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Aims/hypothesis: The study evaluated whether glucagon secretion is regulated by changes in insulin sensitivity under normal conditions. Materials and methods: A total of 155 healthy women with NGT (aged 53-70 years) underwent a glucose-dependent arginine-stimulation test for evaluation of glucagon secretion. Arginine (5 g) was injected i.v. under fasting conditions (plasma glucose 4.8 +/- 0.1 mmol
Purpose: To evaluate against Monte-Carlo the performance of various dose calculations algorithms regarding lung turnout coverage in stereotactic body radiotherapy (SBRT) conditions. Materials and methods: Dose distributions in virtual lung phantoms have been calculated using four commercial Treatment Planning System (TPS) algorithms and one Monte Carlo (MC) system (EGSnrc). We compared the perform
Background. Many patients with heart failure have generalized wasting, referred to as cardiac cachexia. This leads to skeletal muscle wasting, impaired mobility, reduced functional capacity and poor prognosis. Patients with heart failure have symptoms that can affect their food intake, for example breathing difficulties, fatigue, nausea, loss of appetite, early feeling of fullness and ascites. The
Popular Abstract in Swedish Nuklearmedicin bygger på användning av radioaktiva spårämnen, enligt principen av George de Hevesy, för kartläggning av global och regional funktion hos organ eller patologisk vävnad. Nuklearmedicin inkluderar även användningen av ”Magic bullet”-konceptet enligt Ehrlich där en molekyl används som bärare av radionuklider för att få en radiobiologisk terepeutisk effekt påNuclear medicine is based on the radiotracer principle of George de Hevesy and the magic bullet concept by Ehrlich and focuses on the diagnosis, the treatment of diseases and the investigation of normal states within the human body using radiopharmaceuticals. A radiopharmaceutical is an atom or a chemical compound in which one or several atoms are replaced with a radionuclide. Several diagnostic a
Popular Abstract in Swedish Alla levande celler har förmåga att känna av och på olika sätt anpassa sig till sin omgivning, antingen de ensamma utgör en hel organism eller är en av många miljarder celler i ett stort djur. Varje enskild cell kan bara ta emot en begränsat mängd olika sorters signaler och bara reagera på ett likaledes begränsat antal sätt. Den en- eller fåcelliga organismen är därmed The G protein-coupled receptors form one of the largest families of proteins involved in signalling between cells. It contains receptors for molecules as diverse as biogenic amines, glycoproteins and enzymes. The manuscripts included in this thesis together describe the initial characterisation of a previously unknown receptor of this class. A DNA fragment was cloned from a mouse genomic library.
This paper presents the study of a mid-sized semi-closed oxy-fuel combustion combined cycle (SCOC-CC) with net power output around 108 MW. The paper describes not only the power balance and the performance of the SCOC-CC, but also the conceptual design of the SCOC turbine and compressor. A model has been built in the commercial heat and mass balance code IPSEpro to estimate the efficiency of semi-
Context: Systems of systems (SoS) are highly complex and are integrated on multiple levels (unit, component, system, system of systems). Many of the characteristics of SoS (such as operational and managerial independence, integration of system into system of systems, SoS comprised of complex systems) make their development and testing challenging. Contribution: This paper provides an understanding
Please cite this paper as: Källén B, Finnström O, Lindam A, Nilsson E, Nygren K-G, Otterblad Olausson P. Selected neonatal outcomes in dizygotic twins after IVF versus non-IVF pregnancies. BJOG 2010; Objective To compare neonatal outcome among twins conceived after in vitro fertilisation (IVF) with that of spontaneously conceived twins. Design Comparison of different-sex (dizygotic) twins born aft
Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). Higher proportions of free PSA (PSA-F/T) in blood are found in subjects with benign prostatic hyperplasia (BPH) as compared to cancer patients. Utilizing imm
This dissertation is an analysis of the culture and lifestyle of women in the middle classes in small towns in southern Sweden between 1790 and 1870, from a gender perspective. The study builds on local material from Lund, Karlshamn and Kristianstad, and is principally made up of the private letters and diaries of a large number of people. The thesis attempts to shed light on relationships, values
Popular Abstract in Swedish Våtmarker är en naturtyp som man finner i övergångszoner mellan land och vatten. Idag talas det mycket om våtmarkers positiva natur- och miljövärden i avrinningsområden i det moderna jordbrukslandskapet. Våtmarker ger omväxling i landskapet och är viktiga biotoper för växter och djur. I våtmarker ansamlas mycket dött växtmaterial och tillsammans med en god tillgång på vIn this thesis, I have studied nitrogen turnover processes in watermeadows. A watermeadow is a wetland where water infiltrates through the soil of a grassland field. It is hypothesized that infiltration of water through the soil matrix promotes nutrient transformations compared to surface flow of water, by increasing the contact between water, nutrients, soil organic matter and bacteria. I have st
To investigate why human immunodeficiency virus type 2 (HIV-2) is less virulent than HIV-1, the evolution of coreceptor usage, autologous neutralization, envelope sequence and glycosylation was studied in sequentially obtained virus isolates and sera from four HIV-2-infected individuals. Neutralization of primary HIV-2 isolates was tested by a cell line-based assay and IgG purified from patients'
OBJECTIVE: To investigate possible associations between use of cardiovascular drugs and suicide. DESIGN: Cross sectional ecological study based on rates of use of eight cardiovascular drug groups by outpatients. A population based cohort study including users of drugs to control hypertension. SUBJECTS: The ecological study included 152 of Sweden's 284 municipalities. The cohort study included all
Time domain reflectometry (TDR) is a widely used method for measuring the dielectric constant (K-a) and bulk electrical conductivity (sigma(a)) in soils. The TDR measured sigma(a) and K-a can be used to calculate the soil solution electrical conductivity, sigma(w.) The sigma(w), in turn, can be related to the concentration of an ionic tracer. Several models of the sigma(w)-sigma(a)-K-a relationshi
Popular Abstract in Swedish Varje år insjuknar ungefär 450 000 kvinnor i livmoderhalscancer (cervixcancer) i världen. Som en följd av screening för livmoderhalscancer, där kvinnor testar sig regelbundet för cellförändringar, har insjuknandet i livmoderhalscancer minskat. Det cellprov som används i screeningen lyckas dock inte upptäcka alla kvinnor som har ökad risk för framtida cancer. Humant papiDifferent types of human papillomavirus (HPV) vary in the extent they cause precursor lesions (CIN) and cancer. There are limited long-term efficacy data on HPV testing in primary screening Among 72 cervical cancers in Mozambique, HPV 16 and 18 were the most frequent HPV types (69% of cases). Comparing 108 cervical cancers cases and 517 matched controls nested within a population-based cohort in
Popular Abstract in Swedish Basic Fibroblast Growth Factor (bFGF) är en av flera tillväxtfaktorer som finns lagrad i benvävnaden. bFGF framkallar celldelning och tillväxt hos många olika celltyper, däribland benceller (osteoblaster) och broskceller. bFGF kan stimulera till nybildning av blodkärl och även benvävnad. I denna avhandling undersökes om utifrån tillfört bFGF kan öka benbildning och vävnBasic Fibroblast Growth Factor (bFGF) is one of the endogenous factors found in bone matrix. bFGF is a mitogen for many cell types, including osteoblasts and chondrocytes. It can stimulate angiogenesis and osteoblast gene expression. The purpose of this study was to investigate whether exogenous bFGF can stimulate the formation of bone in bone grafts and in a bone graft substitute. All experiments
Emerging lines of evidence indicate that the cutaneous human papillomavirus (HPV) types that belong to the genus Betapapillomavirus (beta HPV) are involved in the development of nonmelanoma skin cancer. Unlike the situation for mucosal HPV types, highly sensitive and reliable methods to identify characterized cutaneous HPV types in a single assay are limited. Here, we describe a novel one-shot met
Viruses are ubiquitous in all environments where life is present, also in aquatic environments. The fish-pathogenic virus, Infectious pancreatic necrosis virus (IPNV), has generally been studied because it causes high mortality amongst hatchery-reared salmonids in aqua culture facilities around the world. Today, no efficient vaccine is available to protect the fish from becoming infected. The vir
Trafikbrottslagens 5 § ålägger alla trafikanter, som är inblandade i en trafikolycka, att stanna kvar på platsen för olyckan och lämna upplysningar om händelsen. Uppsatsen undersöker om denna upplysningsplikt kan strida mot Europakonventionens sjätte artikel och skyddet mot självinkriminering, som innebär att en misstänkt person aldrig ska behöva bidra till utredningen om sin egen brottslighet. EuSection 5 of the Swedish Traffic Crimes Act, requires all persons involved in a traffic accident to remain at the scene of the accident and provide information about the incident. This essay examines whether the obligation to disclose certain information about the incident, may violate the sixth article of the European Convention on human rights and the protection against self-incrimination. Accor
I Sverige möts vi allt oftare av rubriker om organisationer som hamnat i blåsväder på grund av o lämpliga uttalanden, kränkande reklam eller oetiskt handlande. Dessa firestorms, som ofta uppstår utan förvarning på nätet, medför stora utmaningar för organisationers marknadskommunikationsavdelningar. Denna studie är skriven inom fältet för kriskommunikation och har ämnat att studera dynamiken inom sIn Sweden, we increasingly face headlines where organizations are accused of inappropriate statements, offending ads and unethical actions. These firestorms, which emerge without any warnings, cause major challenges for organizations’ marketing communication. This thesis is written within the field of crisis communication, with an aim to study the dynamics of different Swedish paracrises. The rese
