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Objective. Lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) are a common condition in men, and their incidence increases with age. The objective of this study was to evaluate the potential cost-utility of microwave thermotherapy, specifically the ProstaLund Feedback Treatment (PLFT), versus alpha-blockade in Swedish patients with LUTS due to BPH. Material and methods.
Wegener granulomatosis (WG) and microscopic polyangiitis (MP), diseases associated with antineutrophil cytoplasmic antibodies (ANCA), had an extremely poor prognosis before the introduction of cyclophosphamide and corticosteroids for their treatment. However, there is still reduced patient survival, and some studies have documented severe side effects of the immunosuppressants used. This 10-yr fol
Background: Risks that are potentially associated with long-term therapies should be assessed. Objective: The present analyses were performed to determine the risk of malignancy in patients with multiple sclerosis (MS) receiving subcutaneous (sc) interferon (IFN) beta-1a, using pooled safety data from key clinical trials and data from the Merck Serono Global Drug Safety database. Methods: The stan
This paper studies contextual effects on fertility at the onset of fertility decline in Sweden. We argue that the community exerts an influence on fertility when individuals belonging to a certain community are more similar to one another (within-area) in their reproductive behaviour than individuals living in another community (between-area). Our hypotheses are that community had a strong influen
Transcription factors encoded by different members of the MADS-box gene family have evolved central roles in the regulation of reproductive organ development in the flowering plants, the angiosperms. Development of the stamens and carpels, the pollen- and seed-bearing organs, involves the B- and C-organ-identity MADS-box genes. B- and C-type gene orthologs with activities specifically in developin
BACKGROUND: In patients with atrial septal defect (ASD) the P-wave is prolonged as a marker of delayed atrial conduction which is associated with atrial fibrillation. The study aim was to analyse the impact of ASD closure in adults on P-wave duration and morphology by means of signal-averaged P-waves (PSA-ECG) and to investigate potential mechano-electrical interactions. METHODS: PSA-ECG was obtai
Recent randomised trials have demonstrated a survival benefit for a front-line ipilimumab and nivolumab combination therapy, and pembrolizumab and axitinib combination therapy in metastatic clear-cell renal cell carcinoma. The European Association of Urology Guidelines Panel has updated its recommendations based on these studies. Patient summary: Pembrolizumab plus axitinib is a new standard of ca
Background: To evaluate the psychosocial consequences of surveillance with whole-body MRI (WB-MRI) in individuals with the heritable TP53-related cancer (hTP53rc) syndrome, also known as the Li-Fraumeni syndrome, with regard to cancer worry, perceived benefits and risks to surveillance and overall health. Patients and methods: Since 2016, the national Swedish TP53 Study (SWEP53) has offered survei
Current consumption patterns are not sustainable and are compromising the Earth’s carrying capacity and the future of next generations. Increasing sustainable consumption behaviours and practices are needed in order to decrease nowadays negative consumption impacts on the environment and achieve sustainable development. However, sustainable consumption practices are generally not performed as they
Two prospective, short-term and long-term consecutive randomized studies on non-surgical treated patients with an ACL injury were performed. None of the patients were athletes on a professional level. Outcome measures : isometric muscle strength and isokinetic musclefunction, one-leg hop test, single limb balance, Lysholm knee score and Tegner activity level. In study number one 26 patients with n
The epitome of this article is the reflection upon the question of “How long is now?” This question is interpreted within the context of the Iraq war, 2003 and onwards, as the enduring now specified. Drawing on parallels from the European World War II experience and the use of “Auschwitz” as a metaphor for a specifically Christian guilt articulated in relation to the Pauline eschatological hope of
This thesis examines the asymmetries between the European Union’s approach to climate justice through the Loss and Damage mechanism and its engagement with cultural restitution. It aims to determine whether and why the EU applies principles of justice differently in these two areas and whether the principles around cultural restitution can inform a more equitable climate justice agenda. With
The taxation of the digital economy has become a relevant subject, as business models and value creation chains of all sectors have been transformed bringing challenges to the international tax system and parameters for the allocation of taxing rights between source and residence jurisdictions. In view of these changes, the European Commission has published two proposals for directives on the taxa
The complexity and dynamicity of microservice architectures in cloud environments present substantial challenges to the reliability and availability of the services built on these architectures. Therefore, effective anomaly detection is crucial to prevent impending failures and resolve them promptly. Distributed data analysis techniques based on machine learning (ML) have recently gained attention
The "International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates-2024" updates and replaces the "Listing Criteria for Heart Transplantation: International Society for Heart and Lung Transplantation Guidelines for the Care of Cardiac Transplant Candidates-2006" and the "2016 International Society for Heart Lung Transplantation Lis
Objective To determine if familial diabetes burden across multiple kinship levels is associated with hospital-diagnosed COVID-19 in a population-based cohort. Methods We analyzed data from 15,516 participants in the Malmö Diet and Cancer Study (MDCS), a prospective, population-based cohort in southern Sweden. Familial burdens among first-degree relatives (parents, siblings, children) of diabetes,
