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AIMS: The onset of clinical type 1 diabetes (T1D) is preceded by the occurrence of disease-specific autoantibodies. The level of autoantibody titers is known to be associated with progression time from the first emergence of autoantibodies to the onset of clinical symptoms, but detailed analyses of this complex relationship are lacking. We aimed to fill this gap by applying advanced statistical mo
Twenty Apolipoprotein A-I (ApoA-I) variants are responsible for a systemic hereditary amyloidosis in which protein fibrils can accumulate in different organs, leading to their failure. Several ApoA-I amyloidogenic mutations are also associated with hypoalphalipoproteinemia, low ApoA-I and high-density lipoprotein (HDL)-cholesterol plasma levels; however, subjects affected by ApoA-I-related amyloid
The late stages of life, in most species including humans, are associated with a decline in the overall maintenance and health of the organism. This applies also to the hematopoietic system, where aging is not only associated with an increased predisposition for hematological malignancies, but also identified as a strong comorbidity factor for other diseases. Research during the last two decades h
Plants provide unique opportunities for learning by engaging all human senses. Recent laboratory studies have shown that infants use a combination of behavioural avoidance and social learning strategies to safely learn about plant properties from adults. Here we investigate how infants and their caregivers interact with plants in an outdoor garden as a first step towards examining the operation of
While both innate and adaptive immune system mechanisms have been implicated in resistance against the chytrid fungus Batrachochytrium dendrobatidis (Bd), studies on the role of specific MHC haplotypes on Bd infection are rare. Here, we studied variation in MHC Class IIB loci in the common toad Bufo bufo along a latitudinal gradient across Sweden. In general, Swedish toad populations had few MHC C
Islet transplantation is a minimally invasive β-cell replacement strategy. Islet transplantation is a reimbursed treatment in Norway. Here, we summarize the cost and clinical outcome of 31 islet transplantations performed at Oslo University Hospital (OUS) from January 2010 to June 2015. Patients were retrospectively divided into three groups. Thirteen patients received either one or two islet tran
Plasma cell dyscrasias, including monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma (MM), Waldenström macroglobulinemia (WM) and light chain AL amyloidosis, are characterized by clonal expansion of plasma cells which produce a vast amount of an immunoglobulin-derived M-protein. We noted that MGUS diagnosis often coincided with diagnoses of senile cataract and glaucoma and
Purpose: To set forth experiences in the context of the SERGS Pilot Curriculum—the first standardized educational program for robotic use in gynecological surgery—in terms of feasibility, effectiveness and potential for certification. Methods: The Society of European Robotic Gynecological Surgery (SERGS) outlined a Pilot Curriculum for standardized education in robot-assisted laparoscopic gynecolo
Context: Lynch syndrome (LS) is a cancer-predisposing syndrome caused by germline mutations in genes involved in DNA mismatch repair (MMR). Patients are at high risk for several types of cancer, but pituitary tumors have not previously been reported.Case: A 51-year-old man with LS (MSH2 mutation) and a history of colon carcinoma presented with severe Cushing disease and a locally aggressive pituit
OBJECTIVES: The influence of the amount and rate of weight loss on subsequently regaining weight and dropout from treatment in severely obese patients targeting 5% weight loss was investigated.METHODS: A total of 120 consecutive hospital patients with severe obesity (BMI: 42 ± 9 kg/m(2) ) participated in an inpatient program targeting 5% weight loss that involved goal setting, charting weight four
I TV-programmet »Uppdrag granskning« påstods nyligen (16 mars 2004) att det är livsviktigt för patienter med akut hjärtinfarkt att bo i närheten av rätt sjukhus. Frågan är när geografiska skillnader i dödlighet blir så pass stora och säkra att de har betydelse för den enskilda patienten. När man studerar skillnader i dödlighet mellan olika sjukhus bör man om möjligt också beakta landstingens roll.It is a known fact that the 1990s brought a decrease in mortality after myocardial infarction in Sweden but that differences in mortality rates following myocardial infarction still remain between the Swedish counties. Unresolved, however, are questions as to what these inter-county differences mean for the individual patient and what role hospital care plays in this context. We analysed all patie
Objective: To investigate the association between human herpesviruses and multiple sclerosis ( MS), as well as between measles virus and MS. Methods: The authors identified prospectively collected serum samples from 73 MS cases and retrospective sera from 161 MS cases in two population-based serum bank registers. Analyses of IgG antibody responses in cases and matched referents were performed for
This study aimed to examine the attitudes of social work students at Lund University towards autism and schizophrenia, with a focus on differences between the two diagnoses and how educational level and prior experience may explain variations in attitudes. The method the study used was a cross-sectional survey design and was conducted at the School of Social Work at Lund University, Sweden. Data w
This thesis develops a Fourier-feature DeepONet surrogate model for predicting two-dimensional steady laminar flow fields around a rotating triangular obstacle. The aim is to learn the mapping from the obstacle rotation angle to the corresponding pressure, x-velocity, and y-velocity fields. A CFD dataset containing 121 cases was generated using ANSYS Fluent, covering rotation angles from 0° to 120
Purpose: Altered auditory feedback research aims to identify methods to strengthen speakers’ awareness of their own voicing behaviors, diminish their perception of vocal fatigue, and improve their voice production. This study aims to compare the effects of two bone conduction devices that provide altered auditory feedback. Method: Twenty participants (19-33 years old, age: M [SD]=25.5 [3.85] years
Objective: This study aims to translate and cross-culturally adapt the throat scale of the Voice Handicap Index to the Brazilian Portuguese language.uracy. Material and Methods: This was performed in five phases translation, synthesis, back translation, review, and pretest. Fifty subjects participated in the pretest, of which 22 participants had chronic cough, 13 had laryngopharyngeal reflux, and
Föreliggande studie syftade till att undersöka prediktiva samband mellan konflikthanteringsstilar, emotionell intelligens och relationsnöjdhet i parrelationer och genomfördes i en svensk kontext. Följande forskningsfråga formulerades: I vilken utsträckning predicerar konflikthanteringsstilar och emotionell intelligens upplevd relationsnöjdhet hos individer i parrelationer? Studien baserades på en The present study aimed to examine predictive associations between conflict resolution styles, emotional intelligence, and relationship satisfaction in couple relationships, within a Swedish context. The following research question was formulated: To what extent do conflict resolution styles and emotional intelligence predict perceived relationship satisfaction amongst individuals in couple relati
Air quality is affected by airborne particles and gases such as PM2.5, volatile organic compounds (VOC), and nitrogen oxides (NOx), as well as environmental factors such as humidity and temperature, all of which influence human health and the spread of airborne diseases. While research grade air quality instruments provide accurate measurements, they are often large, expensive and difficult to uti
We present a model dielectric function composed of critical point functions in order to parameterize the temperature and wavelength dependencies of the dielectric function of InAs. This model is based on Adachi’s critical point model, with simple wavelength-dependent analytical functions whose parameters change linearly with temperature. The calculated dielectric function at room temperature is in
Utvärdering av psykologprogrammet Uppdrag och sakkunniggrupp Sakkunniggruppen (se sammansättning nedan) har haft i uppdrag att utifrån Lunds universitets gemensamma kriterier för kvalitetssäkring och med stöd av Samhällsvetenskapliga fakultetens anvisningar och instruktioner1 utvärdera Psykologprogrammet vid Samhällsvetenskapliga fakulteten. I uppdraget ingår att lyfta lärandemiljöns och utbildnin
https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2022-10/Sakkunnigutl%C3%A5tande%20psykologprogrammet.pdf - 2026-07-09
