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Subalpine gully-head ribbon fens of the Lammerlaw and Lammermoor Ranges, Otago, New Zealand

Vegetation patterns of subalpine gully-head mires were investigated in the flat-topped Lammerlaw and Lammermoor Ranges, South Island, New Zealand. Two intensively studied mires each consist of a series of peaty terraces and scarps. Terraces may contain pools, elongated downslope in the narrow, lower altitude mire, but across slope in the broader, upper mire. A crest occurs on some terrace lips, an

An X-ray diffraction study of alterations in bovine lung surfactant bilayer structures induced by albumin.

Lung surfactant (LS) is an extra-cellular lipid-protein system responsible for maintaining low surface tension in the lung and alveolar stability. Serum proteins cause dysfunction of this material, e.g. in adult respiratory distress syndrome (ARDS). BLES is a clinically used LS consisting of most of the lipids and associated proteins from bovine lung lavage. Aqueous phases of BLES at 30% and 70% h

Coreceptor usage of sequential isolates from cynomolgus monkeys experimentally infected with simian immunodeficiency virus (SIVsm)

Sequential isolates from eight cynomolgus monkeys experimentally infected with Simian immunodeficiency virus (SIVsm, of sooty mangabey origin) were tested for coreceptor use in the human osteosarcoma indicator cell line, GHOST(3), expressing CD4 and one or another of the chemokine receptors CCR3, CCR5, CXCR4, BOB, or the orphan receptor Bonzo. The indicator cell line carries the human immunodefici

The Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin and cell surfaces via positively charged amino acids in CCP1-2.

The Kaposi's, sarcoma-associated herpesvirus (KSHV) complement control protein (KCP) inhibits the human complement system, and is similar in structure and function to endogenous complement inhibitors. Other inhibitors such as C4d-binding protein and factor H, as well as the viral homologue vaccinia virus complement control protein are known to bind heparin and, for the two latter, also to glycosam

Prognosis in elderly men with screening-detected abdominal aortic aneurysm

OBJECTIVES: To study the natural course of screening-detected symptomless abdominal aortic aneurysm (AAA) in elderly men. SETTING: Malmo, a city in southern Sweden with 230,000 inhabitants and a single referral hospital. MATERIALS: 423 seventy-four-year-old men, randomly selected from the population and belonging to the prospective population study "Men born in 1914", were invited. 343 underwent A

District Heating Expansion Strategies in Detached House Areas

District heating is well expanded in the residential areas in Sweden, although not in detached house areas, where it is often impaired with problems of low heat density, large heat losses and high construction costs. However, due to the changes on the electricity market, increased environmental concerns and technological improvements, the detached houses’ sector is a potential market for district

A rigid barrier between the heart and sternum protects the heart and lungs against rupture during negative pressure wound therapy.

OBJECTIVES: Right ventricular heart rupture is a devastating complication associated with negative pressure wound therapy (NPWT) in cardiac surgery. The use of a rigid barrier has been suggested to offer protection against this lethal complication, by preventing the heart from being drawn up and damaged by the sharp edges of the sternum. The aim of the present study was to investigate whether a ri

The Triglyceride Content in Skeletal Muscle Is Associated with Hepatic But Not Peripheral Insulin Resistance in Elderly Twins.

Context and Objective:Total muscle triglyceride (MT) content has been associated with insulin resistance. We investigated the predictors and impact of MT on relevant metabolic parameters including peripheral and hepatic insulin resistance in elderly twins.Design and Participants:Seventy-four elderly same-sex twins underwent hyperinsulinemic euglycemic clamps preceded by an iv glucose tolerance tes

Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death.

Fibroblast growth factor 8 (FGF-8) is expressed in a large proportion of breast cancers, whereas its level in normal mammary gland epithelium is low. Previous studies have shown that FGF-8b stimulates breast cancer cell growth in vitro and in vivo. To explore the mechanisms by which FGF-8b promotes growth, we studied its effects on cell cycle regulatory proteins and signalling pathways in mouse S1

The immunomodulatory properties of C-Med 100 an extract of the plant Uncaria tomentosa

Popular Abstract in Swedish C-Med 100, en naturmedicin med immunomodulerande egenskaper Vårt immunsystem skyddar oss mot infektioner från bakterier, virus och parasiter. För att detta ska fungera behövs många olika egenskaper och idag delas immunsystemet in i två delar, en ospecifik och en specifik. Den ospecifika delen består av hud, slemhinnor, magsyra och olika celler som snabbt tar sig till etExtracts from the bark of the vine Uncaria tomentosa have anti-inflammatory, antiviral, antimutagenic and antioxidant effects. In this study, we evaluate the effects of an Uncaria tomentosa extract, denoted C-Med 100, on the cellular level of the immune system both in vivo and in vitro. Our results indicated that lymphocytes had significantly prolonged half life after in vivo supplementation with

Familial and Hereditary Prostate Cancer

Popular Abstract in Swedish Introduktion: 1) Prostatacancer Prostatakörteln Prostatan, eller blåshalskörteln, är belägen strax nedanför urinblåsan hos män, där den omsluter urinrörets översta del. Denna, i normala fall valnötsstora körtel, producerar ett sekret som utgör en del av sädesvätskan. Hos yngre män uppstår ibland infektioner i prostatakörteln. Många äldre män får en godartad prostatafThis thesis is based on research concerning epidemiological, clinical, and psychological aspects of familial and hereditary prostate cancer. Epidemiology: Male first-degree relatives of prostate cancer patients had a three-fold increased prostate cancer risk. The risk was higher for relatives of younger patients than for relatives of older patients, most likely due to the effect of the higher pre

John Philoponus against Cosmas Indicopleustes : A Christian Controversy on the Structure of the World in Sixth-Century Alexandria

The scope of this study is to compare John Philoponus and Cosmas Indicopleustes, two Christian individuals of different backgrounds and belonging to different fractions of the Church in the turbulent time for the Church in sixth century Alexandria. Any Christian is likely to feel the need to define how the tenets of his or her faith relate to contemporary science. As long as Christianity has exis

Fe II fluorescence in symbiotic stars

Fe 0 fluorescence by PAR has been investigated in eight symbiotic starshaving a wide range in temperature of the hot component and orbitalperiod. The data used are spectra obtained from the IUE archive. Allpumping lines investigated in this work are in the short wavelengthregion of IUE (1200-2000 Å), except for He 0 λ 1084.942 andO 0 λ 1032.041. The resulting Fe 0 fluorescence lines are mainlyin t

Protocol and Methodology of the Stroke in Young Fabry Patients (sifap1) Study: A Prospective Multicenter European Study of 5,024 Young Stroke Patients Aged 18-55 Years

Background: Stroke in the young has not been thoroughly investigated with most previous studies based on a small number of patients from single centers. Furthermore, recent reports indicate that Fabry disease may be a significant cause for young stroke. The primary aim of our study was to determine the prevalence of Fabry disease in young stroke patients, while the secondary aim was to describe pa

Gas6 is complexed to soluble tyrosine kinase receptor Axl in human blood.

Summary Background: The vitamin K-dependent Gas6 protein (product of growth arrest specific gene 6) binds to, and activates the TAM receptor tyrosine kinases Tyro3, Axl, and Mer. Gas6 and the TAM receptors have been suggested to be important for primary platelet functions, but Gas6 cannot be found in human platelets. However, Gas6 is present in human plasma at a concentration of around 0.2 nM, whi

The new library user in Sweden: A LibQUAL+? study at Lund University

Purpose: To examine how the library user emerges in the context of the LibQUAL+ application in Sweden in 2004. Design/methodology/approach: The paper examines the following aspects: how the information control dimension is depicted in the results of the Swedish participants; how the information control dimension compares between the Swedish implementation and other libraries; the "new user" as he

Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens

Nidogen-1 binds several basement membrane components by well-defined, domain-specific interactions. Organ culture and gene targeting approaches suggest that a high-affinity nidogen-binding site of the laminin gamma1 chain (y1III4) is important for kidney development and for nerve guidance. Other proteins may also bind gamma1III4, although human nidogen-2 binds poorly to the mouse laminin gamma1 ch

Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation

Bone morphogenetic proteins (BMPs) are pleiotropic secreted proteins, structurally related to transforming growth factor (TGF)-beta and activins. BMPs play pivotal roles in the regulation of embryonic lung development and branching of airways and have recently been considered to influence inflammatory processes in adults due to their chemotactic activity on fibroblasts, myocytes, and inflammatory

A murine antibacterial orthologue to human bactericidal/permeability-increasing protein (BPI) is expressed in testis, epididymis, and bone marrow.

The bactericidal/permeability-increasing protein (BPI), stored in human neutrophil granulocytes, is cytotoxic against Gram-negative bacteria. Several genes related to BPI cluster on human chromosome 20 and on mouse chromosome 2, but expression and characterization of a BPI ortholog in the mouse have not been reported. We asked whether BPI is structurally and functionally conserved between humans a

Families' lived experience one year after a child was diagnosed with type 1 diabetes

Aim. This paper is a report of a study to elucidate families' lived experience of diabetes one year after a child was diagnosed with type 1 diabetes. Background. The incidence of type 1 diabetes is rapidly increasing worldwide, with a shift towards younger age groups. This illness is treated by means of an intensive management regimen that often disrupts the child's usual activities and requires d