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INTRODUCTION: Hip and knee osteoarthritis is a leading cause of disability worldwide. Currently, the course of deterioration in pain and physical functioning in individuals with osteoarthritis is difficult to predict. Factors such as socioeconomic status and comorbidity contribute to progression of osteoarthritis, but clear associations have not been established. There is a need for early identifi

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Development of multiple colorectal cancers (CRCs), synchronously or metachronously, is associated with hereditary predisposition for cancer and accurate risk estimates of multiple tumour development are relevant to recommend rational surveillance programs. A cross-sectional study design was used to estimate the risks of synchronous CRC (SCRC) and metachronous CRC (MCRC) based on data from the Nati

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Ultrafiltration can be used to concentrate arabinoxylan isolated from wheat bran. Prefiltration with diatomaceous earth and air sparging during ultrafiltration of the alkaline hemicellulose solution were both found to increase the flux, while nitrogen sparging had no effect. The flux of the untreated solution was 51 L/m2 h, while the flux after prefiltration of the solution with diatomaceous earth

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Basement membranes (BMs) are specialized layers of extracellular matrix (ECM) mainly composed of Laminin, type IV Collagen, Perlecan and Nidogen/entactin (NDG). Recent in vivo studies challenged the initially proposed role of NDG as a major ECM linker molecule by revealing dispensability for viability and BM formation. Here, we report the characterization of the single Ndg gene in Drosophila. Embr

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Galectin-3 is a carbohydrate binding protein which has important roles in cancer and immunity. Potent galectin-3 inhibitors have been synthesized, for experimental purposes and potential clinical use. As galectin-3 is implicated in both intra- and extracellular activities, permeability of galectin-3 inhibitors is an important parameter determining biological effects. We compared the cellular uptak

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IntroductionThe World Health Organization (WHO) has concluded that physical inactivity and overweight/obesity are the world's fourth and fifth leading risk factors for non-communicable diseases, respectively. This article investigates the potential for active commuting by bicycle in Scania county, southern Sweden, and its possible impact on public health. Physical inactivity is a growing problem o

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This thesis consists of four self-contained papers in applied microeconomics. The first paper asks how a neighbors purchase of a specific good affects a households likelihood of purchase. I use an image classification algorithm to process a large set of aerial photos in order to infer household ownership of a visible durable good, specifically a trampoline. To estimate the neighborhood effect, I u

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The subjects of this article are Kozhevnikov and Chistovitch's finding regarding the constancy of relative syllable durations and the inconstancy of relative speech sound durations for different rates of speech, and their proposal that vowels are elided because the necessary minimum duration of a consonant consumes all the time that happens to have been assigned to the syllable. The relative cons

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Up until the late nineteenth and early twentieth century, and probably since the introduction of agriculture to Sweden, the social life, culture, traditions, building patterns and material culture would largely have been based on agricultural practices. And yet, in the archaeological record, agricultural aspects of social life remain elusive and little is known about the organization of farming an

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Future anthropogenic climate change is likely to increase the air temperature (T a ) across Europe and increase the frequency, duration and magnitude of severe heat stress events. Heat stress events are generally associated with clear-sky conditions and high T a , which give rise to high radiant heat load, i.e. mean radiant temperature (T mrt ). In urban environments, T mrt is strongly influenced

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The successful planning, design and management of a traffic system is impossible without knowledge of how the traffic environment affects the behaviour of road users and how the behaviour is related to the main qualities of the traffic system (e.g. safety, efficiency). Automated video analysis is a promising tool for traffic behaviour research in that it enables collection of micro-level behaviour

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Benchmarking is an effective tool to compare the performance of full-scale wastewater treatment plant operation. In this study, 29 wastewater treatment plants from eight countries were surveyed with the aim of developing some key performance indicators, which may be used for benchmarking purposes. The level of utilisation of instrumentation, control and automation (ICA) has also been measured. The

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This study was aimed to optimize glucose level at different stages of buffalo in vitro embryo production procedure. Three glucose levels (1.5, 5.6 and 10 mm) along with a control (0 mm) were used at three phases of in vitro fertilisation (IVF) procedure viz. in vitro maturation (IVM), in vitro culture (IVC-I) (12-72 hpi) and IVC-II (72 hpi to 7 dpi). Maturation rate of oocytes was found different

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The mutation status of the immunoglobulin heavy chain variable regions (IgVH) has been found to be a good prognostic indicator for B-cell chronic lymphocytic leukemia (CLL) because unmutated VH genes are associated with rapid disease progression and shorter survival time. To study the differences in gene expression between the Ig-unmutated and Ig-mutated CLL subtypes, we performed gene expression

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Atmospheric ions participate in the formation of new atmospheric aerosol particles, yet their exact role in this process has remained unclear. Here we derive a new simple parameterization for ion-induced nucleation or, more precisely, for the formation rate of charged 2-nm particles. The parameterization is semi-empirical in the sense that it is based on comprehensive results of one-year-long atmo

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Background: Contact hypersensitivity quantitative risk assessment (QRA) for fragrance ingredients is being used to establish new international standards for all fragrance ingredients that are potential skin sensitizers. Objective: The objective was to evaluate the retrospective clinical data on three fragrance ingredients in order to provide a practical assessment of the predictive value of the QR

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Ethanolic fermentation of lignocellulose raw materials requires industrial xylose-fermenting strains capable of complete and efficient D-xylose consumption. A central question in xylose fermentation by Saccharomyces cerevisiae engineered for xylose fermentation is to improve the xylose uptake. In the current study, the glucose/xylose facilitator Gxf1 from Candida intermedia, was expressed in three

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A new glacial geomorphological map of the Eyjabakkajokull forefield in Iceland is presented. The map covers c. 60 km(2) and is based on high-resolution aerial photographs recorded in August 2008 as well as field checking. Landforms are manually registered in a geographical information system (ArcGIS) based on inspection of orthorectified imagery and digital elevation models of the area. We mapped

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The polymorphism in the copper(II) alkanoates, recently discovered for one member, has been thoroughly studied for the whole series, from 3 to 16 C atoms. Three polymorphic phases have been found, all of them sharing the same molecular unit, the paddle-wheel, which grows forming a 1D coordination polymer or catena. The three polymorphs are defined by a different packing of these catenae and a spec

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Objective: Negative pressure wound therapy (NPWT) is a recently introduced treatment modality for post-sternotomy mediastinitis. The aim of this study was to compare the mortality rate, the sternal re-infection rate and the length of hospital stay in patients with post-sternotomy mediastinitis after NPWT and conventional treatment. Methods: We retrospectively analysed 118 patients with post-sterno