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The research on perfluoroalkyl and polyfluoroalkyl substances (PFASs) in different research areas from the 1950s to the present.

Poly- och perfluorerade alkylsubstanser (PFAS) är en stor grupp av syntetiska miljöföroreningar som började att produceras i mitten av 1900-talet och har upptäckts globalt i miljön, människor och vilda djur. Oron över långtidseffekter ökar eftersom ämnena ansamlas i mänskliga organ och organismer samt att det fortfarande är osäkert hur dessa ämnen påverkar människor och djur. Djurförsök har visat Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are found globally in the environment, in humans and in wildlife and it is still not sure how these substances affect humans and animals. This study was performed as a systematic review to examine when these substances first attracted attention in different research areas. Also, to examine when the first publication was published and how the rese

Enzyme immobilization strategies for the synthesis of perdeuterated molecules

Användandet av nya strategier för immobilisering av enzymer (proteiner) möjliggör för stora framsteg inom neutron forskning. Genom noggranna tester upprättades väl valda villkor för användandet av enzymer, med ambitionen att effektivisera framställning av så kallade ”tunga molekyler”. Något som i sin tur är värdefullt för att förstå hur celler är strukturerade samt signalerar och interagerar med vThis thesis covers established procedures for the successful and attempted immobilization of lipases and phospholipases to various hydrophobic support materials, utilizing a rotating bed reactor, magnetic stirrer and tube-rotator. The design of a robust platform was established with great instrumental knowledge and proper conditioning for the creation of efficient immobilizations and activity assa

Initiativ för minskat matsvinn från livsmedelsbutiker

In Sweden there are several political goals stating the importance of diminished quantities of waste from the food sector, yet several thousand tons of potentially edible food are being discarded of every year. This study has examined the hindrances and opportunities of six different organizations/initiatives working to lower the rates of food waste from retail stores. It has also looked into pote

Flexibelt linjärservo med inverterad pendel

This master thesis is the first step in developing a new laboratory process for the automatic control basic course. The new process should illustrate the benefits of state-space control compared to PID control. A process with several outputs to control is then desired as a single PID controller does not support such a system. The suggested process consists of two carts mounted on a linear rail and

Samhällets kameleonter : En kvalitativ studie om andra generationens invandrares tredje identitet och mellanförskap

The overall aim of the study is to create a greater understanding of how individuals belonging to second-generation immigrants feel that their identity is shaped by living in different cultures at the same time. The purpose includes to understand these individuals' experiences of belonging and sense of identity. Furthermore, the purpose is to create a greater understanding of how their experie

Hur genomföring av ventilationskanaler påverkar lättregelväggars ljudisolering

När en ventilationskanal går igenom en ljudklassad vägg kommer reduktionstalet för skiljekonstruktionen att försämras då ljud kan överföras från det ena till det andra rummet via ventilationskanalen. För att förhindra en försämring av skiljekonstruktionens reduktionstal, vilket är syftet med den här studien, kan flertalet åtgärder tillämpas på kanalen. Tre ljudklassade väggar kombinerades med tre When a ventilation duct passes through a sound-classified wall, the sound reduction index for the combined wall will deteriorate as sound can be transmitted from one room to another via the ventilation duct. In order to prevent a deterioration of the sound reduction index, which is the purpose of the report, several measures can be applied to the duct. Three sound-classified walls are combined wit

A Matter of Privacy: How the substantial rule of law ensures fundamental rights in a digital era

I en alltmer digital värld överförs elektronisk information varje sekund till alla delar av världen. Denna elektroniska information övervakas av stater och dess offentliga myndigheter, vars övervakningsförmåga läcktes redan 2013 av Edward Snowden. På andra sidan av detta fenomen finns grundläggande rättigheter, nämligen rätten till integritet, skydd av personuppgifter, en opartisk domstol och till

Är transkvinnor riktiga kvinnor? En enkätstudie om svenskars transfobi

Syftet med den här digitala explicita enkätstudien är att undersöka vuxna svenskars attityder till transpersoner, eller deras nivå av transfobi. Teorierna som använts för att diskutera resultatet är social dominansteori (SDT), den heterosexuella matrisen och hegemonisk maskulinitet. Dessa teorier kan förklara den maskulina hierarkin som trumfar över femininitet, och som på grund av avvikande könsiThe aim of this digital explicit survey study is to examine adult Swedes’ attitudes towards transgender people, or their level of transphobia. The theories used to discuss the results of this study is social dominance theory (SDT), the heterosexual matrix and hegemonic masculinity. These theories could explain the masculine hierarchy that trump femininity, and due to gender nonconformity threatens

Tidningsdebatten i januari 2016 omkring de sexuella trakasserierna vid festivalen We are Sthlm

This essay will portray how articles in Swedish newspapers conveyed the sexual harassments that happened in a festival in Stockholm between 2014-2015 in the context of a media debate on sexual harassment, asylum seekers and police intervention that took place in January 2016. My research question is ”How have three Swedish newspapers dealt with the sexual harassments that took place at the We are

Dark-adapted spinach thylakoid protein heterogeneity offers insights into the photosystem II repair cycle

In higher plants, thylakoid membrane protein complexes show lateral heterogeneity in their distribution: photosystem (PS) II complexes are mostly located in grana stacks, whereas PSI and adenosine triphosphate (ATP) synthase are mostly found in the stroma-exposed thylakoids. However, recent research has revealed strong dynamics in distribution of photosystems and their light harvesting antenna alo

Coprolite morphotypes from the Upper Cretaceous of Sweden: novel views on an ancient ecosystem and implications for coprolite taphonomy

Coprolites (fossilized faeces) are common, yet previously unreported, elements in the Campanian (Upper Cretaceous) shallow-marine strata of Asen, southern Sweden. They are associated with a diverse vertebrate fauna and comprise at least seven different morphotypes that suggest a variety of source animals. Their faecal origin is corroborated by several lines of evidence, including chemical composit

Uptake of atrial fibrillation screening aiming at stroke prevention: geo-mapping of target population and non-participation

Background: In a screening study for silent atrial fibrillation (AF), which is a frequent source of cardiac emboli with ischemic stroke, the proportion of non-participants was considerable and their clinical profile differed from the participants' profile. We intended to geo-map the target population and non-participation in an attempt to understand factors related to screening uptake and, thereby

Reproductive toxicity of seafood contaminants: Prospective comparisons of Swedish east and west coast fishermen's families

Cohorts comprising fishermen's families on the east coast of Sweden have been found to have a high consumption of contaminated fish as well as high body burdens of persistent organochlorine pollutants (POPs). Their west coast correspondents are socio-economically similar, but with considerably lower POP exposure since the fish caught on the west coast is far less contaminated. The rationale for th

S100 protein in serum as a prognostic marker for cerebral injury in term newborn infants with hypoxic ischemic encephalopathy

The astroglial protein S100 is an established biochemical marker for CNS injury in the adult. The aim was to investigate whether S100 in serum is a prognostic marker of cerebral injury in term newborn infants, with hypoxic ischemic encephalopathy (HIE) after perinatal asphyxia. Serum S100 was measured on postnatal days 1-4 in 62 term infants with birth asphyxia. The infants were classified for HIE

Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives

Background & Aims: Iron overload may be carcinogenic. Patients with hereditary hemochromatosis (HH) are reportedly at a 20-200-fold risk of intrahepatic cancer, but the reported risks for nonhepatobiliary cancers are conflicting. The risk of cancer in heterozygous individuals (estimated allele frequency, 1/10 to 1/20) is unknown. This study aimed to better assess these risks. Methods: We perfo

Evaluation of Macular Structure and Function by OCT and Electrophysiology in Patients with Vitelliform Macular Dystrophy Due to Mutations in BEST1

PURPOSE. To analyze retinal structure and function in vitelliform macular dystrophy (VMD) due to mutations in BEST1. METHODS. Patients from five Swedish and four Danish families were examined with electrooculography (EOG), full-field electroretinography (ffERG), multifocal ERG (mfERG), optical coherence tomography (OCT), and fundus autofluorescence photography (FAF). Genetic analysis of the BEST1

Collagenous colitis. Epidemiology, risk factors, clinical presentation and associated autoimmune disorders

Popular Abstract in Swedish Diarré är ett vanligt symptom i befolkningen och det finns många differentialdiagnoser bakom orsaken till detta. En är inflammatorisk tarmsjukdom, något som har ökat kraftigt de senaste decennierna. Idag beräknar man att ca 1% av befolkningen har någon form av inflammatorisk tarmsjukdom och den klassas därför som en folksjukdom i Sverige. De inflammatoriska tarmsjukdomCollagenous colitis (CC) affects middle-aged women and results in chronic watery non-bloody diarrhoea. The incidence of CC has increased but has never been determined in southern Sweden. During the period 2001-2010 the mean annual incidence was stable; 5.4/105 (median age 71 years). The female: male ratio was 2.8:1, lower than in previous reports. The association between smoking and classic IBD is

Demokratins pris och litteraturens värde : böcker, politik och marknad i ljuset av 2002 års svenska bokmomssänkning

The Price of Democracy and the Value of Literature : Books, Politics, and the Literary Market with Respect to the 2002 Reduction in VAT on Books in Sweden In 2002 the VAT (value added tax) on books in Sweden was reduced from 25% to 6 %. The reduction was effected in response to a cultural policy, whose aim was to ”improve the conditions for literature and reading” and ”stimulate a diversifed out

Diffusion Tensor Tractography versus Volumetric Imaging in the Diagnosis of Behavioral Variant Frontotemporal Dementia.

MRI diffusion tensor imaging (DTI) studies of white matter integrity in behavioral variant frontotemporal dementia have consistently shown involvement of frontal and temporal white matter, corresponding to regional loss of cortical volume. Volumetric imaging has a suboptimal sensitivity as a diagnostic tool and thus we wanted to explore if DTI is a better method to discriminate patients and contro

Recurrent Non-Muscle-Invasive Bladder Cancer

A characteristic feature of non-muscle-invasive bladder cancer (NMIBC) is the high risk of recurrent disease after primary treatment. Although only a minority of cases eventually progress to a life-threatening muscle-invasive tumour, it is necessary to conduct long-term follow-up with repeated cystoscopies. In addition to the negative mental and physical impact that this has on the patient, the ex