Filtyp
Low bone mineral density (BMD) is a risk factor for fractures and much of the fracture preventive effort today is devoted to preventing low BMD. Physical activity (PA) has been described as one of the best strategies to optimize skeletal development in the growing child. However, most exercise intervention studies in children have involved the use of volunteers and specifically designed high impac
Background: Perinatal asphyxia is a major cause of mortality and morbidity. To date there are no reliable methods to detect which infants will develop brain damage after asphyxia insult. We investigated whether measurements of urine levels of S100B in asphyxiated full-term newborns maybe a useful tool for early detection of post-asphyxia brain damage. Methods: A prospective study of 38 infants wit
Background: The combination of the new high sensitivity troponin T (hsTnT) assays and copeptin, a biomarker of endogenous stress, has been suggested to have the potential of early rule-out of acute coronary syndrome (ACS). The aim of this study was to examine the ability of this combination to rule out ACS in patients presenting with chest pain and to compare the diagnostic performance to hsTnT al
This study investigated genetic causes of Parkinson's disease (PD) and parkinsonism in southern Sweden. The extensive Lister Family with parkinsonism caused by duplications and triplications of the gene for alpha-synuclein (SNCA) was studied. Clinical, genetic and genealogical data were compiled and evaluated. Thirty-five family members with parkinsonism were identified. They share a characteristi
Popular Abstract in Swedish Introduktion: Validitet handlar enkelt uttryckt om överensstämmelse med sanningen eller exempelvis om ett instrument mäter det som är avsett. Validitet kan också ses som ett mer komplext begrepp, innefattande aspekter som nytta, relevans, värderingar och sociala konsekvenser. Validitet förutsätter reliabilitet som är ett mått på tillförlitlighet, noggrannhet eller reproAbstract Introduction: Validity is important at different levels in psychiatry. Valid structured instruments are important aids in screening and diagnostics, in both research and clinical practice. An aim of the diagnostic procedure is to yield valid diagnoses. Ultimately, the validity of structured instruments (non-empirical) and clinical diagnoses depends on the validity of the diagnostic class
Objectives Nuchal translucency (NT) screening increases antenatal detection of Down syndrome (DS) compared to maternal age-based screening. We wanted to determine if a change in policy for prenatal diagnosis would result in fewer babies born with DS. Methods A total of 39572 pregnant women were randomized to a scan at 12-14 gestational weeks including NT screening for DS (12-week group) or to a sc
Background: Little is known about the relationships of circulating levels of biomarkers of cartilage degradation with biomechanical outcomes relevant to knee osteoarthritis (OA) or biomarker changes following non-pharmacological interventions. The objectives of this exploratory, pilot study were to: 1) examine relationships between biomarkers of articular cartilage degradation and synthesis with m
Populärvetenskaplig sammanfattning: Skåne är till stor del täckt av sedimentära, avlagrade bergarter t.ex. sandsten och kalksten, samt mycket yngre istidsavlagringar. Den kristallina berggrunden i Skåne utgör grunden för sedimenten och bildades huvudsakligen för mer än 1200 miljoner år sedan. Denna berggrund är bara synlig i de stora nordvästriktade horstar (åsar), som utgör ett markant drag i SkåThe Precambrian crystalline basement in Skåne only outcrops in the large NW striking Horsts that are roughly parallel to the Tornquist Zone. In the south-easternmost part of the Linderödsåsen Horst in SE Skåne, the Stenshuvud porphyritic granitoids previously considered to be Palaeoproterozoic volcanic rocks, have been recently dated to 1458 Ma. This indicates that these rocks are coeval with the
Accessibility is something often taken for granted in our society, but it is a necessity for people with disabilities. Railway stations are a public place and are often a connecting point for several modes of transport. Design of railway stations in terms of accessibility for persons with disabilities is governed by several national and international governing documents. The purpose of this thesis
Syftet med denna studie är att utreda möjligheterna för Öresundskraft AB att utvinna marin förnyelsebar energi från norra Öresund. Studien genomförs i två delar där Öresunds fysikaliska egenskaper samt marina krafttekniker kartläggs i den första för att sedan analysera den möjliga miljöpåverkan från de alternativen som kan vara intressanta i Öresund. De marina energitekniker som studerades var OTEThe purpose of this study is to determine the possibilities for Öresundskraft AB to derive marine renewable energy from northern Öresund, the sound between Sweden and Denmark. The physical properties of the sound, such as temperature, current speed, wave height, salinity gradients, bathymetry, are researched as well as which technologies are present in the current marine renewable energy market. T
Building in a manner that minimizes environmental impact has become a major part of the construction industry. Despite increased knowledge in this area the development is moving slowly. The purpose of this thesis is to give the reader an idea of the approach to green construction of civil engineering. The definition of a green tender is defined by the people who have been interviewed. The question
Populärvetenskaplig sammanfattning Den ökande urbaniseringen värden över och de hälsorisker som identifierats i samband med värmeböljor i städer, har medfört att det urbana klimatet blivit ett allt viktigare forskningsområde. Vindhastighet är en av de viktigaste parametrarna när det gäller att beräkna lokala klimatvariationer och bedöma eventuella hälsorisker. En enkel beräkningsmetod för vind kanWind is a complex phenomenon and a critical factor in assessing climatic conditions and pedestrian comfort within cities. This master’s thesis attempts to quantify and model the relationship between near ground wind speed and urban geometry using two-dimensional raster data and variable selection methods based on Multiple Linear Regression. A simple regression model can be implemented in a Geogra
Sedan sent 1800-tal har strålterapi använts för behandling av cancer. 50% av alla cancerpatienter blir någon gång behandlade med strålterapi, som är en avancerad teknik med många olika steg för att uppnå den slutgiltiga behandlingsplanen. Patienten börjar sin strålbehandlingsresa med att bli diagnosticerad och får sin behandling ordinerad. Efter detta startar förberedelserna inför strålbehandlingeBackground and purpose: Magnetic resonance imaging (MRI) only radiotherapy has, due to superior soft tissue contrast of MRI and the possible reduction of systematic uncertainties, grown into a promising technique. The purpose of this work is to investigate parts of an MRI only workflow with synthetic computed tomography (sCT) images generated from MRI. This was done through investigation of treatm
In this 24-month follow-up of a phase II study in patients with castration-resistant prostate cancer (CRPC) and bone metastases, radium-223 (4 injections of 50 kBq/kg every 4 weeks [n = 33]) improved median overall survival vs. matching placebo (n = 31) (65.3 vs. 46.4 weeks, respectively; log-rank P = .056), with no long-term safety concerns. Data suggest that treatment of bone disease with radium
We have found a new source of information about what lies beneath the Kalahari sands. The Kheis and Rehoboth Provinces of southern Africa were thought to be underlain by either an similar to 1800 Ma orogenic belt, or a northern branch of the similar to 1200 Ma Namaqua-Natal Province. Glacial diamictites of the Permocarboniferous Dwyka Group exposed at Rietfontein west of the Kalahari sands carry c
In times of increased environmental awareness, there exists a desire to not only build new environmentally friendly and renewable power generating units, but also to increase the efficiency of all existing technology. Wind power is such a renewable and environmentally friendly technology. Wind turbines and wind power have made giant leaps in the world in the past years, with an almost exponential
In times of increased environmental awareness, there exists a desire to not only build new environmentally friendly and renewable power generating units, but also to increase the efficiency of all existing technology. Wind power is such a renewable and environmentally friendly technology. Wind turbines and wind power have made giant leaps in the world in the past years, with an almost exponential
Almost 2 million people are living in Islamabad, significant number of workforce commute from neighboring areas and other parts of the country. The city is facing restraint on natural resources due to increased urban migration coupled with rapid population growth. As a result, the city infrastructure facilities and living conditions are deteriorating. The problems associated with drinking water av
PARP14, a member of the PARP family that can modify target proteins with ADP-ribose has stimulated the interest of researchers as it is involved in a variety of diseases including cancer. While some structural and activity characterization has been conducted, it has not been yet expressed and purified as a single molecule, instead it was examined in small constructs that include several of its dom
Stjärnströmmar är strömmar av stjärnor som har blivit ryckta ur antingen klotformiga stjärnhopar eller dvärggalaxer, som är i omloppsbana rund mer massiva galaxer. Forskare har hittat dessa stjärnströmmar runt vår galax Vintergatan. Exempelvis Sagittarius strömmen, som formas från dvärggalaxen Sagittarius, och Palomar 5 strömmen, som bildas av en klotformig stjärnhop. Strömmarna har också observerStellar streams are probes of the properties of their host potentials, giving clues about the host's shape, mass and substructure. There are several observed stellar streams both around the Milky Way and around external galaxies, and they are studied thoroughly. However, the impact of (i) the properties of the progenitor cluster or dwarf galaxy that form the streams, of (ii) the streams' o
