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Popular Abstract in Swedish Högt blodtryck, hypertoni, är en folksjukdom som ökar risken att insjukna i slaganfall och hjärtinfarkt. I flertalet fall är orsaken till hypertoni okänd och man talar då om primär hypertoni. Mellan 30 och 60% av blodtrycksvariationen i befolkningen bestäms av genetiska faktorer medan resten beror på omgivningsfaktorer. Primär hypertoni uppkommer sannolikt på grund av sGenetic factors are of importance for the development of primary hypertension (HT). Intrauterine growth retardation, salt sensitivity and insulin resistance are all characteristic features of individuals prone to develop HT. Monogenic forms of hypertension such as Liddle´s syndrome (LS) and Apparent Mineralocorticoid Excess (AME), and hypotension such as Gitelman´s syndrome (GIT) have recently bee

Popular Abstract in Swedish Den här avhandlingen handlar om studenter som samtalar och samarbetar i små grupper i en nätbaserad kurs. Studien har ett intresse av att beskriva och förstå de dialogiska processer, som uppstår i ett autentiskt nätbaserat samtal, vilket pågår under lång tid. Det handlar bland annat om att studera, hur deltagarna använder sig av de meningserbjudande, i form av deltagarnThis thesis investigates students' dialogue and collaboration when working in small groups in a netbased course. The aim is to describe and shed light on student's dialogue and collaboration in a computer-mediated communication working with a problem oriented task. Thus, the interest lies in student's engagement in the learning situation rather than on the learning outcomes. The research was carr

In this thesis the connection between coherence and reliability is investigated. The question may be phrased as follows: does the fact that a set of testimonies is coherent imply that the witnesses who have reported these testimonies are reliable? The same question may also be expressed in terms of beliefs: does the fact that a set of beliefs is coherent imply that the beliefs were reliably produc

At Forsmark, ca. 120 km north of Stockholm in central Sweden, ductile high-strain belts with WNW to NW trend anastomose around tectonic lenses with an inferred lower degree of ductile strain. Previous studies of ductile deformation zones with WNW to NW trend, elsewhere in the western part of the Svecofennian orogen in central Sweden, have yielded estimates for the timing of at least one phase of d

The toxic haptophyte Prymnesium parvum regularly forms fish-killing blooms in inland brackish water bodies in the south-central USA. Along the Texas coast smaller blooms have occurred in isolated areas. There appears to be an increasing risk that harmful P. parvum blooms will propagate into open coastal waters with implementation of future water plans. These plans will include increased interbasin

AIM: To investigate the mechanism of interleukin (IL)-6 secretion through blocking the IL-17A/IL-17A receptor (IL-17RA) signaling pathway with a short hairpin RNA (shRNA) in hepatic stellate cells (HSCs) in vitro. METHODS: HSCs were derived from the livers of adult male Sprague-Dawley rats. IL-6 expression was evaluated using real-time quantitative polymerase chain reaction and enzyme linked immun

The simulation of current and projected wildfires is essential for predicting crucial aspects of vegetation patterns, biogeochemical cycling as well as pyrogenic emissions across the African continent. This study uses a data-driven approach to parameterize two burned area models applicable to dynamic vegetation models (DVMs) and Earth system models (ESMs). We restricted our analysis to variables f

Relationships among allotetraploid marsh orchids collectively assignable to Dactylorhiza majalis s.l. are exceptionally complex because of multiple origins, secondary hybridization with each other, and with their parental lineages, local adaptation, and genomic reorganization processes, all extending through time and space. We sampled 34 populations from Britain and Ireland in an attempt to simult

Alcohol and tobacco consumption are closely correlated and published results on their association with breast cancer have not always allowed adequately for confounding between these exposures. Over 80% of the relevant information worldwide on alcohol and tobacco consumption and breast cancer were collated, checked and analysed centrally. Analyses included 58515 women with invasive breast cancer an

Adduct formation between cationic reagents and targets on DNA are facilitated by the ability of DNA to attract cations to its surface. The electrostatic interactions likely provide the basis for the documented preference exhibited by cisplatin and related compounds for nuclear DNA over other cellular constituents. As an extension of a previous communication, we here present an investigation illust

The vegetation history of the Faroe Islands has been investigated in numerous studies all broadly showing that the early-Holocene vegetation of the islands largely consisted of fellfield with gravely and rocky soils formed under a continental climate which shifted to an oceanic climate around 10,000 cal yr BP when grasses, sedges and finally shrubs began to dominant the islands. Here we present da

The recent and fossil pollen data obtained under the frame of the multi-disciplinary international El'gygytgyn Drilling Project represent a unique archive, which allows the testing of a range of pollen-based reconstruction approaches and the deciphering of changes in the regional vegetation and climate. In the current study we provide details of the biome reconstruction method applied to the late

Popular Abstract in Swedish Fotosyntesen är nödvändig för vårt liv på jordklotet. Fotosyntes utförs huvudsakligen av gröna växter och dessutom av vissa bakterier. Dessa organismer absorberar energin i solljuset och omvandlar den till kemisk energi i form av till exempel kolhydrater och fett som vi människor och djur sedan kan förbränna och utvinna energi ifrån. Fotosyntesen utförs av ett flertal pPSII catalyses the light-induced water splitting process which leads to electron transfer through the thylakoid membrane and formation of energy rich molecules. Several redox components including a Mn4Ca, an amino acid residueYZ, two special Chl molecules P680, two Pheo and two quinone molecules participate in this process. Another component of PSII which interacts magnetically with Mn4Ca is D2-Ty

The capacity of somatic cells and pollen grains or microspores to undergo embryogenesis is an important property used in improvement and regeneration of plants. Furthermore, somatic embryogenesis as well as pollen embryogenesis show many similarities with zygotic embryogenesis and are, thus, good model systems. Pollen suspensions of tobacco (Nicotiana tabacum L.) contain a mixture of embryogenic a

Popular Abstract in Swedish Denna avhandling är en sammanläggningsavhandling som består av fyra artiklar inom arbetsmarknadsområdet. Den första artikeln behandlar en personalförstärkning till arbetsförmedlingen. Metoden har bestått i att jämföra tre arbetsförmedlingskontor som erhållit stora personalförstärkningar med tre kontor som inte fått någon personalförstärkning alls. Resultaten tyder på atThis thesis results from four research projects. The issues addressed in the projects are different types of labour market information problems. The purpose of the first article is to contribute to a better empirical under- standning of how an increase of staff at the Public Employment Service affects job seekers. In 1987, the Swedish Government decided to grant the Labour Market Administration ex

Popular Abstract in Swedish Varför beslutar politiker ibland att vidta till synes effektlösa åtgärder? Varför uppstår ibland stora politiska konflikter i små frågor? I vanliga fall vidtar man en politisk åtgärd därför att man eftersträvar det konkreta resultatet av åtgärden. Symbolpolitik är när en politisk fråga blir viktig, inte beroende på vad den konkret innebär och leder till, utan på grund aSymbolic politics is the degree to which political decision-making is motivated, not by the tangible aspects of the decision, but by the interpretation of what the decision represents symbolically. While symbolic politics is widely recognized as an important aspect of political decision-making, the phenomenon is insufficiently explored in political science. The first aim of the present dissertatio

Hematopoietic stem cells (HSCs) are primitive tissue-specific somatic stem cells, responsible for the maintenance and replenishment of the bone marrow (BM) and subsequently the entire blood system. The never-ending ability to differentiate into all the mature hematopoietic lineages makes these HSCs attractive candidates for use in future regenerative medicine. HSCs are balanced between different f

OBJECTIVE: Coronary artery disease is a prevalent cause of morbidity and mortality in diabetes. Little is known about insulin-like growth factor-I receptors (IGF-IR) and insulin receptors (IR) in human coronary endothelium. Our aim was to characterize IGF-IR and IR in human coronary artery endothelial cells (HCAEC). DESIGN: Cultured human coronary artery endothelial cells were used. Gene expressio

Objective: To determine if the correlation between magnitude of creatine kinase-myocardial band release after coronary artery bypass surgery and 6-month mortality is comparable to that of patients admitted with an acute coronary syndrome. Methods: The GUARDIAN trial tested the efficacy of cariporide, an Na+/H+ exchange inhibitor, on reduction of myocardial ischemia or death in high-risk patients.

Popular Abstract in Swedish Ökningen av växthusgaser i atmosfären har orsakat en global temperaturhöjning. Afrika anses vara en av de kontinenter som kan komma att bli mest utsatta av effekterna kring ökande temperaturer med mer frekventa torkor som följd. Satellitdata ger oss möjligheten att uppskatta biomassa över stora områden vilket i sin tur kan leda till att öka vår förståelse kring hur utbyWith the challenges Africa faces with respect to the predicted warming due to climate change, the continents role in the global carbon cycle has been increasingly recognized. Earth observing satellites have played a significant role in the study of vegetation, particularly in Africa where climate stations are sparse. Satellite data can provide the means to map plant primary production for monitori