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ATP-sensitive K(+) channels (K(ATP) channels) of pancreatic beta-cells play key roles in glucose-stimulated insulin secretion by linking metabolic signals to cell excitability. Membrane phosphoinositides, in particular phosphatidylinositol 4,5-bisphosphates (PIP(2)), stimulate K(ATP) channels and decrease channel sensitivity to ATP inhibition; as such, they have been postulated as critical regulat
BACKGROUND: Indications for implantable cardioverter defibrillator (ICD) implantation have expanded considerably in recent years, resulting in steadily growing numbers of ICD recipients worldwide. The aim of this study was to review the overall experience with ICDs in Iceland. METHODS: This was a retrospective single centre study set at the University Hospital in Iceland. Data on all ICD implantat
A comparative analysis of the electron-hole (e-h) excitation mechanism of impurity luminescence has been performed for wide-gap oxides (WGO) and alkali halides crystals (AHC). A low quantum yield of scintillation in WGO with respect to that in AHC is connected with the high value of the average energy needed for the creation of an e-h pair in WGO. In AHC and many WGO, the width of a valence band E
BACKGROUND: Patients with inflammatory joint diseases tend due to new treatments to be more physically active; something not taken into account by currently used outcome measures. The Rheumatoid and Arthritis Outcome Score (RAOS) is an adaptation of the Knee injury and Osteoarthritis Outcome Score (KOOS) and evaluates functional limitations of importance to physically active people with inflammato
In the last decades, the growing competitiveness of the market has continuously driven the forming companies to highly optimize their products regarding offered performance at minimum cost. In order to achieve better products, studies where conducted with different material models when simulating the forming process of titanium. The material is often used in heat exchanger applications. Titanium h
In this Licentiate Dissertation presents a new model for selecting environmental performance indicators in order to improve environmental management. The suggested Total Cost Indicators support a support a preventive approach to environmental management, where environmental issues are addressed before they arise - and before they become costs. The method of selecting indicators builds on earlie
Vehicles in the future are anticipated to have the ability to communicate and exchange useful information in order to avoid collisions. However, for this cooperation to be possible all vehicles will have to be equipped with compatible wireless IEEE 802.11p modules that implement intelligent transport systems operating in the 5 GHz frequency band standard (ITS-G5 or WAVE). During the implementation
Climate change and disasters are among today’s most pressing issues. The damage caused by the world-wide increase in disasters is staggering, with the urban poor being most at risk. Disasters make their al-ready precarious living conditions worse, creating a vicious circle of poverty. More and more attention has thus been given to the need to address changing climatic conditions and disaster risk
This article was given as a paper at the conference on Deification/Theosis at Drew University, Madison, N.J. in May 2004. The article adresses the growing interest in deification/theosis in contemporary Western theology. Recent research on deification/theosis in Luther and Thomas Aquinas are critically evaluated. The article ends with a proposal. For the better understanding of similarities and di
The concepts of ‘transparency’ and ‘evidence of what works’ are key features in the implementation and success of the open public service policy. This paper explores, from the perspective of the third sector, the meaning of these concepts and how we can expect them to be operationalized. Initially, an implementation guided by evidence and transparency seems reasonable and ethical. The practical me
This report describes the work carried out within the research project ``Merging Real-Time and Control Theory for Improving the Performance of Embedded Control Systems''. The overall objective of the work has been to develop integrated control and scheduling methods for improving the performance of real-time control systems with limited resources. The work has fallen into three categories. First,
This paper presents a hybrid interconnect network consisting of a local network with dedicated wires and a global hierarchical network. A distributed memory approach enables the possibility to use generic memory banks as routing buffers, simplifies the implementation and reduces the area requirements of routers. A SystemC simulation environment (SCENIC) has been developed to simulate and instrumen
