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A species-wide phylogeographical study of the root vole (Microtus oeconomus ) was performed using the whole 1140 base pair mitochondrial (mt) cytochrome b gene. We examined 83 specimens from 52 localities resulting in 65 unique haplotypes. Our results demonstrate that the root vole is divided into four main mtDNA phylogenetic lineages that seem to have largely allopatric distributions. Net diverge
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Collagen induced arthritis (CIA) is a common mouse model for rheumatoid arthritis. Two sets of truncated peptides derived from type II collagen have been prepared and tested for binding to A(q), a MHC-II molecule associated with development of CIA. Binding to A(q) correlated well with predictions from a computer-based model. T-cell hybridomas, obtained in CIA, were also used to study the ability o
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Although the Normalized Difference Vegetation Index (NDVI) time-series data, derived from NOAA/AVFIRR, SPOT/VEGETATION, TERRA or AQUA/MODIS, has been successfully used in research regarding global environmental change, residual noise in the NDVI time-series data, even after applying strict pre-processing, impedes further analysis and risks generating erroneous results. Based on the assumptions tha
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The formation of inhibitory alloantibodies is, in the postinfectious era, the most severe and costly complication of replacement therapy in patients with haemophilia. The complexity of the immune response to the infused factor becomes more and more obvious as knowledge in the area increases. Antibodies develop as a result of a complex multi-factorial interaction between antigen-presenting cells, T
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Fifteen polymorphic markers were developed from a microsatellite-enriched library for the lizard Podarcis gaigeae. The loci were checked for variability in 68 individuals from a population on the island of Skyros, Greece. The number of alleles ranged from 3 to 23 per locus and expected heterozygosity from 0.29 and 0.94. Most markers were also polymorphic in three closely related Podarcis species,
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This paper presents the coupled cluster/molecular mechanics (CC/MM) and self-consistent field/molecular mechanics (SCF/MM) approaches for wavefunctions, energies and response properties. Two physically different theories are derived, the mean-field and the direct-field interaction approaches, together with expressions for the optimization condition of both variational and non-variational wavefunct
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Aims/hypothesis Post-translational modifications, such as isomerisation of native proteins, may create new antigenic epitopes and play a role in the development of the autoimmune response. Protein-L-isoaspartate (D-aspartate) O-methyltransferase (PIMT), encoded by the gene PCMT1, is an enzyme that recognises and repairs isomerised Asn and Asp residues in proteins. The aim of this study was to asse
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BACKGROUND: The purpose of this study was to analyze the impact of stent-graft design and operator skills on outcomes after endovascular abdominal aortic aneurysm repair. STUDY DESIGN: One hundred sixty-four patients (mean age 71 years) underwent stent-graft repair. Patients were treated with four different types of stent-graft: first-generation (n = 58) and second-generation (n = 17) Ivancev-Malm
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Public procurement and the purchasing of goods, services and works comprises about 14% of the European gross domestic product (GDP). Procurement initiatives, guidance and tools therefore can have significant influence to leverage demands for more sustainable and circular products and services. This study explores the current circular public procurement (CPP) landscape, looking at barriers and oppo
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Uppsatsen är baserad på två hovrättsdomar angående internetavstängningar i Indien med en systematisk innehållsanalys av rättsliga yttranden och en teori om yttrandefrihet i informationssamhället. Syftet med studien är att förstå resonemangen från domarna kring implementeringen av lagarna, både i de två utvalda domsluten och domarnas tolkning av yttrandefriheten och rätten till personlig frihet. De
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The thesis explores online knowledge production around a subject that has been considered taboo and inappropriate through history – sexual, reproductive and genital health for people with female genitals. Therefore, it also examines the political potential of coming together to openly discuss such “delicate issues”. The focus of the study is the Swedish Facebook-group “Fittlife – underliv och häls
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Power systems operate at a specific frequency and constantly require a balance between production and consumption of electricity in order to maintain the frequency within a certain interval. Larger frequency deviations can cause blackouts or damage equipment connected to the grid. Balancing functions that stabilise the grid are referred to as \textit{ancillary services}, which in Sweden include th
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Som en följd av EU-beslutet om ett nettonollutsläppsmål till 2050 har flera industrier utvecklat färdplaner för hur dessa utsläppsminskningar ska uppnås. Det här examensarbetet undersöker kemiindustrins färdplaner i syfte att bedöma hur de ser på sin roll i att nå EU:s utsläppsmål. Teknikerna och strategierna som används i färdplanerna för att nå utsläppsminskningar varierar stort. Ofta antas att Following the decision set by the EU of a net-zero greenhouse gas emission target for 2050, several industries have made roadmaps for how these reductions will be achieved. This thesis investigates the chemical industry roadmaps in order to assess how they envision their role in reaching the EU target. The technologies and strategies used in the roadmaps to reach the reduction targets vary widely,
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The aim of this project is to establish a workflow that transforms CT-scanned images of paperboard into a calibrated Representative Volume Element (RVE). A RVE is defined as the smallest volume that accurately captures the macroscopic behaviour of the material. First, CT-scanned images are converted into a finite element model that rep- resents the microstructure of the paperboard. Secondly, a di
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Bioacoustic sound event detection (SED) is a critical field for biodiversity monitoring, yet the high cost of annotating data poses significant challenges. This thesis explores the application of active learning strategies to reduce the amount of annotated data required for effective model training. This is done for a segment based SED model, where batch active learning is performed by querying fu
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The need for speed in communications systems is increasingly prevalent in modern society, which is one of the driving factors for the evolution of new technologies. At the forefront of this evolution are Multiple-input Multiple-output (MIMO) systems. Through the usage of many antennas at the base station (BS) and user equipment (UE), significantly enhances the potential maximum data transfer rates
