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BACKGROUND: Several widely used drugs have photosensitizing properties, and much research has been conducted to find associations between their use and the risk of developing cutaneous malignant melanoma (cM), basal cell carcinoma (BCC) or cutaneous squamous cell carcinoma (cSCC), often with conflicting results.OBJECTIVE: To assess whether the use of commonly prescribed photosensitizing drugs incr
Background Exclusive breastfeeding is essential for infant health, yet its practice varies across generations and cultures. Although the health benefits of breastfeeding have been well known for decades, the utilization of infant formula feeding worldwide and in Oman, in particular, continues to rise, most likely as a result of a lack of social support and the time limit faced by working mothers.
Background: In patients undergoing resection for pancreatic cancer, adjuvant modified fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) improves overall survival compared with alternative chemotherapy regimens. We aimed to compare the efficacy and safety of neoadjuvant FOLFIRINOX with the standard strategy of upfront surgery in patients with resectable pancreatic ductal adenocarci
Background: Decision-making regarding treatment limitations such as “Do not attempt resuscitation” (DNAR) orders for older patients has been found deficient. Patients ≥ 80 years with substantial comorbidity have little chance of surviving cardiac arrest, thus require thorough risk classification focusing on comorbidity and frailty. This study aimed to explore the degree of frailty, comorbidity and
Objectives: Studies have reported promising results regarding artificial intelligence (AI) as a tool for improved mammographic screening interpretive performance. We analyzed AI malignancy risk scores from two versions of the same commercial AI model. Materials and methods: This retrospective cohort study used data from 117,709 screening examinations performed in BreastScreen Norway 2009–2018. The
Background: Informal caregivers may experience high levels burden. Prior to COVID-19, loneliness and social isolation, and especially the discordance between them, were recognized for rapid aging-related cognitive decline. The COVID-19 has significantly increased social isolation and loneliness in caregivers. Thus, we aimed to explore the variables that were associated with higher care burden amon
Introduction and Objectives: To compare pilot cohorts of men scheduled for radical prostatectomy imaged with novel antibody conjugates: Cohort 1 (111In-J591) single photon emission tomography (SPECT) or Cohort 2 (89Zr-J591) positron emission tomorgraphy (PET).Methods: 1) Cohort 1: Eight patients with abnormal digital rectal exam and biopsy proven prostate cancer were injected intravenously with tw
In this thesis, a microfluidics platform with high-speed imaging system was built to investigate gas-liquid flow in single microchannel and interfacial instability in porous media with microchannel network:The mass transfer of slug flow in the rectangular and square microchannels was experimentally studied by using water as liquid phase and CO2 as gas phase. Depending on flow rates, flow patterns
Aims: Repeated risk assessments and treatment patterns over long time are sparsely studied in chronic thromboembolic pulmonary hypertension (CTEPH); thus, we aimed to investigate changes in risk status and treatment patterns in incident patients with CTEPH over a 5 year period. Methods and results: Descriptive and explorative study including 311 patients diagnosed with CTEPH 2008–2019 from the Swe
Background and Aims: Substance use disorder (SUD) is related to widespread adverse consequences, including higher suicidality. Shared genetic liability has been demonstrated between SUD and suicidality. Here, we measured the factors that contribute to increased risk of non-fatal suicide attempt among individuals with SUD by focusing upon aggregate genetic risks and both childhood and past-year env
Objective: To develop a standardized sonographic evaluation and reporting system for Cesarean scar pregnancy (CSP) in the first trimester, for use by both general gynecology and expert clinics. Methods: A modified Delphi procedure was carried out, in which 28 international experts in obstetric and gynecological ultrasonography were invited to participate. Extensive experience in the use of ultraso
Objectives: We explored the prevalence of health complaints subjectively associated with static magnetic field (SMF) and acoustic noise exposure among MR radiographers in Sweden, using CT radiographers as a control group. Additionally, we explored radiographers’ use of strategies to mitigate adverse health effects. Methods: A cross-sectional survey was sent to all hospitals with MR units in Sweden
The aim of this thesis has been to investigate self-diffusion behavior of host-guest complex, microemulsion and polymer solution. Pulsed Field Gradient NMR (PFG-NMR) was shown to provide detailed molecular information in all system studied. The general strategy was to measyre the diffusivities of the species and from there get molecular insight into the aggregation and dynamics of the system.
Sedan 1970-talet har antalet rapporterade cancerfall dubblerats, dels på grund av förändrade levnadsvanor och dels på grund av bättre screeningmetoder som upptäcker cancern i tidigt skede. Tidig upptäckt av cancern i kombination med utvecklad cancerbehandling har bidragit till att risken för att avlida av cancer har minskat. Cancerbehandling sker huvudsakligen genom operation, strålbehandling elleAim: The tomotherapy system offers two radiation techniques, TomoHelical (TH) and TomoDirect (TD). The aim of this master thesis was to evaluate TD as a treatment alternative mainly by comparing TD treatment plans with 3DCRT plans and comparing TD plans with TH plans, separately, in the thoracic and abdominal regions. An additional aim was to examine if the current patient specific quality control
Traditionally hydraulic actuators has been the primary choice in modern submarines due to their strength and reliability. In recent years many commercial and military vehicles have switched to electromechanical alternatives, as they are generally more energy efficient and have superior controllability. These are two attributes valued in a submarine, hence an investigation was carried out to assess
Objective: To describe the clinical and ultrasound characteristics of serous and mucinous cystadenomas in the adnexa. Methods: This was a retrospective international multicenter study. Using the International Ovarian Tumor Analysis (IOTA) database, patients with a histological diagnosis of serous or mucinous cystadenoma who had undergone preoperative ultrasound examination between 1999 and 2016 (I
Background: Antithrombotic treatment might affect bleeding symptoms, identification of bleeding source and treatment for patients with acute gastrointestinal bleeding. This study aims to investigate possible differences in initial bleeding symptoms, identified bleeding site and treatment of patients with or without antithrombotic medication admitted for gastrointestinal bleeding. Methods: All cons
The Purpose of this study is to analyze possible differences in the conditions of labor market entry for young people in Swedish High Schools. Differences in conditions for students are interesting to study with the knowledge that youth unemployment in Sweden today is quite high compared to many other European countries and that young people generally have a weaker position in the labor market tha
Background Anorexia nervosa is associated with high personal and financial costs for sufferers, carers and society in general, but little is known about the long-term health economic burden. Aims To examine healthcare utilisation, social assistance, sick leave and disability pension in individuals with anorexia nervosa over a period of 30 years. Method Fifty-one individuals with adolescent-onset a
Nepal ligger i ett av världens mest jordbävningsutsatta områden, och jordbävningen i Gorkha 2015 visade tydligt hur sårbara murverksbyggnader utan ingenjörsmässig dimensionering kan vara. I återuppbyggnadsarbetet har interlocking Compressed Sta- bilised Earth Blocks (CSEB) lyfts fram som ett möjligt alternativ till traditionellt murverk av bränt lertegel. Detta eftersom systemet både kan vara mer Nepal is located in one of the most seismically active regions in the world, and the 2015 Gorkha earthquake clearly demonstrated the vulnerability of non-engineered masonry buildings. In the reconstruction efforts following the earthquake, interlocking Com- pressed Stabilised Earth Blocks (CSEB) have been highlighted as a potentially more seismically robust and at the same time more sustainable al
