancer cells and cancer stem cells. Previous studies have shown that either acylation of the C20 position or esterification/amidation of the C1 carboxylate moiety is beneficial in terms of biological properties. In this paper, we present the first analogs combining such m