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Acute Pancreatitis. Biomarkers and radiology assessment

Background: Acute pancreatitis (AP) is a common and potentially severe disease. Early identification of severity grade is crucial for the outcome of the patient. For study approaches and comparison of inter-institutional data the AP patients need to be uniformly classified.The aims of this thesis were to investigate the early stratifiation capacity of biomarkers in AP and to assess the morphologic

How does the job applicants' ethnicity affect the selection process? : Norms, Preferred competencies and expected fit

Denna avhandling studerar faktorer som påverkar rekryterare då de skall välja bland jobbsökande med olika etnisk bakgrund. Generellt förväntades att de sökandes etnicitet skulle påverka rekryterares val och deras uppfattning om vad som är viktigt att ta fasta på hos en arbetssökande person, och att detta kan ske i olika faser av rekryteringsprocessen.Studie 1 visade att företagsnormer påverkar rekThe present thesis aimed to study different factors influencing recruiters when recruiting from an applicant pool with applicants from an ethnic ingroup and outgroup. Ethnicity was predicted to influence recruiters’ perception and behaviour in different phases during recruitment. Study I demonstrated that company norms affect recruiters’ perception of what an employee should be like. Company norms

Differences in biomarkers of cartilage matrix turnover and their changes over 2 years in adolescent and adult volleyball athletes

BACKGROUND: This study aimed the feasibility to assess longitudinal changes in biomarkers of cartilage turnover and to determine their relationship with patient-rated outcomes over 2 years in volleyball athletes.METHODS: Thirty-seven athletes were studied: 18 adolescents (age 15.9 ± 0.64 years) in a 2-year intensive volleyball training program and 19 adult recreational volleyball players (age 46.5

Central retinal vein occlusion in younger Swedish adults : Case reports and review of the literature

Purpose: To investigate associated systemic diseases, other conditions, visual outcome, ocular complications and treatment in Swedish patients younger than 50 years with central retinal vein occlusion (CRVO) and reviewing the literature. Methods: Twenty-two patients with CRVO, younger than 50 years, were examined with full-field electroretinography (ERG) within 3 months after a thrombotic event, o

Conflict frequency as predictor of negative acts and being a target or perpetrator of bullying two years later.

Conflict in organizationsBullying and harassmentTh-SYM-655-6Conflict frequency as predictor of negative acts and being a target or perpetrator of bullying two years later.A. Hogh 1,*, E. G. Mikkelsen 2, Å. M. Hansen 3 4, R. Persson 5, P. M. Conway 61Department of Psychology, University of Copenhagen, Copenhagen, 2Gemzoe Consult, Aarhus, 3Public Health, UNIVERSITY OF COPENHAGEN, 4National Research Main Abstract Content: Purpose To investigate the association between conflict frequency and bullying at T1 and T2, moderation of individual conflict management styles and mediation of negative acts. Methodology Data from the Workplace Bullying and Harassment cohort (2006-2008) were analysed cross-sectionally (n=3363) and longitudinally (n=1664). Measures: conflict frequency; three individual con

High levels of circulating folate concentrations are associated with DNA methylation of tumor suppressor and repair genes p16, MLH1, and MGMT in elderly Chileans

Background: Changes in DNA methylation, one of the most studied epigenetic mechanisms, are considered an initial marker for early cancer detection. We evaluated how availability of dietary factors (folates and vitamin B12) involved in one-carbon metabolism may contribute to DNA methylation changes of cancer-related genes in human subjects. Methods: We studied, by pyrosequencing, the methylation of

Longitudinal changes in adolescents with TOF : Implications for care

Background We sought to identify predictors of change in right ventricular function and exercise capacity in adolescents following repair for tetralogy of Fallot. Methods and results We performed a longitudinal study with serial cardiac magnetic resonance imaging and/or exercise stress tests. Patients with interim intervention on the pulmonary valve were excluded. Paired t-test was used to detect

Thinking green, circular or bio : Eliciting researchers' perspectives on a sustainable economy with Q method

The continuous emergence of new ideas and terms simultaneously enables and impedes the advancement of sustainability, because of an increasingly complex conceptual landscape. This study aims at highlighting combinations of sustainability concepts (circular, green and bioeconomy) and of development models (growth, steady-state, degrowth) which selected researchers have considered priorities for pur

Functional Characteristics of Protein Stabilized Emulsions: Emulsifying Behaviour of Proteins in a Sonifier.

Protein stabilized emulsions made up of 40% soybean oil by weight and protein dispersions of 2.5% (w/w) protein content have been prepared in an ultrasonic device. The emulsifying apparatus was incorporated into a recirculating system, where power input and number of passes were varied. The food proteins studied were a soy bean protein isolate, a whey protein concentrate (WPC), and a sodium casein

Influence of personality traits on nueropsychological test performance in toxic encephalopathy cases and healthy referent subjects

The relationship between personality traits and cognitive performance was studied in two groups: men with symptoms and neuropsychological test results compatible with toxic encephalopathy (TE) and demographically similar healthy men (N=57 per group). Personality traits were assessed with the Karolinska Scales of Personality (KSP). The neuropsychological examination included 13 tests covering vario

Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients : an explorative analysis of a randomized trial

OBJECTIVE: Exposure to hyperoxemia and hypoxemia is common in out-of-hospital cardiac arrest (OHCA) patients following return of spontaneous circulation (ROSC), but its effects on neurological outcome are uncertain, and study results are inconsistent. METHODS: Exploratory post hoc substudy of the Target Temperature Management (TTM) trial, including 939 patients after OHCA with return of spontaneou

Studies on lexical inferencing and inter comprehension of Italian as a foreign language in a Swedish setting

This dissertation is a collection of three studies in which the main focus is on the role of Swedish L1 speakers’ background languages for the comprehension of written Italian at a lexical level. Italian is one of the foreign languages that Swedish pupils in upper secondary school can choose to study. Previous research on third language acquisition and the role of the background languages in the S

Combined production of biogas and ethanol at high solids loading from wheat straw impregnated with acetic acid: experimental study and techno-economic evaluation.

BackgroundProduction of ethanol and biogas from acetic acid-impregnated steam-pretreated wheat straw was investigated. The solid fraction after pretreatment was used at high solids concentrations to generate ethanol by simultaneous saccharification and fermentation (SSF). The residual streams were evaluated with regard to biogas production. The experimental results were used to perform a techno-ec

Analytical validation of a standardized scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicenter collaboration

Aims: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of interlaboratory variability has hampered its clinical utility. The International Ki67 in Breast Cancer Working Group has undertaken a systematic programme to determine whether Ki67 measurement can be analytically validated and standardised among lab

Management and outcome of muscle-invasive bladder cancer with clinical lymph node metastases. A nationwide population-based study in the bladder cancer data base Sweden (BladderBaSe)

Purpose: To investigate the clinical management and outcome of patients with muscle-invasive bladder cancer with clinical lymph node involvement, using longitudinal nationwide population-based data. Methods: In the Bladder Cancer Data Base Sweden (BladderBaSe), treatment and survival in patients with urinary bladder cancer clinical stage T2–T4 N + M0 diagnosed between 1997 and 2014 was investigate

Association Between Vitamin D, Frailty, and Progression of Frailty in Community-Dwelling Older Women

CONTEXT: Vitamin D (25OHD) is involved in many physiological functions that decline with age, contributing to frailty and increased risk for negative health outcomes. Whether 25OHD is a long-term risk marker for frailty over a longer time and whether it is consistent with advancing age is unclear. OBJECTIVE: To investigate the association between 25OHD and frailty in older women followed for 10 ye

Ether-free polyfluorenes tethered with quinuclidinium cations as hydroxide exchange membranes

We report on aryl ether-free 2,7-diphenylfluorene-based copolymers tethered with quinuclidinium (Qui) cations via hexyl spacers, prepared through superacid catalyzed Friedel Crafts polycondensation and quaternization reactions. The 2,7-diphenylfluorene monomers were prepared by Suzuki coupling and employed to increase polymer backbone stiffness. Corresponding copolymers and anion-exchange membrane

Characterization of presynaptic 5-HT receptors on adrenergic nerves supplying the bovine ovarian follicle

1. The effects of 5-hydroxytryptamine (5-HT) on contraction and release of [3H]-noradrenaline were investigated in vitro in bovine ovarian follicle strips. Using available selective agonists and antagonists, an effort was made to characterize the type of receptor mediating the inhibitory effect of 5-HT on neurogenic contraction and release of [3H]-noradrenaline by electrical field stimulation. 2.

Association of Immune Marker Changes with Progression of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma

Importance: Multiple myeloma is consistently preceded by monoclonal gammopathy of undetermined significance (MGUS). Risk models that estimate the risk of progression from MGUS to multiple myeloma use data from a single time point, usually the initial workup. Objective: To longitudinally investigate the alterations of serum immune markers with stable vs progressive MGUS. Design, Setting, and Partic

Quality of Life Improvements in Patients with Lymphedema After Surgical or Nonsurgical Interventions with 1-Year Follow-Up

Background: Lymphedema may impact patients' health-related quality of life (HRQoL). The purpose of this study was to evaluate HRQoL after two different treatments to the 12-month follow-up point. Methods and Results: Study participants were patients with moderate lymphedema in the upper or lower limb who attended a Swedish rehabilitation program (RP) undergoing conservative treatment, or those w