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This work deals with a detailed analysis of the vibrational spectra of methoxy (CH3O-) and ethoxy (CH3CH2O-) on W(110) and Cu(100) single crystal surfaces. By using theoretical ab initio quantum mechanical modeling, it is demonstrated that an unprecedented quantitative understanding of the vibrational frequencies of a surface adsorbate can be obtained. A qua
The secondary structure of proteins is crucial for proper function of the protein in biological systems. Peptide T, an octapeptide from the envelope glycoprotein gp120 of the HIV virus, has previously been shown to be responsible for binding to the CD4 receptor on T helper/inducer lymphocytes. NMR studies showed that the four C-terminal amino acid residues of peptide T adopted a beta-turn conforma
Popular Abstract in Swedish Bröstcancer är den vanligast förekommande cancerformen hos kvinnor. Under sin livstid kommer tio procent av den kvinnliga befolkningen att få bröstcancer men endast en minoritet kommer att avlida av den. Operation är den vanligaste behandlingen och kombineras oftast med strålbehandling. Armlymfödem samt nedsatt axelrörlighet och muskelstyrka är välkända sidoeffekter tilTen percent of the female population in Sweden will be diagnosed with breast cancer during their lifetime, but only a minority will die from the disease. Arm lymph oedema is a well-known complication following breast cancer treatment and the incidence varies between about 10% when axillary node dissection is performed and about 40% when axillary radiotherapy is added. The general aim of this thes
Aims To investigate the causal role of high-density lipoprotein cholesterol (HDL-C) and triglycerides in coronary heart disease (CHD) using multiple instrumental variables for Mendelian randomization. Methods and results We developed weighted allele scores based on single nucleotide polymorphisms (SNPs) with established associations with HDL-C, triglycerides, and low-density lipoprotein cholestero
The overall aim of this research was to investigate the safety of oral care in terms of intracranial dynamics and changes in oral health during intubation and 48 hours after extubation among neuroscience intensive care unit (NICU) patients. Additional aims included comparison of a comprehensive oral care protocol (i.e., tongue scraping, electric toothbrush, non-foaming toothpaste, and application
Popular Abstract in Swedish Summary in Swedish Populärvetenskaplig sammanfattning Förhöjt blodtryck, s.k. hypertension, är en folksjukdom i västvärlden och en riskfaktor för hjärtkärlsjukdomar som hjärtinfarkt och stroke (slaganfall). Ca 27 % av den vuxna befolkningen i Sverige beräknas ha hypertension och är lika fördelad mellan män och kvinnor. Salt beräknas bidra till förhöjt blodtryck och kan Abstract The average amount of salt ingested is about 10 grams daily compared to less than one gram in pre-historic life. Salt, althought somewhat debated, is considered a risk factor for elevated blood pressure and end organ damage beyond the blood pressure effect. Thus, salt contributes to the hypertensive phenotype, increase risk of cardiovasvcular disease, deaths and is a great socioeconomic
Popular Abstract in Swedish Sedan 1981, då de första fallen av AIDS beskrevs, har 25 miljoner människor dött på grund av att de har blivit smittade av immunbristviruset HIV . Det finns idag mer än 40 miljoner människor som lever med HIV eller AIDS. SIV är apsläktets variant på HIV och orsakar normalt ingen sjukdom hos sina värddjur som är olika afrikanska apor, men då asiatiska apor, t. ex. makakeSimian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. SIV use CCR5 and rarely CXCR4 but may use other coreceptors as alternatives. We have studied vi
Popular Abstract in Swedish Föreliggande avhandling är en fallstudie vars empiriska material utgörs av kvalitativa forskningsintervjuer, deltagande observationer och textdokument. Avhandlingen uppmärksammar ett händelseförlopp på en nystartad svensk gymnasieskola. Förloppet inleds med kommunens och rektorns stora visioner för verksamheten och avslutas med att en samstämmig lärargrupp avsätter rektThis dissertation is based on a case study of a series of events at a newly started Swedish high school. The study employs a qualitative methodology comprising of interviews, participant observation and analysis of text documents. The series of events opens with the grand visions of the municipality and the school's principal for the school and concludes with the teachers at the school unanimously
This thesis concerns nozzles and their impact on droplet formation and droplet flight in a continuous ink jet printer. Methods are suggested to characterise droplet formation and droplet flight stability (D.F.S.). A study about the influence of droplet flight stability on the quality of print out is presented. A method to assess the charging process for the continuous ink jet is described. The dev
Popular Abstract in Swedish ETT PARADIS FÖR ALLA. EPA MELLAN FOLKHEM OCH FÖRFÖRELSE I början av 1930-talet etablerades en ny form av konsumtion i Sverige när Enhetsprisaktibolaget Epa öppnade dörrarna för en hänförd och överväldigad allmänhet. Hörnstenar i Epa-systemet var fasta priser, massproducerade produkter, stora lagerutrymmen och låga leveranskostnader. Varorna var avsedda för en ny bred kA Paradise for All. Epa between the People's Home and Seduction. This dissertation is about the Epa department store chain, which existed in Sweden from 1930 to 1977. For many people, Epa was an arena for meeting modernity. By allowing issues of tradition and modernity, cultural learning processes, class, gender and aesthetics to collide with the Epa phenomenon, a complex picture of the Swedish P
Background. Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish intake may be associated with a decreased risk, but the existing evidence is less convincing. Methods: We prospectively followed 478040 men and women from 10 European countries who were free of cancer at enrollment between 1992 and 1998. Information on diet and lifestyle w
1 We examined non-adrenergic, non-cholinergic (NANC) stimulation for its stabilizing effect on bronchial smooth-muscle tone with respect to its regulatory power and the effect of variations in neural impulse frequency. 2 The guinea-pig isolated main bronchus (n = 4-12) was pretreated with indomethacin (1O JAM) and incubated with atropine (1 pM) and guanethidine (10 JM). Electrical field stimulatio
Popular Abstract in Swedish Spel om pengar har blivit ett utbrett fenomen i Sverige under 1990-talet, med spelbutiker, spelhörnor i varuhusen, spelmaskiner och spel med kort och på roulette på pubar, pizzerior och restauranger, samt spel på Bingo-Lotto hemma i vardagsrummet. Förutom den ökade tillgången till legala spelformer blir det allt vanligare med spel i miljöer och sammanhang där det inte fGambling has become widely accepted in Sweden during the 1990s, with betting shops, gambling machines and casino-like gambling in pubs and restaurants, as well as Bingo-Lotto in our living rooms. Beyond the expansion in availability of legal gambling opportunities, the most notable change is the shift from gambling in specific venues to gambling in a much wider range of social settings. The conseq
Introduction. Along with the great expansion of research being published in Open Access (OA) journals over the last decade, the interest for analysing the OA literature using informetric methods has also increased. Most studies have focused on the citation impact of OA journals and whether OA publishing increases the chances of a research publication being cited. Fewer analyses, however, have inve
Popular Abstract in Swedish Alla levande organismer har DNA, och eftersom DNA är livsnödvändigt måste det repareras om det blir skadat. Ultraviolett (UV) strålning från solen är en av de vanligaste orsakerna till att DNA skadas. De flesta skador på DNA som orsakas av UV-strålning utgörs av cyklobutan-pyrimidindimerer (CPD) eller (6-4)-fotoprodukter. Dessa skador består av två intilliggande baser sAll living organisms have DNA and since DNA is essential to life it must be repaired when damaged. UV radiation is one of the major DNA damaging agents, which photosynthetic organisms cannot avoid. The major UV-induced DNA lesions are cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts (6-4PPs) and the main repair pathways of theses lesions involve photolyases and various excision repair
Gas phase reactions at elevated temperatures are versatile tools for material manufacturing and energy conversion. They are of great commercial interest, but they often entail hazardous impacts on the environment. There is consequently a pronounced need for the further develpment of processes utilising these types of reactions. Spectroscopic methods, especially when combined with lasers, are idea
This dissertation has three cornerstones: * Haptics * Human-Computer Interaction (HCI) * Blind Users Haptics deals with controlling human movements and getting feedback through the sense of touch. A haptic interface transmits forces to a person’s hand or fingers in a way that mimics the sensation of touching real objects. Virtual haptic touch can be particularly useful for people with visual i
Infectious agents may be involved in atherothrombogenesis. The potential pathogenic pathway, however, remains unclear. We investigated the association between various infectious agents and lipoproteins known to have an atherogenic effect, We recruited 470 healthy blood donors and 238 patients with angiographically proven coronary heart disease (CHD), aged 40 to 68 years. Seropositivity to Chlamydi
Background Systemic inflammation has been suggested to underlie in part the elevated risk of arrhythmias and myocardial dysfunction during the first weeks after cardiac surgery. Recent transthoracic Doppler studies from our centre indicated increased basal coronary arterial flow in children 5 days after cardiopulmonary bypass surgery. In these children, we investigated whether the inflammatory med
