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Skin barrier damage and subsequent development of harmful microbiota contribute to conditions such as wound infections, atopic dermatitis and chronic wounds, which impact millions of people globally and pose a significant economic burden on healthcare systems. Established microbial sampling methods, such as swabs and tissue biopsies, provide limited information on the spatial distribution of bacte

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Evidence shows psychological factors (e.g. stress) are linked to immunity, yet there is a lack of research investigating the complex interactions between psychological factors and immune function. Network analysis is useful to investigate complex interrelations between relevant health-related variables. This study applied network analyses to examine associations between psychological protective fa

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Background: Recent studies indicate the need to examine how the gut microbiota–brain axis is implicated in pain, sensory reactivity and gastro-intestinal symptoms in autism spectrum disorder (ASD), but no scale exists that assesses all these constructs simultaneously. Methods: We created a pool of 100 items based on the real-world experience of autistic people, and a multidisciplinary team and sta

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Objective: The primary objective of this study was to determine the association between longitudinal continuity of care (CoC) in Swedish primary care (PC) and emergency services (ES) utilisation.Study design: A cross-sectional analysis of longitudinal population data. Setting. PC centres, out-of-hours PC facilities and emergency departments (EDs) in Blekinge County in southern Sweden. Subjects: Pe

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The sense of smell is a central sensory modality of most terrestrial species. However, our knowledge of olfaction is based on vertebrates and insects. In contrast, little is known about the chemosensory world of spiders and nothing about how they perform olfaction despite their important ecological role. The orb-weaving spider Argiope bruennichi lends itself to an in-depth study on olfaction as it

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Background: The existence of a “minority tax,” defined as the burden of extra responsibilities placed on minorities relative to non-minorities of the same position, has been documented across various fields, including and beyond medicine. This study sought to quantify the types and extent of the minority tax faced by minority orthopaedic surgeons, as well as evaluate the degree to which this work

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Purpose: The aim of this study was to evaluate bony fusion with Low Dose CT (LDCT) over time following posterior scoliosis surgery in an all screw construct in patients with AIS with special focus on whether the spinal fusion process continue to develop beyond 2 years after scoliosis surgery and to evaluate if LDCT is an adequate radiological method to assess fusion maturation. Methods: Twenty fiv

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Forests play a vital role in maintaining the global carbon balance. However, globally, forest ecosystems are increasingly threatened by climate change and deforestation in recent years. Monitoring forests, specifically forest biomass is essential for tracking changes in carbon stocks and the global carbon cycle. However, developing countries lack the capacity to actively monitor forest carbon stoc

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Background: One of the preanalytical factors that can affect the results of arterial blood gas (ABG) analysis is the time from sample collection to analysis. A delay in analysis may affect the results due to factors such as ongoing cellular metabolism within the blood sample, gas exchange between the blood sample and the environment, and temperature changes. ABG analysis can be delayed for various

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Major Depression (MD) and General Anxiety Disorder (GAD) are the most common mental health disorders, which typically are assessed quantitatively by rating scales such as PHQ-9 and GAD-7. However, recent advances in natural language processing (NLP) and machine learning (ML) have opened up the possibility of question-based computational language assessment (QCLA). Here we investigate how accurate

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Children with hemophilia have a significantly higher risk of intracranial hemorrhage (ICH) compared to the normal population. Prophylaxis reduces the risk of ICH and earlier initiation of prophylaxis may now be feasible, especially in hemophilia A (HA). The aim of the study is to explore the potential for preventing ICH by earlier start of prophylaxis by assessing the natural course of ICH before

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The increasing prevalence of mental health problems coupled with limited access to professional support has prompted exploration of technological solutions. Large Language Models (LLMs) represent a potential tool to address these challenges, yet their capabilities in psychotherapeutic contexts remain unclear. This study examined the competencies of current LLMs in psychotherapy-related tasks inclu

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Objectives: Coagulation test results may be affected by hemolysis, icterus and/or lipemia (HIL). Detailed guidelines for HIL-management are missing, both for manual and automatic HIL-checks. The aim of this survey was to provide an overview of the practical procedures for the detection and handling of HIL-samples used by laboratories in Europe in the context of coagulation testing. Methods: A Surv

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The turn of the twentieth century was a period of rapid decline in infant- and child mortality and a time of industrialization and urbanization in Sweden. It was also a period of growing social disparities in childhood mortality. The inequality in child survival was connected to a range of factors, including access to water- and sanitation, housing conditions, infant care, and possibly nutrition.

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The turn of the twentieth century was a period of rapid decline in infant- and child mortality and a time of industrialization and urbanization in Sweden. It was also a period of growing social disparities in childhood mortality. The inequality in child survival was connected to a range of factors, including access to water- and sanitation, housing conditions, infant care, and possibly nutrition.

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Oxy-fuel combustion is regarded as an underpinning technology for carbon capture and utilization. Ethane (C2H6) is the primary non-methane component in natural gas and a fundamental C2 fuel. In this work, laminar burning velocities (LBV) of C2H6/O2/CO2 mixtures were measured using the heat flux method at atmospheric pressure, spanning initial temperatures of 308–348 K, equivalence ratios of 0.6–1.

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Treatment of bladder cancer patients depends on precise diagnosis. Molecular subtyping by gene expression profiling may contribute substantially to subclassification of bladder cancer. Several classification systems have been proposed. Most of these base their classification on whole biopsy features, and molecular subtypes are therefore often defined by a combination of features from the cancer ce

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INTRODUCTION: Patient simulation can be useful for medical students in developing communication skills for vulnerable situations. Three participants are primarily involved in the patient simulation activities: the student, the simulated patient (SP), and the teacher. We here aimed to explore these participants' perceptions of learning in a patient simulation scenario.METHODS: We conducted individu

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Background: Because overweight and obesity are still increasing and prevention of childhood obesity is more likely to be effective when initiated in preschool children, the Child Health Service in the south of Sweden developed a structured child-centred health dialogue model targeting all 4-year-old children and their families. The aim of this study was to describe parents' recalled experiences of

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BackgroundEvidence suggests that lifestyle activities impact cognitive and mental health in older populations. However, how lifestyle factors are associated with one another, and which factors are most important for cognitive function and mental health has received comparatively little attention.DesignBayesian-Gaussian network analysis was used to investigate unique associations between mental act