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MOCCA code for star cluster simulations - IV. A new scenario for intermediate mass black hole formation in globular clusters

We discuss a new scenario for the formation of intermediate mass black holes (IMBHs) in dense star clusters. In this scenario, IMBHs are formed as a result of dynamical interactions of hard binaries containing a stellar-mass black hole (BH), with other stars and binaries. We discuss the necessary conditions to initiate the process of intermediate mass BH formation and the influence of an IMBH on t

Volatile organic compound emission in tundra shrubs : Dependence on species characteristics and the near-surface environment

Temperature is one of the key abiotic factors during the life of plants, especially in the Arctic region which is currently experiencing rapid climate change. We evaluated plant traits and environmental variables determining leaf temperature in tundra shrubs and volatile organic compound (VOC) emissions with field measurements on deciduous tundra shrubs, Salix myrsinites and Betula nana, and everg

Clinical validity of increased cortical binding of tau ligands of the THK family and PBB3 on PET as biomarkers for Alzheimer’s disease in the context of a structured 5-phase development framework

Purpose: The research community has focused on defining reliable biomarkers for the early detection of the pathological hallmarks of Alzheimer’s disease (AD). In 2017, the Geneva AD Biomarker Roadmap initiative adapted the framework for the systematic validation of oncological biomarkers to AD, with the aim to accelerate their development and implementation in clinical practice. The aim of this wo

Ultraviolet filters in stomatopod crustaceans : diversity, ecology and evolution

Stomatopod crustaceans employ unique ultraviolet (UV) optical filters in order to tune the spectral sensitivities of their UV-sensitive photoreceptors. In the stomatopod species Neogonodactylus oerstedii, we previously found four filter types, produced by five distinct mycosporine-like amino acid pigments in the crystalline cones of their specialized midband ommatidial facets. This UV-spectral tun

Fine root classification matters : nutrient levels in different functional categories, orders and diameters of roots in boreal Pinus sylvestris across a latitudinal gradient

Background: Fine roots and their symbionts are the key drivers of processes such as nutrient cycling and belowground productivity. Their function depends on position in a branching hierarchy, with absorptive roots (responsible for resource acquisition), and transport roots. Aim: We examined how the different diameter cutoffs for root classification mirror concentrations of 11 different nutrients,

Physical activity and survival following breast cancer

INTRODUCTION:Physical activity (PA) leads to improved survival in women following the diagnosis of breast cancer, but it is less clear whether PA has equally positive effects regardless of age at diagnosis. The purpose of our study was to evaluate the association between post-diagnosis PA and survival in women aged below or over 55 years at diagnosis.METHODS:From a prospective population-based coh

Modelling Populus autumn phenology : The importance of temperature and photoperiod

In late summer-early autumn, trees undergo growth cessation culminating in bud set. For a wide range of plants, including Populus, photoperiod is considered as the primary environmental cue determining timing of growth cessation and shoot to bud transition. However, studies on Populus have revealed temperature influence on seasonal growth cessation and bud set. In this study we examine the role of

House dust mite impairs antiviral response in asthma exacerbation models through its effects on TLR3

BACKGROUND: Impaired antiviral interferon expression may be involved in asthma exacerbations commonly caused by rhinovirus infections. Allergy is a known risk factor for viral-induced asthma exacerbation, but little is known whether allergens may affect interferon responses.OBJECTIVE: Our hypothesis is that house dust mite (HDM) impairs viral stimulus-induced antiviral signalling.METHODS: Experime

Pupil size and search performance in low and high perceptual load

The ability to focus on a task while disregarding irrelevant information is an example of selective attention. The perceptual-load hypothesis argues that the occurrence of early or late selection mechanisms is determined by task-relevant perceptual load. Additionally, evidence shows that pupil size serves as proxy of locus coeruleus-norepinephrine (LC-NE) activity, a system associated with cogniti

Volcanic impact on the climate - The stratospheric aerosol load in the period 2006-2015

We present a study on the stratospheric aerosol load during 2006-2015, discuss the influence from volcanism and other sources, and reconstruct an aerosol optical depth (AOD) data set in a resolution of 1° latitudinally and 8 days timewise. The purpose is to include the "entire" stratosphere, from the tropopause to the almost particle-free altitudes of the midstratosphere. A dynamic tropopause of 1

On the interaction between single chain Fv antibodies and bacterial immunoglobulin-binding proteins

Using four bacterial immunoglobulin-binding proteins, we have analyzed the binding characteristics of a panel of 34 human single chain Fv antibodies, expressed in E. coli and with known specificity and sequence. Several of the single chain Fv antibodies showed affinity for staphylococcal protein A and peptostreptococcal protein L, but not for the streptococcal proteins G or H. The affinity of the

Incidence of referred carpal tunnel syndrome and carpal tunnel release surgery in the general population : Increase over time and regional variations

Purpose: To investigate the change in incidence of referred carpal tunnel syndrome (CTS) and carpal tunnel release (CTR) surgery over time and regional variations. Methods: From the nationwide patient registry, we identified all adult individuals who had received first-time CTS diagnosis (International Classification of Diseases, 10th Revision code G560) at secondary or tertiary level and first-ti

Modeled aerosol-cloud indirect effects and processes based on an observed partially glaciated marine deep convective cloud case

A tropical maritime case of deep convective clouds was studied using a state-of-the-art aerosol-cloud model in order to evaluate the microphysical mechanisms of aerosol indirect effects (AIE). The aerosol-cloud scheme used is a hybrid bin/bulk model, which treats all phases of clouds and precipitation allowing a detailed analysis of process-level aerosol indirect effects on targeted cloud types.

Strategic decisions : behavioral differences between CEOs and others

We study whether CEOs of private firms differ from other people with regard to their strategic decisions and beliefs about others’ strategy choices. Such differences are interesting since CEOs make decisions that are economically more relevant, because they affect not only their own utility or the well-being of household members, but the utility of many stakeholders inside and outside of the organ

Functional connectivity changes in core resting state networks are associated with cognitive performance in systemic lupus erythematosus

To investigate core resting state networks in SLE patients with and without neuropsychiatric symptoms by examining functional connectivity changes correlating with results of cognitive testing. Structural MRI and resting state-fMRI (rs-fMRI) were performed in 61 female SLE patients (mean age: 36.8 years, range 18.2–52.0 years) and 20 healthy controls (HC) (mean age 36.2 years, range 23.3–52.2 year

The mortality increase in cardiac surgery patients associated with shrunken pore syndrome correlates with the eGFR cystatin C /eGFR creatinine -ratio

Shrunken pore syndrome (SPS) is a condition in which estimated glomerular filtration rate (eGFR) based upon cystatin C is lower than eGFR based upon creatinine. It has been associated with increased mortality even in the presence of normal GFR in both a cardiac surgical population and a general population. No systematic studies of the variation in eGFR cystatin C /eGFR creatinine -ratio used fo

Persistent and context-dependent effects of the larval feeding environment on post-metamorphic performance through the adult stage

One of the central issues in ecology is the identification of processes affecting the population structure and dynamics of species with complex life cycles. In such species, variation in both the number of larvae that enter a population and their phenotype are important drivers of survival and growth after metamorphosis. Larval experience can have strong effects on key postmetamorphic traits, but

Questionnaire-based evaluation of sexual life after laparoscopic surgery for endometriosis : A systematic review of prospective studies

Introduction: Endometriosis is a benign disease that affects women of reproductive age. Laparoscopic excision of endometriotic implants is considered one of the most effective therapeutic options. The disease and its treatment can have a major impact on psychosexual well-being but this is often overlooked as most studies focus on pain instead of sexuality in a holistic approach. The aim of this st

The evolution and convergence of total quality management and management theories

This study compares the historical evolution of Total Quality Management (TQM) to eight well-known management theories to investigate whether there are affinities between TQM and the selected management theories. The study uses the core values and components of the EFQM Excellence Model as the framework for the analysis which reveals that most of the ingredients in the selected management theories