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Migration strategy and winter area use of common swift (Apus apus) breeding in the Netherlands – using combined GeoLight and FlightR approach

Migration is an adaptation for birds to exploit the resources that change temporally and spatially. The recent development of miniature light level geolocators has revealed this previously poorly known aspect of birds. From light intensity data together with time recorded by geolocators, we can infer the positions of the birds, i.e. latitudes and longitudes, using a threshold method or a curve-fit

An analysis of the IgE-encoding transcriptome in response to Phl p 2 in individuals lacking stereotypical immune response

Antikroppar är en samling av proteiner som spelar en viktig roll i människans immunförsvar. De kan identifiera speciella strukturer hos andra molekyler (antigen) och binda sig till dessa. Varje antikropp binder endast en typ av antigen. Immunförsvaret består dock av en flora av antikroppar och kan därmed bekämpa en mängd smittämnen som bakterier och virus. Antikropparna delas in i olika grupper beIgE is responsible for type 1 mediated allergic reactions, affecting an increased part of the European population. Even though a large part of the population is affected, further being an economical burden for society, little is known about the human IgE repertoire. Variation in antibodies are mainly found in antibody variable domains, and gained understanding of the IgE repertoire can be obtained

The balance between under- and over-immunosuppression after heart transplantation with emphasis on acute cellular rejection and chronic kidney disease. Experiences from Skåne University Hospital in Lund 1988-2010

Background and aims:Heart transplantation (HT) constitutes the ultimate treatment choice for end-stage heart failure. Following HT, patients require life-long immunosuppressive treatment to prevent allograft rejection. Although survival has steadily increased over the last few decades, issues related to under- and over-immunosuppression remain common and continue to represent one of the most impor

Psychometric evaluation and refinement of the Prenatal Attachment Inventory

Objective: To explore the underlying structure of the Prenatal Attachment Inventory (PAI) and to assess the psychometric properties of the subscales. Background: The establishment of the mother-fetus relationship is an important developmental task for successful adaption to pregnancy, with implications for the well-being of mother and child. The PAI was developed to measure the relationship betwee

Perceived and measured indoor climate in new-family buildings including identifying technical deficiencies

When new buildings are constructed the indoor climate for the first period may differ from the one after some years due to various factors, for example may the emissions from the building materials be higher, possibly affecting the air quality, and the balancing of the technical systems; the mechanical supply and exhaust system and heating may not be completely finished. The perceived indoor clima

Inferring dispersal across a fragmented landscape using reconstructed families in the Glanville fritillary butterfly

Dispersal is important for determining both species ecological processes, such as population viability, and its evolutionary processes, like gene flow and local adaptation. Yet obtaining accurate estimates in the wild through direct observation can be challenging or even impossible, particularly over large spatial and temporal scales. Genotyping many individuals from wild populations can provide d

Regional differences in air velocity of microclimate inside clothing and bellows effect

Despite of a crucial role of microclimate inside clothing in thermal comfort, air velocity inside clothing has been hardly reported, ever since Lewis et al (1969) demonstrated that air velocity of the still air layer on the naked human body was 0.25 m/s using colour schlieren cinephotography. This study was aimed to investigate the air velocity of microenvironment inside clothing and the bellows e

Transplant of full-thickness embryonic rabbit retina using pars plana vitrectomy

PURPOSE: To develop an improved surgical technique making full-thickness retinal transplant possible, thereby achieving a normal laminated transplant with minimal rosette formation.METHODS: A total of 23 rabbits underwent vitrectomy, retinotomy, and subsequent subretinal transplant of a complete embryonic neuroretina using a specially crafted glass cannula. Of the 23 animals, 15 received a prenata

Predictors of changes in gait performance over four years in persons with late effects of polio

BACKGROUND: Reduced gait performance is common in persons with late effects of polio. OBJECTIVE: To identify predictors of change in gait performance over four years in persons with late effects of polio. METHODS: Gait performance was assessed annually in 51 ambulatory persons (mean age 64 years, SD 6) by the Timed "Up & Go" (TUG), Comfortable and Fast Gait Speed (CGS, FGS), and 6-Minute Walk

Increased frequency of retinopathy of prematurity over the last decade and significant regional differences

Purpose: Retinopathy of prematurity (ROP) causes childhood blindness globally in prematurely born infants. Although increased levels of oxygen supply lead to increased survival and reduced frequency of cerebral palsy, increased incidence of ROP is reported. Methods: With the help of a Swedish register for ROP, SWEDROP, national and regional incidences of ROP and frequencies of treatment were evalu

Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor-γ (PPARγ) are disrupted by retinal disease-associated mutations

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the nuclear receptor (NR) superfamily of transcription factors. We assessed the ability of these NRs to form heterodimers with other members of the human NRs representing all major subgroups. The TLX ligand-binding domain (LBD

The clinical features of alcohol use disorders in biological and step-fathers that predict risk for alcohol use disorders in offspring

Given that Alcohol Use Disorder (AUD) is clinically heterogeneous, can we, in a large epidemiological sample using public registries, identify clinical features of AUD cases in biological and step-fathers that index, respectively, genetic and familial-environmental risk for AUD in their offspring? From all father-offspring pairs where the father had AUD and the offspring was born 1960–1990, we ide

An ethnographic observation study of the facilitator role in an implementation process

BackgroundEven though the importance of a facilitator during an implementation process is well described, the facilitator’s role is rarely problematized in relation to the organizational context in terms of power and legitimacy; themes which have recently been brought to the fore when studying change in health care organizations. Therefore, in this article, we present a qualitative study with the

Analysis and exploitation of resource efficiency potentials in industrial small and medium-sized enterprises – Experiences with the EDIT Value Tool in Central Europe

Material and energy costs represent about 50% of the operating costs incurred by European small and medium-sized enterprises (SMEs). Although the potential for resource efficiency improvements is high, the necessary awareness and human resource capacities to explore this potential are limited. Existing tools for exploration of resource efficiency improvement potentials have several shortcomings: t

Enteral Pancreatic-like Enzymes of Microbial Origin affect Insulin Release during an Intravenous Glucose Tolerance Test

We have previously shown that the presence of pancreatic enzymes in the gut lumen of exocrine pancreatic insufficient pigs influences blood glucose and insulin levels during an intravenous glucose tolerance test (IVGTT). The present study aims to highlight the effects of orally applied pancreatic-like enzymes on blood glucose and plasma insulin levels during an IVGTT in young intact pigs. Five, 7-

A confident decision support system for interpreting electrocardiograms

Computer-aided interpretation of electrocardiograms (ECGs) is widespread but many physicians hesitate to rely on the computer, because the advice is presented without information about the confidence of the advice. The purpose of this work was to develop a method to validate the advice of a computer by estimating the error of an artificial neural network output. A total of 1249 ECGs, recorded with

The associations between workplace bullying, salivary cortisol, and long-term sickness absence : a longitudinal study

BACKGROUND: Workplace stressors, such as bullying, are strongly related to subsequent long-term sickness absence, but little is known of the possible physiological mechanisms linking workplace stressors and sickness absence. The primary aim of this study was to investigate to what extent cortisol levels were associated with subsequent sickness absence and if cortisol mediated the association betwe

Accuracy and predictive value of classification schemes for ketosis-prone diabetes

OBJECTIVE - Ketosis-prone diabetes (KPD) is an emerging, heterogeneous syndrome. A sound classification scheme for KPD is essential to guide clinical practice and pathophysiologic studies. Four schemes have been used and are based on immunologic criteria, immunologic criteria and insulin requirement, BMI, and immunologic criteria and β-cell function (Aβ classification). The aim of the present stud

Reduced cerebrospinal fluid concentration of interleukin-12/23 subunit p40 in patients with cognitive impairment

BackgroundThe role of inflammation in Alzheimer’s disease (AD) and other cognitive disorders is unclear. In a well-defined mono-center population, we measured cytokines and chemokines in paired serum and cerebrospinal fluid (CSF) samples. MethodsConsecutive patients with AD (n = 30), stable mild cognitive impairment (SMCI, n = 11), other dementias (n = 11), and healthy controls (n = 18) were inclu