Sökresultat

In Skaraborg, Sweden, the economic responsibility for tax-financed prescription drug costs was transferred from the regional administrative level to the local level (health care centre; HCC) in 2003. The aim of this study was to investigate the impact of this decentralization of economic responsibility on adherence to guidelines for prescribing lipid-lowering drugs. Data from all 24 public HCCs in

The productivity and diversity of plant communities are affected by soil organisms such as arbuscular mycorrhizal fungi (AMF), root herbivores and decomposers. However, it is unknown how interactions between such functionally dissimilar soil organisms affect plant communities and whether the combined effects are additive or interactive. In a greenhouse experiment we investigated the individual and

The sulfation of KCl during biomass combustion has implications for operation and emissions: it reduces the rates of deposition and corrosion, it increases the formation of aerosols, and it leads to higher concentrations of HCl and lower concentrations of SO2 in the gas phase. Rigorously homogeneous systems are required to characterize the gas-phase formation of alkali sulfates. We have measured t

This thesis addresses; (1) the microdialysis experiment, application and methodology to maximise its performance when sampling from enzymatic bioprocesses, (2) electrochemical detection and electrochemical oxidation of carbohydrates on Au as well as Cu electrodes in alkaline solutions, and (3) coupling and maximising the performance of a microdialysis sampling based high performance anion exchange

Popular Abstract in Swedish Slemhinnorna i näsan, bihålorna, nasofarynx (nässvalgrummet), örontrumpeten och främre delen av mellanörat, är beklädda med celler på vars yta det finns flimmerhår (cilier). De ciliebeklädda slemhinnorna är täckta av ett tunt slemskikt som transporteras av ciliernas rörelser. I slemskiktet fastnar inandade partiklar, bakterier och döda celler, och transporteras av cilieThe aim with this thesis was to investigate effects of vasoactive mediators on mucociliary activity and blood flow in rabbit and human experimental models. Mucociliary activity in vivo and ciliary beat frequency (CBF) in vitro were measured with photoelectric techniques. Blood flow was measured with laser Doppler flowmetry. Substance P (SP) and methacholine increased human nasal blood flow. Pretre

High resolution transmission electron microscopy and digital image processing has been used to investigate the structure and properties of inorganic materials. The image processing was performed with the programming language Semper. All routines are listed in the appendix. The local order in the disordered mineral blatterite was investigated, and was found to extend over several unit cells. The

Main objectives of this thesis were to evaluate a gamma scintigraphic method used to quantify drug aerosol deposition in the lung, to investigate the influence of two aerosol inhalation parameters on the distribution of inhaled dry powder within the airways, to assess pulmonary absorption kinetics and bioavailability of an inhaled hydrophilic solute in relation to site of deposition, and to assess

There are many different factors that influence our perception of products i.e. personal, product related and external factors. For designers to be able to address them all when creating new products, we need to deepen our understanding of the totality of perceptual experiences from non-instrumental interaction with products. One way of achieving this is by stimulating the creative process by util

We investigated the potential use of Al2O3:C for medical proton dosimetry. Detector crystals coupled to fiber-optic cables were irradiated in proton beams with energies from 10 to 60 MeV. The key finding is that the initial intensity of the optically stimulated luminescence (OSL) signal is energy independent for small detectors (<0.5mm) and relatively small doses (<0.3Gy). This feature is related

The empirical part of this study is based on a survey of 600 Swedish households and a number of interviews where questions about residential energy behaviour and possible policy instruments for change were raised. The study provides insight into current behavioural patterns and gives a bottom-up perspective on the realistic perspective potentials for change and ways to achieve them. Residential en

Today, the optimization of chromatographic separation is usually based on experimental work and rule of thumb. The process and analytical technology (PAT) initiative, of the US Food and Drug Administration, has provided the opportunity of using model-based approach when designing downstream processing of pharmaceutical substances. A nonlinear chromatography model was used in this study to optimize

An experiment was designed to resolve two largely unaddressed questions about the turnover of N in soils. One is the influence of microbial growth rate on mobilization and remineralization of cellular N. The other is to what extent heterotrophic immobilization of NO3- is controlled by the soil concentration of NH4+. Bacteria were extracted from a deciduous forest soil and inoculated into an aqueou

A molecularly imprinted polymer (MIP) was synthesized with 17 beta-estradiol (E2) as template. It was then capable to recover this compound by 100 +/- 0.6% from a 2 mu g/L aqueous solution. By comparison, E2 recoveries of 77 +/- 5.2%, 87.1 +/- 2.3% and 19.1 +/- 7.8%, were achieved using a non-imprinted polymer (NIP) synthesized under the same conditions (but without template), a commercial C18 ext

The objective of the study was to determine the influence of potato variety, weight and storage time after lifting on the glycaemic index (GI) and resistant starch (RS) content predicted from measurement of the rate and extent of in vitro starch hydrolysis, respectively. The potatoes were either boiled, or boiled and subjected to different heat-cycling conditions selected to promote retrogradation

Previous cultivation may have long-lasting effects on oak forests, e.g., nitrogen (N) and carbon (C) depletion, phosphorus (P) enrichment and lowered soil acidity, which may influence soil processes, wood production and plant diversity. We used a large database on land use to sample 18 sites where oak had been planted 40-80 years ago on continuously forested land and formerly cultivated fields tha

In this work it is shown that domains of ordered dipoles are formed in large droplets made from dipolar particles provided that the dipole-dipole interaction between nearest neighbors is larger than the thermal energy. The size of the domains grows almost linearly with the size of the droplets for droplets containing 1000-30 000 particles. The largest domains occupy around 25-35% of the droplet vo

Objectives. Polyarteritis nodosa (PAN) is a term that has been used to describe a wide variety of vasculitic conditions. In 1994, the Chapel Hill Consensus Conference on the nomenclature of systemic vasculitides proposed that the name classical PAN should be restricted to diseases where there is arteritis in small and medium-sized arteries without the involvement of smaller vessels. Our aim was to

Superporous agarose beads have wide, connecting flow pores allowing large molecules such as plasmids to be transported into the interior of the beads by convective flow. The pore walls provide additional surface for plasmid binding thus increasing the binding capacity of the adsorbent. Novel superporous agarose anion exchangers have been prepared, differing with respect to bead diameter, superpore