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Popular Abstract in Swedish Helicobacter pylori är en bakterie som orsakar såväl magkatarr, magsår som magsäckscancer. H. pylori producerar olika virulensfaktorer såsom enzymet ureas, ett cell vakuolbildande toxin (VacA), andra cytotoxiska proteiner (cagA eller pathogenicity island-associated proteins), flageller och adhesiner. För etablering av H. pylori infektion, måste dessa virulensfaktorer inHelicobacter pylori is a gastric pathogen which cause chronic type B gastritis and peptic ulcer disease. H. pylori produces virulence factors such as urease, vacuolating cytotoxin VacA, cag pathogenicity island-associated proteins, flagella and adhesins. These proteins interact with several host cell molecules such as sialylated cell surface glycoproteins, some of glycolipids and mucins. Glycosami

Popular Abstract in Swedish Avhandlingens syfte är att ge ett bidrag till att belysa hur olika teorier och modeller kan förklara den sociala, kulturella och psykologiska situation som en avgränsad grupp kvinnor med narkotikaproblem befinner sig i. I avhandlingen görs en ansats att integrera ett socialpsykologiskt perspektiv med ett kvinnoforskningsperspektiv och ett personlighetspsykologiskt perspThe purpose of this study was to systematically examine the social, cultural and psychological situation of a group of women with drug addiction, and to gain an understanding of it. Different theoretical perspectives were utilized in efforts to understand and explain why some young women start using drugs. The attempt was made to integrate a social psychological perspective with a perspective base

Eicosanoids are important for a wide range of physiological and pathophysiological processes.How their essential fatty acid precursors are absorbed and tissue distributed is not well charactherized. When given orally to rats, arachidonic acid (20:4) was retained in the small intestine to a larger extent than linoleic acid (18:2).More 20:4 than 18:2 was incorporated in phospholipids (PL) of the sma

Popular Abstract in Swedish Fokus i denna avhandling är en av de mest frekventa organisationsförändringarna i den offentliga sektorn under 1990-talet, införandet av resultatenheter. Det finns tre huvudsakliga anledningar till att studera resultatenheter. För det första eftersom resultatenheter förefaller bli ett bestående inslag i den framtida styrningen av den kommunala sektorn. För det andra harThe focus of this thesis is on the most widespread organizational change that the public sector has gone through during the 1990s: the introduction, implementation and continuous use of profit centers. There are three major reasons for studying profit centers. First, profit centers appear to have become a permanent element in the management of local government. Second, profit centers were used dif

Popular Abstract in Swedish Denna avhandling är en del av en prospektiv, longitudinell studie, som avser att studera sambandet mellan psykosociala faktorer och debuten och förloppet av barndiabetes. Diabetes är en av de vanligaste kroniska sjukdomarna hos barn i Sverige och antalet insjuknade ökar. Tillsammans med Finland har Sverige en av de högsta förekomsterna av barndiabetes i världen. SjukdomThis thesis is a part of a prospective multi-centre study concerning psychosocial aspects of importance for the onset and course of insulin-dependent diabetes mellitus (IDDM). The investigated population was all children with onset of IDDM in the participating clinics during 1988 and 1989. Of 79 diseased children, 67 participated in the study. To each child a healthy control child was chosen, 61 a

Objective: Uninterrupted sleep is of vital importance for restoration and regaining health. In intensive care units (ICUs) where recovering and healing is crucial, patients' sleep often is fragmented and disturbed due to noise from activities from oneself, other patients, and alarms. The aim of our study was to explore if sleep could be improved by modifying the sound environment in a way that is

We have previously shown that the presence of pancreatic enzymes in the gut lumen of exocrine pancreatic insufficient pigs influences blood glucose and insulin levels during an intravenous glucose tolerance test (IVGTT). The present study aims to highlight the effects of orally applied pancreatic-like enzymes on blood glucose and plasma insulin levels during an IVGTT in young intact pigs. Five, 7-

Computer-aided interpretation of electrocardiograms (ECGs) is widespread but many physicians hesitate to rely on the computer, because the advice is presented without information about the confidence of the advice. The purpose of this work was to develop a method to validate the advice of a computer by estimating the error of an artificial neural network output. A total of 1249 ECGs, recorded with

BACKGROUND: Workplace stressors, such as bullying, are strongly related to subsequent long-term sickness absence, but little is known of the possible physiological mechanisms linking workplace stressors and sickness absence. The primary aim of this study was to investigate to what extent cortisol levels were associated with subsequent sickness absence and if cortisol mediated the association betwe

OBJECTIVE - Ketosis-prone diabetes (KPD) is an emerging, heterogeneous syndrome. A sound classification scheme for KPD is essential to guide clinical practice and pathophysiologic studies. Four schemes have been used and are based on immunologic criteria, immunologic criteria and insulin requirement, BMI, and immunologic criteria and β-cell function (Aβ classification). The aim of the present stud

BackgroundThe role of inflammation in Alzheimer’s disease (AD) and other cognitive disorders is unclear. In a well-defined mono-center population, we measured cytokines and chemokines in paired serum and cerebrospinal fluid (CSF) samples. MethodsConsecutive patients with AD (n = 30), stable mild cognitive impairment (SMCI, n = 11), other dementias (n = 11), and healthy controls (n = 18) were inclu

The Lundby Study is a prospective mental health survey in a community population (N = 3563), in which data were collected in 4 waves of field-work between 1947 and 1997. We investigated gender differences during the follow-up in overall first incidence rates, ages of onset, and incidence by age of onset patterns, in different subtypes of depression. The overall incidence rate in females was higher

There is an assumption in current landscape preference theory of universal consensus in human preferences for moderate to high openness in a natural landscape. This premise is largely based on empirical studies of urban Western populations. Here we examine for the first time landscape preference across a number of geographically, ecologically and culturally diverse indigenous populations. Included

BACKGROUND: Blood phosphate levels are vulnerable to fluctuations and changes in phosphate levels are often neglected. The aim of this study was to evaluate whether deviations in phosphate levels correlate to higher 180-day overall mortality or morbidity. METHODS: Four thousand six hundred fifty-six patients with 19,467 phosphate values treated at the adult intensive care unit at Skåne University

Objectives: Dysglycemia and glycemic variability are associated with poor outcomes in critically ill patients. Targeted temperature management alters blood glucose homeostasis. We investigated the association between blood glucose concentrations and glycemic variability and the neurologic outcomes of patients randomized to targeted temperature management at 33°C or 36°C after cardiac arrest. Desig

This report aims to introduce, test and discuss a new method of measuring episodic memory in participants with highly restricted verbal abilities. Although an elicited/deferred imitation paradigm has already proposed a successful method of measuring this capacity in infants as young as 6 months old [Bauer, Patricia J. 2006. “Constructing a Past in Infancy: A Neuro-Developmental Account.” Trends in

Objective: One major issue in dynamic susceptibility contrast MRI (DSC-MRI) is to accurately determine contrast agent (CA) concentration, since T2* relaxivity in vivo is generally unknown and varies between blood and tissue. In this study, quantitative susceptibility mapping (QSM) was used for quantification of CA concentration. Materials and methods: A DSC-MRI protocol, including phase data acqui

BACKGROUND: A significant number of patients with primary hyperparathyroidism (pHPT) who are surgically treated have increased serum levels of intact parathyroid hormone (PTH) during long-term follow-up despite normocalcemia. The cause and significance of this finding remain to be established.METHODS: A total of 82 patients operated on for sporadic parathyroid adenoma were investigated before and

The objective of this study was to assess erysipelas incidence before and after liposuction treatment for patients suffering from post-mastectomy lymphedema. A prospective cohort study of 130 patients at Skåne University Hospital in Malmö, Sweden with postmastectomy arm lymphedema, who had poor outcomes from prior conservative treatment and clinical signs of subcutaneous adipose tissue hypertrophy