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Graphene Oxide Network Formation and Crosslinking in Polybenzoxazines and Poly[(R)-3-hydroxybutyrate]

The search for improvement of the physical properties of two very dissimilar polymeric materials is the aim of this doctoral thesis. The high performance properties of polybenzoxazines are tackled via the preparation of novel amino-functional benzoxazine monomers, as well as by the addition of graphene oxide (GO) for the preparation of polybenzoxazine nanocomposites. The synthesis of the amino-fun

Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium

Rationale & Objective: Chronic kidney disease (CKD) is complicated by abnormalities that reflect disruption in filtration, tubular, and endocrine functions of the kidney. Our aim was to explore the relationship of specific laboratory result abnormalities and hypertension with the estimated glomerular filtration rate (eGFR) and albuminuria CKD staging framework. Study Design: Cross-sectional in

Maternal Long-Chain Polyunsaturated Fatty Acid Status, Methylmercury Exposure, and Birth Outcomes in a High-Fish-Eating Mother-Child Cohort

BACKGROUND: Maternal status of long-chain PUFAs (LC-PUFAs) may be related to fetal growth. Maternal fish consumption exposes the mother to the neurotoxicant methylmercury (MeHg), which, in contrast, may restrict fetal growth. OBJECTIVE: Our aim was to examine relations between maternal LC-PUFA status at 28 wk and birth outcomes (birth weight, length, and head circumference), controlling for MeHg e

Innovation Region Sweden

Älska Skog educational competition (Gothenburg, Sweden)Gothenburg-based educational institute Universeum is running annual design competitions on forest topics for primary school pupils, starting in 2016. Based on various activities in which pupils gain knowledge about forest-related challenges and opportunities as well as forestry, they would design plans to deal with those problems. After a firs

Surgeon heterogeneity significantly affects functional and oncological outcomes after radical prostatectomy in the Swedish LAPPRO trial

Objectives: To evaluate how surgeon heterogeneity – the variation in outcomes between individual surgeons – influences functional and oncological outcomes after robot-assisted laparoscopic prostatectomy (RALP) and retropubic radical prostatectomy (RRP), and to assess whether surgeon heterogeneity affects the comparison between RALP and RRP. Patients and Methods: Laparoscopic Prostatectomy Robot Op

Matched versus Haploidentical Hematopoietic Stem Cell Transplantation as Treatment Options for Primary Immunodeficiencies in Children : Matched and Haploidentical HSCT in PID

Primary immunodeficiencies (PIDs) are inherited disorders of the immune system with allogeneic hematopoietic stem cell transplantation (HSCT) as the only curative treatment in some of them. In case an HLA-matched donor is not available, HSCT from a haploidentical family donor may be considered. We compared the outcomes of HSCT from HLA-matched unrelated or related donors (MUDs or MRDs) and mismatc

Variability of BVOC Emissions from Commercially Used Willow (Salix spp.) Varieties

Willow (Salix spp.) trees are commonly used in short rotation coppices (SRC) to produce renewable energy. However, these plants are also known to emit high concentrations of biogenic volatile organic compounds (BVOCs), which have a large influence on air quality. Many different clones of commercially used Salix varieties exist today, but only a few studies have focused on BVOC emissions from these

Det könade patientskapet : Om det biopsykosociala perspektivets frånvaro när smärtpatienter möter allmänläkare

Approximately 20% of the population experience long-term pain. Women are generally more affected than men. Currently, pain researchers advocate a biopsychosocial perspective, which emphasises the importance of addressing psychological and social factors as well as biomedical ones in clinical practice. However, previous research shows that this holistic perspective is not always materialized in med

Afforestation driving long-term surface water browning

Increase in surface water color (browning), caused by rising dissolved organic carbon (DOC) and iron concentrations, has been widely reported and studied in the last couple of decades. This phenomenon has implications to aquatic ecosystem function and biogeochemical carbon cycling. While recovery from acidification and changes in climate-related variables, such as precipitation and length of growi

Molecular insight into carboxylic acid-alkali metal cations interactions : Reversed affinities and ion-pair formation revealed by non-linear optics and simulations

Specific interactions between the carboxylic acid moiety and the monovalent salts CsCl, NaCl, and LiCl, have been investigated in Langmuir monolayers using vibrational sum frequency spectroscopy (VSFS) and complemented with coarse grained and all-atom molecular dynamics simulations. By exploiting VSFS's intrinsic surface specificity, an emphasis was made on targeting headgroup vibrations of both i

The use of iohexol clearance to determine GFR in patients with severe chronic renal failure - a comparison between different clearance techniques

The nonionic low-osmolar contrast medium iohexol was used as marker of glomerular filtration rate (GFR) in 53 patients with stable renal function (group I: n = 32, group II: n = 21). All the patients had clearance values < or = 30 ml.min-1.1.73 m-2 body surface; 40 patients < 20 ml.min-1.1.73 m-2 body surface. Simultaneous determinations of renal clearance and plasma clearance, both as slope clear

Molecular recognition and dynamics in proteins studied by NMR

Knowledge of dynamics in protein is very important in the description of protein function and molecular recognition. The thesis investigates protein dynamics on time-scales from milli- to sub-nanosecond, with focus on the latter, using NMR spin relaxation experiments on two proteins, the 138-residue carbohydrate recognition domain of galectin-3 (Gal3C) and the 56-residue B1 domain of bacterial pro

Hardware Implementation of Baseband Processing for Massive MIMO

In the near future, the number of connected mobile devices and data-rates are expected to dramatically increase. Demands exceed the capability of the currently deployed (4G) wireless communication systems. Development of 5G systems is aiming for higher data-rates, better coverage, backward compatibility, and conforming with “green communication” to lower energy consumption. Massive Multiple-Input

BUS TRIPS—A self-management program for people with cognitive impairments after stroke

Stroke is a major cause of disability worldwide and different types of impairments can affect the individual’s ability to manage everyday activities such as travel that is essential for participation in society. The purpose of this study was to investigate the feasibility of a new self-management intervention (BUS TRIPS) focusing on travelling by bus, and potential contributions to an improved abi

Importance of the Geocoding Level for Historical Demographic Analyses : A Case Study of Rural Parishes in Sweden, 1850–1914

Geocoding longitudinal and individual-level historical demographic databases enables novel analyses of how micro-level geographic factors affected demographic outcomes over long periods. However, such detailed geocoding involves high costs. Additionally, the high spatial resolution cannot be properly utilized if inappropriate methods are used to quantify the geographic factors. We assess how diffe

Building and validating a prediction model for paediatric type 1 diabetes risk using next generation targeted sequencing of class II HLA genes

AIM: It is of interest to predict possible lifetime risk of type 1 diabetes (T1D) in young children for recruiting high-risk subjects into longitudinal studies of effective prevention strategies.METHODS: Utilizing a case-control study in Sweden, we applied a recently developed next generation targeted sequencing technology to genotype class II genes and applied an object-oriented regression to bui

The effect of continuous epidural infusion of ropivacaine (0.1%, 0.2% and 0.3%) on nerve conduction velocity and postural control in volunteers

BACKGROUND: Continuous epidural infusions of local anaesthetics have become increasingly popular in postoperative pain treatment, especially as they permit early mobilisation. Ropivacaine is a promising new agent which induces more pronounced sensory than motor blockade. This study was focused on the influence of continuous epidural infusion of ropivacaine on impulse conduction in large nerves (by

Mepolizumab for Eosinophilic Granulomatosis With Polyangiitis: A European Multicenter Observational Study

ObjectiveMepolizumab proved to be an efficacious treatment for eosinophilic granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the randomized, controlled MIRRA trial. In a few recently reported studies, successful real-life experiences with the approved dose for treating severe eosinophilic asthma (100 mg every 4 weeks) were observed. We undertook this study to assess the

Human-Robot Collaboration for Kinesthetic Teaching

Recent industrial interest in producing smaller volumes of products in shorter time frames, in contrast to mass production in previous decades, motivated the introduction of human–robot collaboration (HRC) in industrial settings, as an attempt to increase flexibility in manufacturing applications by incorporating human intelligence and dexterity to these processes. This thesis presents methods for