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Concentration of citrus fruit juices in membrane pouches with solar energy Part 1 : How solar drying setup and juice pretreatment determine the drying flux

The aim of this study was to investigate how solar drying setup and choice of juice pretreatment determine the drying flux in a fruit juice concentration process called solar assisted pervaporation. With this process, hygienic membrane pouches and solar energy are used to concentrate and preserve fruit juices. In this study, the feasibility of concentrating citrus (tangerine) juice into marmalade

Diagnostic accuracy of troponin T measured ≥6h after symptom onset for ruling out myocardial infarction

Objectives: Guidelines recommend a single high-sensitivity cardiac troponin T (hs-cTnT) ≤14 ng/L measured ≥6 h after chest pain onset combined with a GRACE score <140 and the patient being pain-free for ruling out myocardial infarction (MI). There is however little data on the performance of this strategy. We therefore aimed to evaluate the diagnostic accuracy of a hs-cTnT ≤14 ng/L measured ≥6 h a

Sense of Coherence and the association with sociodemographics and disability related factors in persons with late effects of polio

BACKGROUND: Sense of Coherence (SOC) is important for successful adaptation in persons with life-long disabilities. A previous study has shown that persons with Late Effects of Polio (LEoP) have a level of SOC indicating that they generally have the ability to understand, handle and being motivated when dealing with stressful events and problems arising in their lives. However, no study has explor

Application of soft computing and evolutionary algorithms to estimate hydropower potential in multi-purpose reservoirs

Hydropower is a clean and efficient technology for producing renewable energy. Assessment and forecasting of hydropower production are important for strategic decision-making. This study aimed to use machine learning models, including adaptive neuro-fuzzy inference system (ANFIS), gene expression programming, random forest (RF), and least square support vector regression (LSSVR), for predicting hy

A Functional Genomic Screen Identifies the Deubiquitinase USP11 as a Novel Transcriptional Regulator of ERα in Breast Cancer

Approximately 70% of breast cancers express estrogen receptor α (ERα) and depend on this key transcriptional regulator for proliferation and differentiation. While patients with this disease can be treated with targeted antiendocrine agents, drug resistance remains a significant issue, with almost half of patients ultimately relapsing. Elucidating the mechanisms that control ERα function may furth

Prolonged stimulation with low-intensity ultrasound induces delayed increases in spontaneous hippocampal culture spiking activity

Ultrasound is a promising neural stimulation modality, but an incomplete understanding of its range and mechanism of effect limits its therapeutic application. We investigated the modulation of spontaneous hippocampal spike activity by ultrasound at a lower acoustic intensity and longer time scale than has been previously attempted, hypothesizing that spiking would change conditionally upon the av

The Impact of Urbanization-Induced Land Use Change on Land Surface Temperature

Rapid urbanization can change local climate by increasing land surface temperature (LST), particularly in metropolitan regions. This study uses two decades of remote sensing data to investigate how urbanization-induced changes in land use/land cover (LULC) affect LST in the Beijing Region, China. By focusing on the key issue of LST and its contributing variables through buffer zones, we determined

Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort

We aimed to investigate the genetic associations of neuropathic pain in a deeply phenotyped cohort. Participants with neuropathic pain were cases and compared with those exposed to injury or disease but without neuropathic pain as control subjects. Diabetic polyneuropathy was the most common aetiology of neuropathic pain. A standardised quantitative sensory testing protocol was used to categorize

Prenatal exposure to organochlorine pesticides and polychlorinated biphenyls and risk of testicular germ cell cancer later in life

Introduction: Exposure to environmental chemicals during fetal development may increase the risk of testicular germ cell cancer (TGCC), but few studies have tested the hypothesis. We focused on organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), previously investigated in relation to other male reproductive health outcomes. Methods: We conducted a nested case-control study of 33

When irony is faster than its literal control : The role of mindreading during irony comprehension

Irony is a heavily context-dependent pragmatic phenomenon. But what is it about context that facilitates or blocks irony comprehension? Based on the echoic account, we suggest that a context facilitates irony comprehension when it makes manifest a speaker's intentions and attitude, i.e., when a context makes it easy for participants to engage their mindreading abilities. In two pre-registered self

Psychometric properties of the Swedish version of the SNAP-IV rating scale parent form in a birth cohort of 11-year-old children

OBJECTIVE: The primary aim of this study was to confirm the internal consistency and factor structure of the Swedish version of the Swanson-Nolan-Pelham scale fourth edition (SNAP-IV) for parents and to examine its clinical utility for identifying children diagnosed with attention deficit/hyperactivity disorder (ADHD).MATERIALS AND METHODS: Parents of 11-year-old children from a birth cohort in th

Artificial Intelligence-guided Total Opacity Scores and Obstructive Sleep Apnea in Adults with COVID-19 Pneumonia

OBJECTIVE: We previously demonstrated that artificial intelligence (AI)-directed chest computed tomography (CT)-based total opacity scores (TOS) are associated with high-risk obstructive sleep apnea (OSA) based on the Berlin Questionnaire. In the current study, we examined the association between TOS severity and OSA severity based on polysomnography (PSG) recordings among participants with a hist

Land-use impacts on crop yield : direct and indirect roles of arthropods and associated ecosystem services in European farmland

Context: Land-use intensification to increase yields is often detrimental to biodiversity undermining the provision of ecosystem services. However, it is questionable if ecosystem service providers contribute to ecological intensification by achieving the same or higher yields than conventional high-intensity agriculture. Objectives: In this study, we aimed to disentangle the effects of local and

Relationships of hsCRP to High-Risk Vulnerable Plaque After NSTEMI : Insights From the PROSPECT II Trial

Background: Inflammation is a driver of atherosclerosis and susceptibility to cardiovascular events. Objectives: The authors sought to evaluate whether high-sensitivity C-reactive protein (hsCRP) levels are associated with the prevalence of high-risk coronary plaques in patients with non–ST-segment elevation myocardial infarction (NSTEMI). Methods: PROSPECT (Providing Regional Observations to Stud

Management of cerebrospinal fluid leak during endoscopic pituitary surgery

Objective: Dural opening and closures are major steps in endoscopic pituitary surgery. Restoring the normal anatomy at the end of the procedure creates a natural barrier between the intrasellar compartment and the sinonasal cavity. Methods: In this study, we present a relatively simple dural opening and closure technique for endoscopic pituitary surgery. This technique provides a better alternativ

Development and Validation of a Risk Prediction Model for Esophageal Squamous Cell Carcinoma Using Cohort Studies

INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure to readily available risk factors to identify high-risk individuals of ESCC.METHODS: Competing risk regression modeling was used to develop a risk prediction model. Individuals' ab

"Då rökte jag på. Sen började jag lite med tjack och sånt också." :en studie om hur ungdomars missbruk påverkar familjen

The purpose of our report was to analyze the effects of youth drug abuse on the families concerned. Youth drug abuse made us wonder about the effects on the family as a whole, of those involved with drug abuse. To answer this question, we decided to employ an empiric study in the form of interviews with four teenagers, five parents and four drug counselors. Because our intent was to understand rat

"Synpunkter på EU-harmoniseringen av svensk upphovsrättslagstiftning". En uppsats om ändringarna i URL 2005, (Lag (1960:729) om upphovsrätt till litterära och konstnärliga verk) och hur de uppfattas av olika organisationer verksamma inom området.

Copyright is a part of the intellectual property rights. This ancient occurrence became during 19th century observed by the legislation. Great economical interests and values made it necessary to create rules concerning how the exploitation would take place. Several important conventions were created during this century. For example, the Parisconvention (1883) and the Bernconvention (1886). During

Alcohol intake and endogenous sex hormones in women : Meta-analysis of cohort studies and Mendelian randomization

Background: The mechanisms underlying alcohol-induced breast carcinogenesis are not fully understood but may involve hormonal changes. Methods: Cross-sectional associations were investigated between self-reported alcohol intake and serum or plasma concentrations of estradiol, estrone, progesterone (in premenopausal women only), testosterone, androstenedione, dehydroepiandrosterone sulfate, and sex