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If we are being-of-the-world, how can we ever avoid participation? From this question Avhandling / Av_handling (Dissertation / Through_ action) unfolds. It invites to engage in an ongoing continuum of entanglements, where the moment of connection is unavoidable. This invitation demands that we are attentive to our mutual co-constitutiveness, that we take responsibility for what gets excluded as we
Background: Presence of circulating tumor cells (CTCs) is a validated prognostic marker in metastatic breast cancer. Additional prognostic information may be obtained by morphologic characterization of CTCs. We explored whether apoptotic CTCs, CTC clusters and leukocytes attached to CTCs are associated with breast cancer subtype and prognosis at base-line (BL) and in follow-up (FU) blood samples i
Background: The repertoire of measures of walking in Rett syndrome is limited. This study aimed to determine measurement properties of a modified two-minute walk test (2MWT) and a modified Rett syndrome-specific functional mobility scale (FMS-RS) in Rett syndrome. Methods: Forty-two girls and women with Rett syndrome (median 18.4 years, range 2.4–60.9 years) were assessed for clinical severity, gr
Popular Abstract in Swedish Populärvetenskaplig sammanfattning på svenska (Comprehensive summary in Swedish) Uppföljning av blodtryck (BT), medicinering och njurfunktion efter endovaskulär behandling av njurartärsteno's Bakgrund Förträngning av njuren's tillförande blodkärl, njurartärsteno's (RAS), är den vanligaste sekundära formen av högt BT (hypertension) och svarar för ca 1-5% av hypertensiRenal artery stenosis (RAS) causes hypertension, decreased glomerular filteration rate (GFR), and renal ischemia. RAS is progressive and causes 5-16% of all cases of renal failure. Prevalence of RAS in patients with hypertension is 1-5%. Today percutaneous transluminal renal angioplasty (PTRA) with or without stenting is a widely accepted treatment of RAS. Treatment of renal artery occlusion (RAO)
Purpose: Free prostate specific antigen (PSA) in serum consists of heterogeneous molecular subforms. Recently we developed an immunoassay for selective measurement of a subfraction of free PSA called intact PSA, which has been shown to be closely associated with prostate cancer. We assessed the ability of serum intact PSA to discriminate between benign and malignant prostatic disease. Materials an
Unsaturated solute transport is highly variable and therefore difficult to predict. In semi-arid areas, where water resources are limited, the presence of macropores is of great importance for crop production. The bromide ion (Br-) and dye tracers are useful for studies of water movement. One approach to describe the heterogeneous solute transport is to apply the concept of fractals to a dataset.
Popular Abstract in Swedish Det finns över 500 kräftarter i världen och vi hittar dem på alla kontinenter utom Antarktis och Arktis. I Sverige finns två arter, den inhemska flodkräftan och den introducerade signalkräftan. Signalkräftan introducerades till stor del för att ersätta förlusten av flodkräfta i många pestdrabbade vatten i södra Sverige. Att det just blev signalkräftan berodde främst på In this thesis I examine the dynamics of crayfish in streams and lakes. I have studied the influence of abiotic and biotic factors on abundance, growth, trophic position, niche breadth, and recruitment of crayfish, by conducting field studies, an outdoor channel experiment and timeseries analysis. Overall, the results show that abundance of crayfish is mostly affected by the abundance of predatory
Solar electricity is one of the most promising technologies for our future electricity supply. By using concentrators, it is possible to reduce the cost of generating photovoltaic electricity. This thesis discusses how to design stationary low concentrating systems for photovoltaic or PV/Thermal applications. The first chapters briefly explain the optics of solar energy concentrators. The theoreti
In 2014, more than 200,000 refugees and migrants fled for safety across the Mediterranean Sea. Crammed into overcrowded, unsafe boats, thousands drowned, prompting the Pope to warn that the sea was becoming a mass graveyard. The early months of 2015 saw no respite. In April alone more than 1,300 people drowned. This led to a large public outcry to increase rescue operations. Throughout this period
Popular Abstract in Swedish Muskelömhet hos kvinnor Smärttrösklar för tryck i skuldermuskulaturen (trapezius och deltoideus) i vila, efter muskel uttröttning och efter smärtsam stimulering Smärta i muskler och leder och besvär i form av upplevd trötthet i musklerna är vanligt förekommande problem, särskilt hos den kvinnliga delen av befolkningen. Man har ansett detta kopplat till olika belastandeLongstanding pain experienced from the musculoskeletal system is reported by one third of the Swedish population. The underlying mechanisms are not known in the majority of cases. In the present studies, the changes in pressure pain thresholds (PPTs) over the trapezius and deltoid muscles after a unilateral static contraction of maximal duration of one arm was measured in healthy females (n=25) a
Popular Abstract in Swedish Malaria är en allvarlig febersjukdom som varje år drabbar nästan 250 miljoner människor. Sjukdomen är mycket utbredd inom tropiska och subtropiska delar av världen och världshälsoorganisationen (WHO) har beräknat att strax under en miljon människor, majoriteten av dem barn, dör av malaria varje år. Malaria har följt människan under mycket lång tid och var länge vanlig iMalaria is a serious disease that causes around 800 000 deaths per year. Current malaria control efforts are hampered by the widespread resistance to common antimalarial drugs, such as the 4-aminoquinoline derivative called chloroquine. Previous research has shown that specific modifications of chloroquine, including inclusion of organometallic fragments into the organic framework, can result in c
Background: Lifestyle factors may influence the risk of developing pancreatic cancer. Whereas cigarette smoking is an established risk factor, the effects of high alcohol intake and obesity are more uncertain. The aim of the present study was to examine the associations of pre-diagnostic anthropometry, alcohol consumption, and smoking habits with pancreatic cancer risk in a Swedish prospective, po
Objective: To assess the quality of antibiotic prescribing in primary care in Belgium, the Netherlands and Sweden using European disease-specific antibiotic prescribing quality indicators (APQI) and taking into account the threshold to consult and national guidelines. Design: A retrospective observational database study. Setting: Routine primary health care registration networks in Belgium, the Ne
AbstractBackground Mitral regurgitation (MR) has many etiologies; the most common is degenerative disease. If not corrected, severe MR may cause left and right ventricular heart failure. Mitral valve (MV) repair is the gold standard for treatment of MR. All repair techniques include MV annuloplasty, but various techniques are employed to repair the valvular apparatus. The classical technique of le
Although prior falls are a well-established predictor of future fracture, there is currently limited evidence regarding the specific value of falls history in fracture risk assessment relative to that of other clinical risk factors and bone mineral density (BMD) measurement. We therefore investigated, across the three Osteoporotic Fractures in Men (MrOS) Study cohorts, whether past falls predicted
INTRODUCTION: More than 70 common alleles are known to be involved in breast cancer (BC) susceptibility, and several exhibit significant heterogeneity in their associations with different BC subtypes. Although there are differences in the association patterns between BRCA1 and BRCA2 mutation carriers and the general population for several loci, no study has comprehensively evaluated the associatio
BACKGROUND: Owing to the large variation in treatment response among patients with high-risk prostate cancer, it would be of value to use objective tools to monitor the status of bone metastases during clinical trials. Automated Bone Scan Index (aBSI) based on artificial intelligence has been proposed as an imaging biomarker for the quantification of skeletal metastases from bone scintigraphy.OBJE
This thesis is a contribution to the understanding of the life and work of Arnold Schoenberg as well as to musical hermeneutics. The aims are (1) to scrutinize Arnold Schoenberg’s marital crisis of the year 1908, (2) to probe into the meanings of some representative musical works during this very period, and (3) to compare features in Schoenberg’s life and his creative work. A number of documents
Popular Abstract in Swedish Spel och spelbräden har fått lite uppmärksamhet av forskare som undersöker de antika kulturerna. Denna avhandling samlar och analyserar arkeologiskt spelmaterial från bronsålderns Kreta, definierar forskningsfältet och presenterar ett ramverk med materialavgränsningar och typologier. Vidare undersöks spelandet som en del av socialhistorien. Varje del i avhandlingen - soThe old, world-wide phenomenon of playing board games has received little attention among scholars studying the ancient cultures. This thesis collects and analyses game-related material from Bronze Age Crete, defines the field of research and provides a framework with definitions and typologies. A further goal is to use the results of the analyses to extend beyond the archaeological material and e
The prognostic importance of tumor-specific nuclear insulin receptor (InsR) expression in breast cancer is unclear, while membrane and cytoplasmic localization of InsR is better characterized. The insulin signaling network is influenced by obesity and may interact with the estrogen receptor a (ERα) signaling. The purpose was to investigate the interplay between nuclear InsR, ER, body mass index (B
