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Although the direction of loads applied to the proximal human femur is unpredictable during sideways fall, most in vitro and numerical simulations refer to a single loading condition (15° internal rotation; 10° adduction), which has been anecdotally suggested in the 1950s. The aim of the present study was to improve in vitro simulations of sideways falls on the proximal femur. An in vitro setup w
persson e.k., fridlund b., kvist l.j. & dykes a.-k. (2010) Mothers' sense of security in the first postnatal week: interview study. Journal of Advanced Nursing. ABSTRACT: Aim. This paper is a report of a study of factors which influence mothers' sense of security during the first postnatal week. Background. Mothers' sense of security the first postnatal week is not thoroughly elucidated in the
Introduction: In a cold,wet, or windy environment, cold exposure can be considerable for an injured or ill person. The subsequent autonomous stress response initially will increase circulatory and respiratory demands, and as body core temperature declines, the patient’s condition might deteriorate. Therefore, the application of adequate insulation to reduce cold exposure and prevent body core cool
Popular Abstract in Swedish Avhandlingens syfte var att kartlägga den vård vårdpersonalen i Sverige praktiserar när nyfödda barn är döende och dör; samt belysa hur svenska kvinnor upplevt hot om och förlust av sitt nyfödda barn och vården de erhållit; ett ytterligare syfte var att utforska muslimska kvinnors uppfattning om den i Sverige praktiserade neonatala vården i livets slut. De professionelThe aim was to describe the neonatal end-of-life practice and illuminate Swedish women's lived experiences of the threat and the reality of their neonate's dying and death as well as the care received. A further aim was to explore Muslim women's view of current Swedish neonatal-end-of-life care. In a questionnaire with close-ended questions 144 registered nurses described their experiences, behavi
Popular Abstract in Swedish Regleringen av esofagus och den nedre esofagussfinkterns motilitet har rönt intresse på grund av dess betydelse vid vissa sjukdoms-tillstånd såsom gastroesofageal reflux och akalasi. Den nedre esofagussfinktern har vidare använts som modell för farmakologiska och fysiologiska studier av viss typ av autonom neurotransmission, s k icke-adrenerg, icke-kolinerg (NANC) neuroThe inhibitory neuromuscular control of the human and cat lower oesophagus was investigated by morphological, functional, and biochemical methods. A supply of nerve fibres and myenteric cell bodies, containing nitric oxide synthase (NOS), haem oxygenase (HO)-2, vasoactive intestinal peptide (VIP), and pituitary adenylate cyclase activating peptide (PACAP) was observed. The highest density of nerve
Objectives: To evaluate how surgeon heterogeneity – the variation in outcomes between individual surgeons – influences functional and oncological outcomes after robot-assisted laparoscopic prostatectomy (RALP) and retropubic radical prostatectomy (RRP), and to assess whether surgeon heterogeneity affects the comparison between RALP and RRP. Patients and Methods: Laparoscopic Prostatectomy Robot Op
Primary immunodeficiencies (PIDs) are inherited disorders of the immune system with allogeneic hematopoietic stem cell transplantation (HSCT) as the only curative treatment in some of them. In case an HLA-matched donor is not available, HSCT from a haploidentical family donor may be considered. We compared the outcomes of HSCT from HLA-matched unrelated or related donors (MUDs or MRDs) and mismatc
Willow (Salix spp.) trees are commonly used in short rotation coppices (SRC) to produce renewable energy. However, these plants are also known to emit high concentrations of biogenic volatile organic compounds (BVOCs), which have a large influence on air quality. Many different clones of commercially used Salix varieties exist today, but only a few studies have focused on BVOC emissions from these
Approximately 20% of the population experience long-term pain. Women are generally more affected than men. Currently, pain researchers advocate a biopsychosocial perspective, which emphasises the importance of addressing psychological and social factors as well as biomedical ones in clinical practice. However, previous research shows that this holistic perspective is not always materialized in med
Recent studies have indicated a decline in sperm number in the western world during the past 50 years, sperm concentration changing from 113 to 66 millions per mL. Furthermore, significant geographical differences in male reproductive function have been observed. In Finland, the sperm concentration was found to be substantially higher than in Denmark. In parallel, the incidence of testicular cance
Popular Abstract in Swedish Denna avhandling beskriver olika optiska metoder för att diagnostisera cancer.En sådan metod är optisk spektroskopi (att med hjälp av ljus bestämma fysiska och kemiska egenskaper hos ett prov) som har används för att undersöka cancer i ögat. Avhandlingen omfattar vidare studier av optiska kontrastmedel tillverkade av nanokristaller (nano = en miljarddels meter), vilkas
Plants emit large quantities of isoprene and monoterpenes, the main components of global biogenic volatile organic compound (BVOC) emissions. BVOCs have an important impact on the atmospheric composition of methane, and of short-lived radiative forcing agents (e.g. ozone, aerosols etc.). It is therefore necessary to know how isoprene and monoterpene emissions have changed over the past and how fut
Background: The effectiveness of bronchial thermoplasty (BT) has been reported in patients with severe asthma, yet its effect on different bronchial structures remains unknown. Objective: We sought to examine the effect of BT on bronchial structures and to explore the association with clinical outcome in patients with severe refractory asthma. Methods: Bronchial biopsy specimens (n = 300) were col
Type 2 diabetes (T2D) is a complex disease with widespread physiological insults to the regulation of metabolic homeostasis, above all glycaemic regulation. The pathogenesis of T2D and its progression is broadly understood to be through a gradual decrease in peripheral insulin sensitivity, a compensatory rise in insulin secretion, and a gradual decline in beta-cell function, resulting in glycaemic
BackgroundPeople with intellectual disability have been found to have higher prevalence of psychiatric disorders than the general population. However, they do not seem to have a corresponding increase in psychiatric care utilization. The aim of the present study was to investigate psychiatric care utilization among older people with intellectual disability.MethodsWe used a cohort of people with in
Microtubule-disturbing drugs inhibit lysosomal trafficking and induce lysosomal membrane permeabilization followed by cathepsin-dependent cell death. To identify specific trafficking-related proteins that control cell survival and lysosomal stability, we screened a molecular motor siRNA library in human MCF7 breast cancer cells. SiRNAs targeting four kinesins (KIF11/Eg5, KIF20A, KIF21A, KIF25), my
Background: Faculty development roles are changing within organizations (Gibbs 2013). In previous research the expanding role in organizations as “Coming in from the margins” was described (Schroeder 2011). We studied how different levels of participation evolved within a research intense faculty with a complex organization and various educational programs.Summary of Work: The Centre was establish
