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Development of molecular markers that help to identify high-risk individuals or diagnose indeterminate pulmonary nodules could have a major impact on lung cancer clinical management. In this study, we evaluated the diagnostic potential of a newly-developed ELISA that specifically detects complement C4d. We measured this marker in five independent cohorts of plasma and bronchoalveolar lavage sample

J Thromb Haemostas 2009;7(Suppl2):abstract 672. DOI: 10.1111/j.1538-7836.2009.03473_2.x

Resilience is a debated concept with numerous definitions. If focusing on describing a community under stress of a particular disruptive event, its more traditional etymological meaning of ability to spring back after deformation, or its more applied meaning of ability to cope with and recover from the event, are sufficient. However, if focusing on building and maintaining resilient communities ov

IMPORTANCE Although spouses strongly resemble one another in their risk for alcohol use disorder (AUD), the causes of this association remain unclear. OBJECTIVES To examine longitudinally, in first marriages, the association of a first registration for AUD in one spouse with risk of registration in his or her partner and to explore changes in the risk for AUD registration in individuals with multi

Objectives: Gallstone disease (cholelithiasis) has a familial component, but detailed data on the modification of familial risk are lacking. Using nationwide hospital and population records, we aimed to determine detailed familial risks for medically diagnosed gallstone disease.Design: Subjects were obtained from the Multigeneration Register, which contains family data on the Swedish population, a

The typical approach for archaeological analysis is mainly qualitative and, as such, subjective. Even when some measures are reported in the documentation of artefacts, they are often approximate or ambiguous. Conversely, the quantitative approach is based on objective metrics to produce replicable results and, coupled with digital tools, can assist the qualitative analysis in archaeological resea

With the arrival of heterogeneous manycores comprising various features to support task, data and instruction-level parallelism, developing applications that take full advantage of the hardware parallel features has become a major challenge. In this paper, we present an extension to our CAL compilation framework (CAL2Many) that supports data parallelism in the CAL Actor Language. Our compilation f

Lipids have been implicated in beta-cell stimulus-secretion coupling. In such a role, lipases in beta-cells would be required to generate lipid coupling factors. We have shown previously that glucose stimulates lipolysis in rodent islets. In addition, lipolysis and diacylglycerol lipase activity in islets are abolished by orlistat, an irreversible lipase inhibitor with a broad specificity for subs

The Lorentzian lifetime widths of the 4d and 4f levels in the sixth-period elements W74 to Bi83 have been measured using photoelectron spectroscopy. A compilation of 4f-level widths from the literature is also made. The general trend of the 4f-level widths is well reproduced by McGuires calculations, although the absolute widths seem to be underestimated. The 4d5/2-level width shows a remarkable c

Time-resolved experimental techniques are increasingly abundant at storage ring facilities. Recent developments in accelerator technology and beamline instrumentation allow for simultaneous operation of high-intensity and timing-based experiments. The MAX IV facility is a state-of-the-art synchrotron light source in Lund, Sweden, that will come into operation in 2016. As many storage ring faciliti

We analyze the finite size effects for the source method in pure lattice gauge theory at weak coupling. They are found to be strongly suppressed by twisting the boundary conditions, for SU(3) by typically an order of magnitude.

Using synchronized rapid video imaging and calibrated acoustic emission (AE) measurements, a direct correspondence is found between the length of emerging twin and its AE transient response during in-situ testing of Mg polycrystals. The detectability limit for twin nucleation in Mg and its alloys is evaluated to be as small as 0.3 µm or even less. It is shown that the use of appropriate calibratio

This article examines how a firm's willingness to make trade-offs that favour sustainability over commercial goals attenuates the relationship between firm-level sustainability orientation and subsequent performance. The hypothesis development draws on stakeholder theory and the literature on mission and revenue drifts, while the empirical analysis is based on two waves of original survey data on

This chapter aims to offer insights into the wider implications for the rule of law, including for the EU constitutional order, of the restrictions of migrants’ and asylum-seeker’ rights that follow from systematic noncompliance with the Common European Asylum System (CEAS) by certain Member States. In other words, has the migration and asylum crisis developed into an EU constitutional crisis? Th

The Advanced Normalizations Tools ecosystem, known as ANTsX, consists of multiple open-source software libraries which house top-performing algorithms used worldwide by scientific and research communities for processing and analyzing biological and medical imaging data. The base software library, ANTs, is built upon, and contributes to, the NIH-sponsored Insight Toolkit. Founded in 2008 with the h