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Prophylaxis is defined as the regular administration of clotting factor concentrates to prevent bleeding. Extensive data from observational studies and a recent randomized controlled trial (have established that early prophylactic treatment prevents bleeds and arthropathy in boys with severe haemophilia. The initiation of prophylaxis in young children remains challenging. To prevent arthropathy, p
The “acidic mantle” of the skin surface has been related to several essential functions of the skin, although the origin of the acidity is still obscure. In this paper, we investigate how different transport processes can influence the local proton concentration inside a membrane consisting of oriented lipid bilayers. This system is chosen as a simple model of the extracellular lipids in the upper
The ionization sensor is an electrical probe for diagnostics in internal combustion engines. Laser-induced fluorescence (LIF) imaging of fuel, hydroxyl (OH), and nitric oxide (NO) distributions has been employed to extend our knowledge about the governing processes leading to its signal. By monitoring the flame propagation in quiescent and turbulent mixtures, the cycle-to-cycle variations in the e
In several twin studies the relative contribution of genetic factors for personality traits has amounted to figures between 40 and 60%. In the present study we investigated to which degree polymorphisms in the 5-HTT and AP-2 beta genes are implicated in the neural processes involved in the formation of Temperament and Character traits, as estimated by Cloninger's TCI. Considering the background of
Currently in Europe as well as in the United States, an increasing proportion of very old people remain living in their homes despite declines in physical and mental health. Together with the fact that the population of very old people is rapidly increasing (Mathers, Sadana, Salamon, Murray, Lopez, 2001; United Nations Development Programme, 2001), this poses new challenges to societal planning an
A model for a special configuration in triaxial odd-odd nuclei is constructed which exhibits degenerate chiral bands with a sizable rotation, a manifestation of dynamical spontaneous symmetry breaking. A quantum number obtained from the invariance of the model Hamiltonian, which characterizes observable states, is given and selection rules for electromagnetic transition probabilities in chiral ban
The overall aim of the chapter is to reflect a classroom project on creative learning processes by four “dialogues” between researcher and teacher perspectives on a sequence of themes that lead up to the morale of the tale; Computers and learning, Creativity and education, Creative teaching and Creative learning.
This study is motivated by the need to know the characteristics of the learning processes in tongue-computer interaction and to obtain a useful insight to a better design of the tongue-computer interface for computer text input. Tongue-typing can be a good alternative to hand input methods for physically disabled individuals or tasks where hand-typing is not possible. In order to evaluate the proc
Child mortality because of infectious preventable diseases is a global tragedy. Millions of children die in vain every year. This thesis presents a sincere effort to decrease child mortality on given reason. The servitized Business Information System (BIS) named VacSam provides unique vaccination recommendations to any child thus service orienting a part of the Swedish vaccination activity. Design
A control point for keeping redox homeostasis in Saccharomyces cerevisiae during fermentative growth is the dynamic regulation of transcription for the glycerol-3-phosphate dehydrogenase 2 (GPD2) gene. In this study, the possibility to steer the activity of the GPD2 promoter was investigated by placing it in strains with different ability to reoxidise NADH, and applying different environmental con
Tools for accurate measurements of microbial biomass/abundance are imperative in soil ecology. This perspective was prompted by a lack of consistency in how the neutral lipid fatty acid (NLFA) and phospholipid fatty acid (PLFA) 16:1ω5 are used to estimate arbuscular mycorrhizal (AM) fungal abundance, which we argue can lead to erroneous conclusions within studies and complicate among-study compari
The majority of all environmental impacts can be linked to our consumption. As real wages increase, so does consumption levels – more holiday trips, more clothing purchases, faster replacement of products for newer versions,etc. This trend poses a threat to the state of our planet. While the Nordic countries are high in the overall rankings of achieving the UN’s Sustainable Development Goals, they
We report on measurements of a charge-dependent flow using a novel three-particle correlator with ALICE in Pb-Pb collisions at the CERN Large Hadron Collider (LHC), and discuss the implications for observation of local parity violation and the chiral magnetic wave (CMW) in heavy-ion collisions. Charge-dependent flow is reported for different collision centralities as a function of the event charge
This thesis is a study of Twelver Shi’a Islam in the context of Azeri-Turkish Muslims living in the Anatolia-Caucasus borderlands of Northeastern Turkey. Taking the sonic as the central focus and field of enquiry I listen to the ways that sound mediates between bodies, both somatic and social, and the divine in the ritual and quotidian lives of Shi’i practitioners. I argue that sound, voice and li
In the challenge to reduce CO2, NOx and PM emissions, the application of natural gas or biogas in engines is a viable approach. In heavy duty and marine, either a conventional dual fuel (CDF), or a reactivity-controlled compression ignition (RCCI) approach is feasible on existing diesel engines. In both technologies a pilot diesel injection is used to ignite the premixed natural gas. However, the
