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In epidemiological and twin populations, prior interview studies have identified an externalizing spectrum of disorders. Could this be detected utilizing objective registry data? In 20,603 twin pairs from the Swedish Twin Registry, we obtained information from national medical, criminal and pharmacy records on drug abuse (DA), criminal behavior (CB) and alcohol use disorders (AUD). Multivariate tw
Measurement of haemoglobin (Hb) adducts from acrylamide (AA) and its metabolite glycidamide (GA) is a possibility to improve the exposure assessment in epidemiological studies of AA intake from food. This study aims to clarify the reliability of Hb-adduct measurement from individual single samples for exposure assessment of dietary AA intake. The intra-individual variations of AA- and GA-adduct le
Background: Mass screening could identify those with unrecognized celiac disease (CD), but the experience of being detected through screening and living with screening-detected CD should be explored before considering this as acceptable intervention. For this study we invited screening-detected adolescents to describe their experience living with screening-detected CD five years after diagnosis wi
Background: The number of new cases of type 1 diabetes mellitus (T1DM) has increased substantially in recent years and it is now one of the most common long-term endocrine disorders in childhood. In Sweden the child and family are hospitalised in accordance with the national guidelines for one to two weeks at diagnosis. The purpose of this study was to describe parents' perceptions of the educatio
Agricultural fertilisation increases crop yields but can cause environmental damage, thus reductions in inorganic fertiliser application have been advocated. Farmer usage of phosphate rock has declined over the last decade, which may lead to soil nutrient depletion that undermines future crop production. We investigated the long-term (55 years) effects of eight different inorganic fertiliser regim
Introduction The incidence of perforated peptic ulcer remains high in low and middle-income countries. Mortality can be significant, and early surgical management with careful evaluation of pre-operative risk factors is essential. The purpose of this study was to describe the clinical outcomes of surgical treatment for perforated peptic ulcer disease in Liberia and to explore risk factors for adve
Two single nucleotide polymorphisms (SNPs), rs4415084, and rs10941679 on chromosome 5p12 were associated with risk of breast cancer in a recent genome-wide association study (GWAS) of women of European ancestry. Both SNPs are located in a large high-LD region and the causal variant(s) are still unknown. We conducted a nested case-control study in a cohort of African American women to replicate and
nylinder p. (2011) Journal of Nursing Management19, 664-672 Perception of budgetary control: a study of differences across managers in Swedish public primary healthcare related to professional background and sex Background The composition of managers in Swedish public primary care centres has changed since the mid-1990s, favouring nurses and female managers. In parallel, health-care professionals
This study investigates the sensitivity of wastewater treatment plant (WWTP) model performance to the selection of one-dimensional secondary settling tanks (1-D SST) models with first-order and second-order mathematical structures. We performed a global sensitivity analysis (GSA) on the benchmark simulation model No. 2 with the input uncertainty associated to the biokinetic parameters in the activ
Objectives: To investigate the safety of a novel percutaneous circulatory support device during high-risk percutaneous coronary intervention (PCI). Background: The Reitan catheter pump (RCP) consists of a catheter-mounted pump-head with a foldable propeller and surrounding cage. Positioned in the descending aorta the pump creates a pressure gradient, reducing afterload and enhancing organ perfusio
BACKGROUND AND PURPOSE: The European Cooperative Acute Stroke Study (ECASS) III trial and Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) data were published in 2008. Riks-Stroke, the Swedish Stroke Register, was used to explore how thrombolysis in the 3- to 4.5-hour window has been spread in different hospitals and patient groups and what effec
Background: Prostate-specific antigen (PSA) based screening for prostate cancer (PCa) has been shown to reduce prostate specific mortality by 20% in an intention to screen (ITS) analysis in a randomised trial (European Randomised Study of Screening for Prostate Cancer [ERSPC]). This effect may be diluted by nonattendance in men randomised to the screening arm and contamination in men randomised to
Background: The risk of radiation-induced cancer has become a major concern with the increasing use of computed tomography (CT). Purpose: To compare image quality and radiation doses when decreasing X-ray tube peak kilovoltage (kVp) from 120 to 100 kVp in patients undergoing coronary CT angiography (CCTA). Material and Methods: Patients referred for evaluation of suspected coronary artery disease
Syftet med denna uppsats har varit att undersöka hur de senaste årens effektivisering inom socialpolitiken förändrat socialtjänsten och dess arbete, med utgångspunkt i Försäkringskassans ändrade regler. Försäkringskassans nya regler som trädde i kraft i juli 2008, har inneburit att sjukpenningen är begränsad till ett år. Regeringen har på så sätt implementerat arbetslinjen i sjukförsäkringen så tiThe purpose of this essay has been to investigate how the latest years of effectiveness in social politics has changed the social services and their work with starting point in the changed rules for social insurance in form of sickness leave. The new rules which emerged in July 2008 have meant that sickness benefits is limited to one year. This occurred in the time when labour market policy become
No one wants to be at the wrong place at the wrong time. No one wants to be accused of having committed a crime one hasn't committed. No one wants to be innocently convicted. According to the presumption of innocence (article 6.2. in ECHR) everyone who has been charged with a criminal offence shall be presumed innocent until proved guilty according to law. It is important that the judge rememb
Denna uppsats har via en rättsdogmatisk metod undersökt gällande rätt avseende nödvärn och nödvärnsexcess vid överfall. Den faktiska rättstillämpningen i underrätterna har inte berörts. Rätten till försvarsvåld gentemot brottsliga angrepp tillkommer dels den angripne, dels envar som befinner sig på platsen för angreppet. Denna rätt regleras i nödvärnsstadgandet i 24 kap. 1 § BrB. Skulle omfattninThis paper is, using a legal dogmatic method, analyzing established law regarding self-defence and excessive self-defence. The actual application of the laws in this field is not analyzed. The right of defence against violent criminal attacks is granted to the person being attacked, as well as anyone else nearby. This right is prescribed by 24 chapter 1 § Brottsbalken (the Swedish criminal code)
We studied the role of arachidonic acid metabolites, histamine, and 5-HT in airway responses to trimellitic anhydride (TMA) in actively sensitized guinea pigs. Sensitization was produced by two intradermal injections of free TMA (0.1 ml of 0.3% TMA in corn oil). After 21 to 28 days, guinea pigs were anesthetized and challenged with intratracheal instillation of 0.5% TMA conjugated to guinea pig se
The basement rocks of southern Sweden were deeply weathered in Late Triassic through Cretaceous times, and possibly even earlier. Sub-Mesozoic saprolites formed, presumably due to long-term warmth and humidity, in conjunction with decomposition of abundant organic matter and subsequent infiltration of acidic water. The upper parts of the weathering profiles were subjected to intense leaching and k
Bone morphogenetic protein-2 (BMP2) plays a key role in bone formation and maintenance. Studies of polymorphisms within the gene in relation to bone mineral density (BMD) and fracture have been inconsistent. Our aim was to investigate associations between polymorphisms in the BMP2 gene and bone mass, fracture, and quantitative ultrasound (QUS) measures at different stages of skeletal development.
Invasive species can displace natives, and thus identifying the traits that make aliens successful is crucial for predicting and preventing biodiversity loss. Pathogens may play an important role in the invasive process, facilitating colonization of their hosts in new continents and islands. According to the Novel Weapon Hypothesis, colonizers may out-compete local native species by bringing with
