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A specific, highly enriching and "green" method for hollow fiber liquid phase microextraction of ionizable pharmaceuticals from fish tissue

Ionizable pharmaceuticals are a class of emerging contaminants that pose a challenge to analytical chemistry due to their low environmental concentrations. To measure such low concentrations in organism tissue, e.g. fish muscle, specific extraction techniques minimizing co-extraction and interference alongside providing high enrichment of the compounds are needed. In this study we present a techni

Xyloglucan endo-Transglycosylase-Mediated Xyloglucan Rearrangements in Developing Wood of Hybrid Aspen

Xyloglucan endo-transglycosylases (XETs) encoded by xyloglucan endo-transglycosylases/hydrolase (XTH) genes modify the xyloglucan-cellulose framework of plant cell walls, thereby regulating their expansion and strength. To evaluate the importance of XET in wood development, we studied xyloglucan dynamics and XTH gene expression in developing wood and modified XET activity in hybrid aspen (Populus

Plasma concentrations of Gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor sAxl in sepsis and systemic inflammatory response syndromes

Introduction: Gas6, the protein product of the growth arrest specific gene 6, is present in human circulation at subnanomolar concentrations. It is secreted by endothelial cells and is important for the activation of endothelium during inflammation. Axl, the tyrosine kinase receptor for Gas6, is also present in endothelium and can be cleaved and released into the circulation. The soluble of form A

Broad-scale latitudinal patterns of genetic diversity among native European and introduced house sparrow (Passer domesticus) populations.

Introduced species offer unique opportunities to study evolution in new environments, and some provide opportunities for understanding the mechanisms underlying macroecological patterns. We sought to determine how introduction history impacted genetic diversity and differentiation of the house sparrow (Passer domesticus), one of the most broadly distributed bird species. We screened eight microsat

Factors associated with lifetime risk of open-angle glaucoma blindness.

Purpose: To investigate factors associated with bilateral glaucoma blindness, particularly factors available at the time of diagnosis. Methods: Retrospective chart review of all patients with primary open-angle glaucoma (POAG) or pseudoexfoliative glaucoma (PEXG) followed at the Department of Ophthalmology or Low Vision Center of Skåne University Hospital, Malmö, Sweden, who died between January 2

Late-season mass-flowering red clover increases bumble bee queen and male densities

Spatiotemporal resource continuity promotes persistence of mobile animal populations. Current agricultural landscapes are poor in flowers resources for bumble bees. Available forage crops are predominantly early-season mass-flowering crops (MFC). It has been suggested, but not tested, that scarcity of late-season flower resources are limiting bumble bee populations. We examined whether addition of

Consistent individual differences in the social phenotypes of wild great tits, Parus major

Despite growing interest in animal social networks, surprisingly little is known about whether individuals are consistent in their social network characteristics. Networks are rarely repeatedly sampled; yet an assumption of individual consistency in social behaviour is often made when drawing conclusions about the consequences of social processes and structure. A characterization of such social ph

A novel interaction between the FLJ33534 locus and smoking in obesity: a genome-wide study of 14 131 Pakistani adults.

BackgroundObesity is a complex disease caused by the interplay of genetic and lifestyle factors, but identification of gene-lifestyle interactions in obesity has remained challenging. Few large-scale studies have reported use of genome-wide approaches to investigate gene-lifestyle interactions in obesity.MethodsIn the PROMIS study, a cross-sectional study based in Pakistan, we calculated BMI varia

Hospital-based home care for children with cancer: Feasibility and psychosocial impact on children and their families

Background To assess the feasibility and psychosocial impact of a hospital-based home care (HBHC) program for children with cancer. Procedure A HBHC program was carried out with 51 children (018 years) with cancer to assess its feasibility in terms of satisfaction, care preferences, safety, and cost. A controlled trial was conducted to assess children's health-related quality of life (HRQOL) using

Psychological differences between early and late onset psoriasis: A study of personality traits, anxiety and depression in psoriasis.

BACKGROUND: Onset of psoriasis may occur at any age. Early negative experiences often influence personality development, and may lead to physical disease, anxiety and depression in adulthood. Knowledge about onset of psoriasis and psychopathology is limited. OBJECTIVES: To examine whether patients with early onset psoriasis differ psychologically from patients with late onset, regarding personalit

The impact of ethnicity on glucose homeostasis after gestational diabetes mellitus.

The objective of this study was to examine measures of insulin resistance and beta cell function in relation to ethnicity and the development of diabetes after gestational diabetes mellitus (GDM). Glucose homeostasis was assessed during a 75 g oral glucose tolerance test 1-2 years after delivery in 456 women with previous GDM (362 European, 94 non-European; including 41 Arab and 43 Asian women) an

Context-dependent effects of yolk androgens on nestling growth and immune function in a multi-brooded passerine.

Female birds may adjust their offspring phenotype to the specific requirements of the environment by differential allocation of physiologically active substances into yolks, such as androgens. Yolk androgens have been shown to boost embryonic development, growth rate and competitive ability of nestlings, but they can also entail immunological costs. The balance between costs and benefits of androg

Land-use change in the Caucasus during and after the Nagorno-Karabakh conflict

Socioeconomic shocks can shape future land-use trajectories. Armed conflicts are an extreme form of a socioeconomic shock, but our understanding of how armed conflicts affect land-use change is limited. Our goal was to assess land-use changes related to the 1991–1994 Nagorno-Karabakh conflict between Armenia and Azerbaijan in the Caucasus region. We classified multi-temporal Landsat imagery, mappe

Green Colloid Chemistry: Characterization of Environmentally Friendly Nonionic Surfactant Systems

Popular Abstract in Swedish Tensider är amfifila molekyler, vilket innebär att de består av två delar. En av dessa är hydrofil (”vattenälskande”) och den andra är hydrofob (”vattenhatande”). Detta faktum ger tensider speciella egenskaper av vilken den viktigaste är att de självaggregerar i lösningsmedel (främst vatten), och bildar olika typer av aggregat, varav micellen är den mest kända. Dess spePhase diagrams of mixed alkylglucoside surfactants, n-nonyl-b-D-glucopyranoside and n-decyl-b-D-glucopyranoside (C9G1 and C10G1) have been examined for the purpose of determining the microstructure surrounding a closed-loop miscibiliyt gap. There are large deuterium isotope effects on the phase diagram. NMR-self diffusion, cryoTEM and TRFQ experiments show the presence of long interconnect network

Studies of the Effects of Industrial Processing on Fruit

Popular Abstract in Swedish Industriell produktion av bärkonserver innefattar flera enhetsoperationer, vilka alla påverkar sensoriska så väl som näringsmässiga kvaliteter hos produkten. Upptiningen är ett speciellt kritiskt steg eftersom förändringar i både kemisk sammansättning och textur sker. Upptining av jordgubbar i designade lösningar visade att bärens fasthet såväl som viktsförlusterna gickThe industrial production of preserves includes several unit operations which all affects sensorial properties as well as the nutritional value of the final product. Thawing is a crucial unit operation, since then both chemical and physical changes take place. Thawing strawberries in selected aqueous media could gave both firmer strawberries and smaller weight loss than if air was used as the tha

Experimental modulation and suppression of anti-allograft immune response

Abstract The objective of this investigation was to characterise the immunomodulatory or immunosuppressive effects of single drug treatment and the potential synergistic or additive effects of combined treatment with the focus on ciprofloxacin, thalidomide, mycophenolate mofetil, azathioprine, cyclophosphamide or leflunomide added to cyclosporin A (CyA). A rat cardiac transplant model was used to

Effekt av att använda kylväst under brandmansarbete

Syftet med denna undersökning var att bestämma en 1 kg isvästs kylverkan på kroppen vid brandmansarbete. Testerna genomfördes i en klimatkammare, i en container med extrem strålningsvärme och i ett rökdykningshus med värme och tungt arbete. Den faktiska kylverkan mättes också med en termisk docka. Fyra erfarna brandmän deltog i försöken. I alla tester bar försökspersonerna standardklädsel för branThe aim of the present study was to examine the effects of wearing a light-weight ice-vest (1kg, water) on physiological and subjective responses in fire fighter’s work. The experiments were carried out in a climatic chamber, in a container under extreme radiant heat, and during simulated smoke-diving. In addition, the physical cooling effect of the ice-vest was measured with a thermal mannequin.

A Metalloproteinase Karilysin Present in the Majority of Tannerella forsythia Isolates Inhibits All Pathways of the Complement System.

Tannerella forsythia is a poorly studied pathogen despite being one of the main causes of periodontitis, which is an inflammatory disease of the supporting structures of the teeth. We found that despite being recognized by all complement pathways, T. forsythia is resistant to killing by human complement, which is present at up to 70% of serum concentration in gingival crevicular fluid. Incubation

Comparison of 90-day case-fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis.

Yu K-H, Hong K-S, Lee B-C, Oh M-S, Cho Y-J, Koo J-S, Park J-M, Bae H-J, Han M-K, Ju Y-S, Kang D-W, Appelros P, Norrving B, Terent A. Comparison of 90-day case-fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis. Acta Neurol Scand: 2011: 123: 325-331. © 2010 John Wiley & Sons A/S. Background - It has not been clarified whether

Development and psychometric testing of the Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS).

Background: The aim of this study was to develop and psychometrically test a short, patient-reported questionnaire to be used in clinical practice for patients with Irritable Bowel Syndrome (IBS). The Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS) questionnaire was designed to measure the treatment response of symptoms and well-being in patients suffering from IBS. Methods: The VAS-I