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The impact of different evapotranspiration models in rainfall runoff modelling using HBV- light

The choice of which potential evapotranspiration (PET) model to use when estimating streamflow using a rainfall-runoff model have been the topic of many studies. The aim with this thesis was to assess the robustness of six different PET models using HBV-light as rainfall-runoff model over three catchments in Sweden. The robustness was evaluated by using a differential split sample test (DSST) base

Distanserade idéer En kvalitativ fallstudie om relationen mellan distansarbete och idégenerering i svenska startups.

Syftet med denna uppsats är att bidra till ökad kunskap kring relationen mellan distansarbete och idégenerering. Genom att belysa distansarbetets möjliga effekter på idégenerering i startups hoppas vi kunna bättre förstå hur arbete på distans påverkar idégenerering i innovativa organisationer. Studien är utformad som en kvalitativ fallstudie där den empiriska datan samlades in genom semistrukturerThe purpose of this study is to contribute to increased knowledge about the relationship between remote work and idea generation. By highlighting the possible effects of remote work in startups we hope to better understand how remote work has a relationship to idea generation in innovative organizations.The study is conducted as a qualitative case study. The empirical data has been gathered throug

A simulation-based framework for parametric energy renovation strategies in European buildings

This study presents a simulation-based framework for evaluating energy renovation strategies across European building typologies and climate zones. A factorial parametric approach was used to simulate over 800,000 combinations of envelope assemblies, HVAC systems, and shading controls for three archetypes (single-family, multi-family, office) across five European climate zones under both current a

The rs7903146 variant in the tcf7l2 gene increases the risk of prediabetes/type 2 diabetes in obese adolescents by impairing b-cell function and hepatic insulin sensitivity

OBJECTIVE In this study, we aimed to explore the mechanism by which TCF7L2 rs7903146 risk allele confers susceptibility to impaired glucose tolerance (IGT) or type 2 diabetes (T2D) in obese adolescents. RESEARCH DESIGN AND METHODS The rs7903146 variant in the TCF7L2 gene was genotyped in a multiethnic cohort of 955 youths. All subjects underwent an oral glucose tolerance test with the use of the O

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Titan, Demon and Genius in the Poetical Work of Mihai Eminescu is a book that furthers on the interpretation of the most representative Eminescu’s poems and also of his lyrical theatre. Besides, a special chapter is dedicated to the cultural context of the second half of the 19th century and another one records the literary works inspired by Eminescu’s works and personality throughout the 20th cen

An X-ray diffraction study of alterations in bovine lung surfactant bilayer structures induced by albumin.

Lung surfactant (LS) is an extra-cellular lipid-protein system responsible for maintaining low surface tension in the lung and alveolar stability. Serum proteins cause dysfunction of this material, e.g. in adult respiratory distress syndrome (ARDS). BLES is a clinically used LS consisting of most of the lipids and associated proteins from bovine lung lavage. Aqueous phases of BLES at 30% and 70% h

Coreceptor usage of sequential isolates from cynomolgus monkeys experimentally infected with simian immunodeficiency virus (SIVsm)

Sequential isolates from eight cynomolgus monkeys experimentally infected with Simian immunodeficiency virus (SIVsm, of sooty mangabey origin) were tested for coreceptor use in the human osteosarcoma indicator cell line, GHOST(3), expressing CD4 and one or another of the chemokine receptors CCR3, CCR5, CXCR4, BOB, or the orphan receptor Bonzo. The indicator cell line carries the human immunodefici

Effect of medical treatment in patients with systemic right ventricle

Objective: Congenitally corrected and surgical atrial redirected transposition of the great arteries (TGA) represents states where the morphological right ventricle serves as a systemic ventricle (S-RV). The S-RV is prone to failure, but data on medical treatment on this problem is limited. The purpose of this study was to evaluate the survival in adults with S-RV, with or without heart failure tr

A prospective study on effectiveness of elevated intraocular pressure as a criterion for glaucoma referrals by optometric practitioners in Sweden

Purpose: To evaluate the outcome of referrals for suspected glaucoma based on elevated intraocular pressure (IOP) made by optometric practitioners in Sweden. Methods: This prospective study included 95 individuals referred to the Skåne University Hospital Malmö, Sweden, during 2019, by optometric practitioners, based on elevated IOP. Positive outcome was defined as a diagnosis of glaucoma, or a di

Multi-steps green process for synthesis of six-membered functional cyclic carbonate from trimethylolpropane by lipase catalyzed methacrylation and carbonation, and thermal cyclization.

A highly functionalized six-membered cyclic carbonate, methacrylated trimethylolpropane (TMP) cyclic carbonate, which can be used as a potential monomer for bisphenol-free polycarbonates and isocyanate-free polyurethanes, was synthesized by two steps transesterifications catalyzed by immobilized Candida antarctica lipase B, Novozym®435 (N435) followed by thermal cyclization. TMP was functionalized

Release of a Poorly Soluble Drug from Hydrophobically Modified Poly (Acrylic Acid) in Simulated Intestinal Fluids.

A large part of new pharmaceutical substances are characterized by a poor solubility and high hydrophobicity, which might lead to a difference in drug adsorption between fasted and fed patients. We have previously evaluated the release of hydrophobic drugs from tablets based on Pemulen TR2 and showed that the release can be manipulated by adding surfactants. Here we further evaluate the possibilit

Reconstructing the formation of a costal aquifer in Nampula province, Mozambique, from ERT and IP methods for water prospection

In continental margin basins, the hydrogeological setting is complex due to transgression/regression events that removed old sediments in the basin and formed new geologic units. Due to the geological complexity, the use of vertical electrical sounding has proven to be insufficient for groundwater explorations. The lack of understanding the geological underground has resulted in many boreholes wit

The relative contribution of hemodynamic parameters to blood pressure decrease in classical orthostatic hypotension

PURPOSE: We studied the relative contributions of total peripheral resistance (TPR), stroke volume (SV) and heart rate (HR) to low blood pressure in classical orthostatic hypotension (cOH) on group and individual levels.METHODS: We retrospectively analyzed tilt test records from cOH patients and age/sex-matched controls. We quantified relative effects of HR, SV and TPR on mean arterial pressure (M

Brexit references in UK financial disclosure discourse (2015-2017) : a corpus study

Major political events become a dominant topic of the discussions in the countries involved, and various actors, often other than political parties, take a stance towards them. The withdrawal of the UK from the European Union as a result of the 2016 UK referendum was one of those, and a quite polarised atmosphere from supporters of both sides was observed in the UK and the rest of Europe since the

Nocturnal passerine migrants fly faster in spring than in autumn: a test of the time minimization hypothesis

It has been suggested that time selection and precedence in arrival order are more important during spring than autumn migration. Migrating birds are expected to fly at faster airspeeds if they minimize duration rather than energy costs of migration, and they are furthermore expected to complete their journeys by final sprint flights if it is particularly important to arrive at the destination bef

Suppression of NDA-type alternative mitochondrial NAD(P)H dehydrogenases in Arabidopsis thaliana modifies growth and metabolism, but not high light stimulation of mitochondrial electron transport.

The plant respiratory chain contains several pathways which bypass the energy-conserving electron transport complexes I, III, and IV. These energy-bypasses, including type II NAD(P)H dehydrogenases and the alternative oxidase (AOX), may have a role in redox-stabilisation and regulation, but current evidence is inconclusive. Using RNA interference, we generated Arabidopsis thaliana plants simultane

A coarse-grained model for flexible (phospho)proteins: Adsorption and bulk properties

Protein adsorption is a complex process that it controlled by several different mechanisms, for example: (i) electrostatic interactions between the protein and the surface, and (ii) between adsorbed proteins; (iii) dispersion interactions; (iv) hydration effects; and (v) structural rearrangements of the protein to balance conformational chain entropy with energetics. The aim of this study was to d

Radiocarbon and hydrocarbon analysis of pm sources during whtc tests on a biodiesel-fueled engine

PM in diesel exhaust has been given much attention due to its adverse effect on both climate and health. As the PM emission levels are tightened, the portion of particles originating from the lubrication oil is likely to increase. In this study, exhausts from a biodiesel-fueled Euro 5 engine were examined to determine how much of the carbonaceous particles that originated from the fuel and the lub

Intergenerational effects of dietary changes on trait means and variance

Environmental stress can alter not only trait means but also trait variances - an often-overlooked evolvable feature with ecological and evolutionary relevance. We examine how dietary stress affects both the mean and variance of morphological and reproductive traits across two generations in clonal Daphnia. We manipulated maternal and offspring environments with high- (algae) or low-quality (cyano