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Background: Mutations in the PRSS1 gene explain most occurrences of hereditary pancreatitis (HP) but many HP families have no PRSS1 mutation. Recently, an association between the mutation N34S in the pancreatic secretary trypsin inhibitor (SPINK1 or PSTI) gene and idiopathic chronic pancreatitis (ICP) was reported. It is unclear whether the N34S mutation is a cause of pancreatitis per se, whether

Objective To study, in a large cohort, the association between the use of anti-asthmatic drugs during pregnancy and pregnancy complications. Methods Using the Swedish Medical Birth Register, we identified 24,369 women who reported the use of anti-asthmatic drugs in early pregnancy and 7778 women who were prescribed such drugs later during pregnancy by antenatal care system centres, during the peri

The phase behavior of a thermoseparating cationic hydrophobically modified ethylene oxide polymer (HM-EO) containing tertiary amines has been investigated at different pH, salt and sodium dodecyl sulfate (SDS) concentrations, in order to find a water/HM-EO two-phase, system suitable for protein partitioning. The used polymer forms micellar aggregates that can be charged. By changing pH and SDS con

Objectives: With the introduction of sildenafil citrate (VIAGRA (TM)), the concept of phosphodiesterase (PDE) inhibition has gained tremendous interest in the field of urology. Cyclic nucleotide second messengers cGMP and cAMP have been assumed to be involved in the control of the normal function of the prostate. The aim of the present study was to evaluate by means of immunohistochemistry the exp

Measurements in a road tunnel in Stockholm, Sweden give the real-world traffic emission factors for a number of gaseous and particle pollutants. These include 49 different polycyclic aromatic hydrocarbons (PAH), CO, NOX, benzene, toluene, xylenes, aldehydes, elements and inorganic/organic carbon contained in particles, the sub-micrometer aerosol number size distribution, PM2.5 and PM10. The exhaus

OBJECTIVE: To study the effect of postoperative thyroxine on the volume of the thyroid remnant after lobectomy for benign nontoxic goitre. DESIGN: Prospective, randomised study. SETTING: University hospital, Sweden. SUBJECTS: 50 consecutive patients who underwent lobectomy for benign non-toxic goitre. INTERVENTIONS: Patients were randomised postoperatively to take thyroxine 0.1 mg or placebo daily

BACKGROUND: The characteristic feature of Goodpasture disease is the occurrence of an autoantibody response to the noncollagenous domain of the alpha3 chain of type IV collagen [alpha3(IV)NC1] in the alveolar and glomerular basement membrane. These antibodies are associated with the development of a rapidly progressive glomerulonephritis, with or without lung hemorrhage, whereas autoantibodies spe

BACKGROUND: Human exposure to persistent organic pollutants (POPs) is ubiquitous and found in all individuals. Studies have documented endocrine disrupting effects and impact on reproduction. The aim of the present study was to compare the level of xenoestrogenic activity in serum of groups with varying POP exposure, and to evaluate correlations to the POP biomarkers, 2,2',4,4',5,5'-hexachlorobiph

We aimed to study trends in gender-related differences in incidence, and prevalence for tong-term oxygen therapy due to chronic obstructive pulmonary disease. Another aim was to study survival after onset of oxygen therapy. Prospectively followed were 5689 Swedish patients, who were prescribed oxygen therapy because of chronic obstructive pulmonary disease from 1987 to 2000. The annual incidence o

Aim. Older people's views of prioritization in health care. The applicability of an interview study. Old age has been stated as a criterion for prioritization in health care, although older people are seldom asked for their opinions. The aim of this pilot study was to investigate the applicability of a questionnaire as a base for an interview study to explore older people's experiences and views o

OBJECTIVES: To evaluate if patients with acute lacunar syndromes have acute lacunar infarcts or other types of cerebral lesions on diffusion-weighted MRI. METHODS: Patients with acute lacunar syndromes underwent echo-planar diffusion MRI of the brain within 3 days after stroke onset. Localization and size of lesions with hyperintense signal were determined, compared with clinical characteristics a

OBJECTIVE. The goal was to examine whether being a victim of bullying was associated with medicine use, taking into account the increased prevalence of physical and psychological symptoms. METHODS. The study population included all students in grades 5, 7, and 9 (mean ages: 11.6, 13.6, and 15.6 years, respectively) in a random sample of schools in Denmark (participation rate: 88.5%; N = 5205). The

The growth rates and motility of dinoflagellates were studied in the field in the presence or absence of UVB radiation, as well as in the laboratory under artificial radiation conditions. Photosynthetically active radiation (PAR, 400–700 nm) and UVB radiation showed large variations due to cloud cover and seasonal changes in natural daylight. In Swedish coastal water, UVB radiation was attenuated

In northern Patagonia, macrolichens form species-rich and abundant epiphytic communities in southern beech forests. Five of the most abundant lichen species in the litter were selected in order to study mass loss rate and changes in mineral composition over time. The litter bag method was applied to the foliose lichens Pseudocyphellaria faveolata, Pseudocyphellaria flavicans, Nephroma antarcticum,

A method with low MDL (minimum detection limit) was developed for analysis of carbon (C), nitrogen (N) and oxygen (O) in aerosol samples collected on an organic backing. An accelerator-produced beam of protons interacting with the sample and the detection of elastically scattered protons (PESA; particle elastic scattering analysis) and emitted X-rays (PIXE; particle-induced X-ray emission) were th

Popular Abstract in Swedish Döva barns begreppsbildning i matematik Denna studie tar utgångspunkt i frågan varför många döva barn har svårt att lära sig matematik. Studiens syfte är att belysa döva barns begreppsbildning i ämnet matematik genom att beskriva hur några döva barn uttrycker sig och agerar på väg mot förståelse av två centrala matematiska begrepp, nämligen multiplikation med heltal ochThe question why deaf children have difficulties in learning mathematics is the basis of this study. The aim of the study is to illuminate deaf children’s concept formation in mathematics by describing how some deaf children express themselves and act on their way towards understanding two basic concepts, the concept of multiplication with whole numbers and the concept of length. Theories develope

To explore the spatial variation of the soil microbial community within a mixed Norway spruce-birch stand, and to test if the spatial patterns of the microbial community are related to the position of trees, we sampled the forest floor at two spatial scales and used the phospholipid fatty acid (PLFA) patterns as indicators of the microbial community structure. Of the 32 most common PLFAs, 20 (62%)

BACKGROUND: Development of proximal and distal colorectal cancers involve partly different mechanisms associated with the microsatellite instability (MSI) and the chromosomal instability (CIN) pathways. Colorectal cancers in patients under 50 years of age represent about 5% of the total number of tumors and have been associated with an increased frequency of MSI tumors. However, MSI and CIN may pl

The chromosomal location of six barley genes was determined by Southern blot experiments using wheat strains which contained the short or long arm from one of the seven barley chromosomes. The genes analysed encode enzymes that are required for chlorophyll and heme synthesis. Glutamyl-tRNAGlu synthetase, glutamate 1-semialdehyde 2,1-aminotransferase and glutamyl-tRNAGlu reductase are common to bot

Commercial decabromodiphenyl ether (DecaBDE) is commonly used as a flame retardant in different electrical and textile applications. It is also used in the production of flame-retarded rubber compound. DecaBDE is the major technical polybrominated diphenyl ether (PBDE) in use today and consists mainly of decabromodiphenyl ether(BDE209). PBDEs, including BDE-209, are well-known environmental pollut