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Standardization of p-creatinine assays and use of lean body mass allow improved prediction of calculated glomerular filtration rate in adults: A new equation

Objective. To evaluate the Cockcroft - Gault (CG) equation, using various body weight expressions, and the Sawyer equation in predicting glomerular filtration rate (GFR) using an enzymatic and zero-calibrated Jaffe plasma-creatinine assay, and to derive a new robust equation in adults. Material and methods. The CG weight measures included total, ideal and adjusted body weight (ABW; lowest of total

The Epistle of Jude : Its Text and Transmission

Popular Abstract in Swedish Avhandlingen behandlar det nytestamentliga Judasbrevets texthistoria. Monografin inleds med en översikt av textforskningen på de Katolska Breven i allmänhet och Judasbrevet i synnerhet, från 1800-talet och fram till nutid. Mot bakgrund av det tecknade forskningsläget beskriver så författaren studiens upplägg och syfte, samt antyder några av resultaten. Det handlar främsThis study treats the textual tradition of the Epistle of Jude. After an introductory survey of earlier text-critical research, the two main purposes of this investigation are formulated: to gather and to analyze the complete textual evidence of the Epistle of Jude. The first task, to gather the evidence, involves the collation of all Greek continuous text MSS of the Epistle of Jude. The evidence

Essays on Financial Markets

Popular Abstract in Swedish Denna avhandling innehåller fem essäer behandlande ett antal olika frågor inom området empirisk finansiell ekonomi. Genom användandet av kvantitativa metoder är syftet att studera praktiskt relevanta problem relaterade till hur finansiella marknader fungerar. Frågorna som tas upp sträcker sig från optionsprissättning och terminshedgning, över stokastisk volatilitets modThis thesis consists of five empirical essays dealing with different issues related to financial markets. Chapter 2 studies a new multivariate technique, Orthogonal GARCH, of forecasting large covariance matrices based on GARCH models. Orthogonal GARCH is built on principal component analysis and makes the creation of positive definite covariance matrices of arbitrary size possible. An important d

The Performance of a Multi Cylinder HCCI Engine using Variable Compression Ratio and Fast Thermal Management

Popular Abstract in Swedish Förbränningsmotor är i dagens värld den mest använda kraftkällan för fordon. Förbränningsmotorn har kontinuerligt utvecklats och förbättrats sedan Nicolaus August Ottos och Rudolf Diesels dagar, och kommer att fortsätta att utvecklas långt in i framtiden. Ingen konkurrerande teknik har ännu på allvar utmanat förbränningsmotorns ställning. Det finns en lång rad tänkbara The prime mover in the world today is the Internal Combustion (IC) engine. The development and improvement of the internal combustion engines since Nicolaus August Otto and Rudolf Diesel has continued until today and will continue long into the future. No major competitor to the IC engine has yet emerged. There is a long list of potential competitors but they still have to prove their superiority

Community guidelines to increase the reusability of marine microfossil assemblage data

Data on marine microfossil assemblage composition have multiple applications. Initially, they were primarily used for (chrono)stratigraphy and palaeoecology, but these data are now also widely used to study evolutionary and ecological processes, such as past biodiversity and its links with environmental dynamics, or to provide a basis for conservation efforts and biomonitoring. The large range of

Unsupervised Rural Flood Mapping from Bi-Temporal Sentinel-1 Images Using an Improved Wavelet-Fusion Flood-Change Index (IWFCI) and an Uncertainty-Sensitive Markov Random Field (USMRF) Model

Synthetic aperture radar (SAR) remote sensing (RS) technology is an ideal tool to map flooded areas on account of its all-time, all-weather imaging capability. Existing SAR data-based change detection approaches lack well-discriminant change indices for reliable floodwater mapping. To resolve this issue, an unsupervised change detection approach, made up of two main steps, is proposed for detectin

New Membrane process synergies for the food industry

Over the last two decades the market for membrane technology in the food industry increased to a market volume of approx. € 50 million and is now the second largest industrial market for membranes after municipal water treatment in Germany. The key membrane technologies in the food industry are the pressure driven membrane processes; microfiltration, ultrafiltration, nanofiltration and reverse osm

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

BACKGROUND: Factor VIII (FVIII) and its carrier protein von Willebrand factor (VWF) are associated with risk of arterial and venous thrombosis and with hemorrhagic disorders. We aimed to identify and functionally test novel genetic associations regulating plasma FVIII and VWF. METHODS: We meta-analyzed genome-wide association results from 46 354 individuals of European, African, East Asian, and Hi

Machine-learning and Discrimination: Procedural Challenges of Algorithmic Decision-making

The emergence of artificial intelligence, especially machine-learning methods, challenges the set of legal guarantees put in place in Europe to combat discrimination and ensure equal treatment. This paper will focus on cases of algorithmic discrimination in the context of recruitment as a business practice. Particular in the field of recruitment of workers, which has always been a field where EU n

Atrial fibrillation in immigrant groups : a cohort study of all adults 45 years of age and older in Sweden

To study the association between country of birth and incident atrial fibrillation (AF) in several immigrant groups in Sweden. The study population included all adults (n = 3,226,752) aged 45 years and older in Sweden. AF was defined as having at least one registered diagnosis of AF in the National Patient Register. The incidence of AF in different immigrant groups, using Swedish-born as referents

Efficacy of asenapine in manic episodes with depressive symptoms: A review of post-hoc analyses

Background: Manic episodes with depressive symptoms represent a severe presentation of bipolar disorder. The effi-cacy of drugs shown useful for pure mania is largely unproven in the subset of patients with depressive symptoms. We reviewed different post-hoc analyses evaluating asenapine's effects in patients experiencing depressive symptoms during manic episodes. Methods: Different post-hoc analy

An independent evaluation of a new method for automated interpretation of lung scintigrams using artificial neural networks

The purpose of this study was to evaluate a new automated method for the interpretation of lung perfusion scintigrams using patients from a hospital other than that where the method was developed, and then to compare the performance of the technique against that of experienced physicians. A total of 1,087 scintigrams from patients with suspected pulmonary embolism comprised the training group. The

Advancing 90-day mortality and anastomotic leakage predictions after oesophagectomy for cancer using Explainable Artificial Intelligence

Introduction: Oesophageal resection carries significant morbidity and mortality. Artificial intelligence (AI) advances in medical research enable enhanced predictions, flexibility, and interpretability, especially for complex interactions and nonlinear relationships. Material and methods: We used a register-based case-control design nested within prospectively collected data from the Swedish Natio

Metformin and incident osteoarthritis : Causal insights from a co-twin control study

Aims: In a co-twin control design, we aimed to examine whether individuals who initiate metformin treatment have an altered risk of incident diagnosis of osteoarthritis (OA), for up to 11 years after starting the treatment, compared with their non-treated co-twin. Methods: In all twin pairs different for metformin treatment (N=1 261 pairs) and all eligible twins/singletons (N=52 341) aged 35–75 ye

Utility Investment Planning using Risk Analysis: A Case Study of Tanzania’s Power Sector

Investments in infrastructure projects in developing countries are often seen as risky by private investors and local capital markets are not fully developed. Consequently, financial resources and guarantees are often to a large extent provided by financial institutions. Financial and economic analysis is important in assessing infrastructure investment proposals in order to assure that they are f

Impact of the COVID-19 pandemic on emergency and elective hip surgeries in Norway

Background and purpose — Many countries implemented strict lockdown policies to control the COVID-19 pandemic during March 2020. The impacts of lockdown policies on joint surgeries are unknown. Therefore, we assessed the effects of COVID-19 pandemic lockdown restrictions on the number of emergency and elective hip joint surgeries, and explored whether these procedures are more/less affected by loc

The relationship between O-chain expression and colonisation ability of Helicobacter pylori in a mouse model

The influence of lipopolysaccharide (LPS) O-polysaccharide chain production on the colonisation ability of Helicobacter pylori in four mouse models (NMRI, C57BL/6, CBA/Ca, and BALB/cA mice) was studied. H. pylori strains that produced smooth-form LPS (S-LPS) detectable in silver-stained electrophoretic gels colonised mice. In contrast, a laboratory-passaged strain G50 and the culture collection st

Wireless Esophageal pH Monitoring Is Better Tolerated than the Catheter-Based Technique: Results from a Randomized Cross-Over Trial.

OBJECTIVES: Esophageal pH monitoring using a wireless pH capsule has been suggested to generate less adverse symptoms resulting in improved patient acceptance compared with the catheter-based method although evidence to support this assumption is lacking. The aim of this study was to evaluate and compare the subjective experience of patients undergoing both techniques for esophageal pH monitoring.

Exploring patient perspectives : A qualitative inquiry into healthcare perceptions, experiences and satisfaction in Lebanon

BACKGROUND: Patient perspectives have received increasing importance within health systems over the past four decades. Measures of patient experience and satisfaction are commonly used. However, these measures do not capture all the information that is available through engaging with patients. An improved understanding of the various types of patient perspectives and the distinctions between them

I will help you, but will you help me? How the Perception of a Teachable Agent May Influence Performance

Learning by teaching someone else has proven to be beneficial in both human-human and human-agent interaction. Instructing someone else, that is, taking the role as a tutor, has a series of positive effects on students' learning and performance. For example, the fact that someone else is in need of help seems to affect students to put more effort into the task at hand, trying harder, being more th