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Neighborhoods and Child Mortality in an Industrializing Port Town: A Micro-Spatial Analysis of Landskrona,Sweden, 1890-1939

The turn of the twentieth century was a period of rapid decline in infant- and child mortality and a time of industrialization and urbanization in Sweden. It was also a period of growing social disparities in childhood mortality. The inequality in child survival was connected to a range of factors, including access to water- and sanitation, housing conditions, infant care, and possibly nutrition.

Neighborhoods and Child Mortality in an Industrializing Port Town: A Micro-Spatial Analysis of Landskrona,Sweden, 1890-1939

The turn of the twentieth century was a period of rapid decline in infant- and child mortality and a time of industrialization and urbanization in Sweden. It was also a period of growing social disparities in childhood mortality. The inequality in child survival was connected to a range of factors, including access to water- and sanitation, housing conditions, infant care, and possibly nutrition.

Oxy-ethane combustion : Measurements of the laminar burning velocities and kinetic insights into CO2 effects

Oxy-fuel combustion is regarded as an underpinning technology for carbon capture and utilization. Ethane (C2H6) is the primary non-methane component in natural gas and a fundamental C2 fuel. In this work, laminar burning velocities (LBV) of C2H6/O2/CO2 mixtures were measured using the heat flux method at atmospheric pressure, spanning initial temperatures of 308–348 K, equivalence ratios of 0.6–1.

Intergenerational effects of dietary changes on trait means and variance

Environmental stress can alter not only trait means but also trait variances - an often-overlooked evolvable feature with ecological and evolutionary relevance. We examine how dietary stress affects both the mean and variance of morphological and reproductive traits across two generations in clonal Daphnia. We manipulated maternal and offspring environments with high- (algae) or low-quality (cyano

The Swedish national guidelines on penile cancer

Objective: The Swedish national guidelines on penile cancer were first published in 2013. The objective of this study is to present the 2023 update of these guidelines and highlight the differences to the European Association of Urology (EAU) / American Association of Clinical Oncology (ASCO) guidelines on penile cancer. Material and methods: A review of the literature and a comparison to the EAU

Microbial associations and viruses on the risk of celiac disease (MAVRiC) : a longitudinal post-hoc case-cohort study

Celiac disease etiopathogenesis requires genetic predisposition and exposure to gluten, yet these factors alone are not sufficient. Larger longitudinal studies are needed to determine the role of time-varying infections and gut microorganisms. The aim was to design a celiac disease case-cohort longitudinal study using The Environmental Determinants of Diabetes in the Young (TEDDY) study. By age 3-

Stroke of Consistency : Streamlining Multicenter Protocols for Enhanced Reproducibility of Infarct Volumes in Preclinical Stroke Research

BACKGROUND: The discrepancy between experimental research and clinical trial outcomes is a persistent challenge in preclinical studies, particularly in stroke research. A possible factor contributing to this issue is the lack of standardization across experimental stroke models, leading to poor reproducibility in multicenter studies. This study addresses this gap by aiming to enhance reproducibili

Hur värderas avbrott i fjärrvärmeleveranser? – En analys av metod och kundperspektiv

Fjärrvärme är en central del av det svenska energisystemet och spelar en oumbärlig roll i samhället. Om ett avbrott skulle ske så leder det så småningom till sänkta temperaturer, och sänkta temperaturer kan medföra fara för hälsa, skador på system, och andra konsekvenser som exempelvis svårigheter att upprätthålla vårdverksamheter eller att upprätthålla det svenska försvaret. Det är alltså viktigtDistrict heating is a central part of the Swedish energy system and plays an indispensable role in society. If an interruption were to occur, it would eventually lead to lower temperatures, and lower temperatures could pose a health risk, damage to systems, and other consequences such as difficulties in maintaining healthcare operations or maintaining the Swedish defense. It is therefore important

A simulation-based framework for parametric energy renovation strategies in European buildings

This study presents a simulation-based framework for evaluating energy renovation strategies across European building typologies and climate zones. A factorial parametric approach was used to simulate over 800,000 combinations of envelope assemblies, HVAC systems, and shading controls for three archetypes (single-family, multi-family, office) across five European climate zones under both current a

Strong selective environments determine evolutionary outcome in time-dependent fitness seascapes

The impact of fitness landscape features on evolutionary outcomes has attracted considerable interest in recent decades. However, evolution often occurs under time-dependent selection in so-called fitness seascapes where the landscape is under flux. Fitness seascapes are an inherent feature of natural environments, where the landscape changes owing both to the intrinsic fitness consequences of pre

Ground-State Destabilization by Active-Site Hydrophobicity Controls the Selectivity of a Cofactor-Free Decarboxylase

Bacterial arylmalonate decarboxylase (AMDase) and evolved variants have become a valuable tool with which to access both enantiomers of a broad range of chiral arylaliphatic acids with high optical purity. Yet, the molecular principles responsible for the substrate scope, activity, and selectivity of this enzyme are only poorly understood to date, greatly hampering the predictability and design of

An international, expert-based, Delphi consensus document on controversial issues in the management of abdominal aortic aneurysms

Objective: As a result of conflicting, inadequate or controversial data in the literature, several issues concerning the management of patients with abdominal aortic aneurysms (AAAs) remain unanswered. The aim of this international, expert-based Delphi consensus document was to provide some guidance for clinicians on these controversial topics. Methods: A three-round Delphi consensus document was

Psychological risk and protective factors of immunity : a cross-cultural network analysis

Evidence shows psychological factors (e.g. stress) are linked to immunity, yet there is a lack of research investigating the complex interactions between psychological factors and immune function. Network analysis is useful to investigate complex interrelations between relevant health-related variables. This study applied network analyses to examine associations between psychological protective fa

Olfaction with legs—Spiders use wall-pore sensilla for pheromone detection

The sense of smell is a central sensory modality of most terrestrial species. However, our knowledge of olfaction is based on vertebrates and insects. In contrast, little is known about the chemosensory world of spiders and nothing about how they perform olfaction despite their important ecological role. The orb-weaving spider Argiope bruennichi lends itself to an in-depth study on olfaction as it

Genetic variation in caveolin-1 correlates with long-term pancreas transplant function

Pancreas transplantation is a successful treatment for a selected group of people with type 1 diabetes. Continued insulin production can decrease over time and identifying predictors of long-term graft function is key to improving survival. The aim of this study was to screen subjects for variation in the Caveolin-1 gene (Cav1), previously shown to correlate with long-term kidney transplant functi

Increased lung weight in fatal intoxications is not unique to opioid drugs

Fatal intoxications with opioids are known to be associated with an increased lung weight, as well as with brain and pulmonary edema and urinary retention. However, there is evidence to suggest that fatal intoxications with non-opioid substances are also associated with increased lung weight; however, the latter aspect has not been comprehensively analyzed. To determine to what extent opioid and n

Association between continuity of care in Swedish primary care and emergency services utilisation : a population-based cross-sectional study

Objective: The primary objective of this study was to determine the association between longitudinal continuity of care (CoC) in Swedish primary care (PC) and emergency services (ES) utilisation.Study design: A cross-sectional analysis of longitudinal population data. Setting. PC centres, out-of-hours PC facilities and emergency departments (EDs) in Blekinge County in southern Sweden. Subjects: Pe

Remote sensing-based biomass estimation of dry deciduous tropical forest using machine learning and ensemble analysis

Forests play a vital role in maintaining the global carbon balance. However, globally, forest ecosystems are increasingly threatened by climate change and deforestation in recent years. Monitoring forests, specifically forest biomass is essential for tracking changes in carbon stocks and the global carbon cycle. However, developing countries lack the capacity to actively monitor forest carbon stoc

Fusion maturation over time in operated on adolescent idipathic scoliosis – a low dose CT study up to 5 years

Purpose: The aim of this study was to evaluate bony fusion with Low Dose CT (LDCT) over time following posterior scoliosis surgery in an all screw construct in patients with AIS with special focus on whether the spinal fusion process continue to develop beyond 2 years after scoliosis surgery and to evaluate if LDCT is an adequate radiological method to assess fusion maturation. Methods: Twenty fiv

Intracranial hemorrhage before start of prophylaxis in children with hemophilia : incidence, timing, and potential for prevention

Children with hemophilia have a significantly higher risk of intracranial hemorrhage (ICH) compared to the normal population. Prophylaxis reduces the risk of ICH and earlier initiation of prophylaxis may now be feasible, especially in hemophilia A (HA). The aim of the study is to explore the potential for preventing ICH by earlier start of prophylaxis by assessing the natural course of ICH before