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Vertebral fractures are often painful and lead to reduced quality of life and disability. We compared the efficacy and safety of balloon kyphoplasty to nonsurgical therapy over 24 months in patients with acute painful fractures. Adults with one to three vertebral fractures were randomized within 3 months from onset of pain to undergo kyphoplasty (n = 149) or nonsurgical therapy (n = 151). Quality
The aim of this paper is to make it credible that there are feminist reasons for being a republican about freedom. In focus is Quentin Skinner’s conception of republican, or “neo-Roman”, freedom. Republican theory in history has not excelled in making poverty, gender hierarchy, and racism within the republic into main sources of concern. So can there be a radical republican theory of liberty fit f
Hyperthermia is a frequent complication in patients with acute ischemic stroke. On the other hand, therapeutically induced hypothermia has shown promising potential in animal models of focal cerebral ischemia. This Guideline Document presents the European Stroke Organisation guidelines for the management of temperature in patients with acute ischemic stroke.
Understanding, monitoring and mitigating drought is a very difficult task as a consequence of the intrinsic nature of the phenomenon. In addition, assessing the impact of drought on ecosystems and societies is also a complex task, because the same drought severity may have different consequences in different regions and systems due to the underlying vulnerabilities. New technologies based on geosp
CONTEXT: Prior research suggests that drug abuse (DA) is strongly influenced by both genetic and familial environmental factors. No large-scale adoption study has previously attempted to verify and integrate these findings. OBJECTIVE: To determine how genetic and environmental factors contribute to the risk for DA. DESIGN: Follow-up in 9 public databases (1961-2009) of adopted children and their
Data from four soil profiles studied through pollen and macroscopic charcoal analyses were used to identify specific palynological assemblages associated with a traditional land-use system documented in the Eastern Ligurian Apennines (NW Italy) between the 18th and early 20th century, concerning a cyclical use of grey alder plots for temporary cultivations involving to the use of controlled fire.
Patients with depression and suicidality suffer from low-grade neuroinflammation. Pro-inflammatory cytokines activate indoleamine 2,3-dioxygenase, an initial enzyme of the kynurenine pathway. This pathway produces neuroactive metabolites, including quinolinic- and kynurenic acid, binding to the glutamate N-methyl-d-aspartate-receptor, which is hypothesized to be part of the neural mechanisms under
Objective The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of SLE. Methods The classification criteria were derived from
The Minnesota Heart Health Program was a community trial of cardiovascular disease prevention methods that was conducted from 1980 to 1990 in three Upper Midwestern communities with three matched comparison communities. A 5- to 6-year intervention program used community-wide and individual health education in an attempt to decrease population risk. A major hypothesis was that the incidence of vali
The use of a label for locally produced products is seen as a good way of promoting these products in Söderslätt and, thereby, promoting regional development. The only common meaning of the concept ?local? is the reference to a geographical area, even though the size of the area differs. Local products are associated with characteristics such as environment, ethics, health, quality and support of
This master thesis presents a qualitative model for performing a due diligence analysis of non- financial risks and their management, the DANFiRM model. The model includes a thinking process and a working procedure for identifying and evaluating the current non-financial risk exposure at the target enterprise and further required measures for altering risk exposure and risk management activities t
Metals play a key role as a cornerstone of our modern society; they are part of the most basic elements of our daily life and have been part of our lifestyles for millennia. Current trends of metal production point out that developing countries in order to attain a developed-countries consumption level will require 3-9 times the present metal stock per capita, yet their mining practices are far fr
Countries around the world are employing renewable energy policies to increase renewable electricity in their electricity mix. Trinidad and Tobago (T&T), located in the Caribbean, has endogenous sources of oil and natural gas and has not yet capitalised on sources of renewable energy. The country‟s electricity is currently dominantly generated from natural gas however the natural gas reserves
Det här examensarbetet ger en översikt över organiskt material (kerogen) i Jordens yngre lagrade berggrund och hur detta material omvandlats till olja och naturgas genom olika geologiska processer. De viktigaste är tryck, temperatur och tid. Med fortskridande sedimentpålagring förs det organiskt rika sedimenten successivt ned på större djup, där de genomgår en så kallad mognadsprocess till följd aThe origin, composition and maturity of kerogen, and its conversion to petroleum is reviewed. Various methods for estimating the maximum temperature to which kerogen and potential source rocks were subjected are also reviewed. Several kerogen maturation parameters can be distinguished and grouped into two categories: chemical paleothermometres and biological paleothermometres. Biological paleother
During evolution the human brain has increased drastically in size compared to that of other primates. However, little is known about primate brain development as it is difficult to study human and primate brains in the laboratory due to the scarcity of tissues. Yet, it is essential to study primate brains and understand the molecular features leading to the human brain’s unique cognitive function
By the end of the 1960s there was a growing environmental concern all around the globe. As a part of an answer to this challenge the need was recognized for a reorientation of the education processes towards developing knowledge, attitudes and skills for resolving the issues. This was the birth of the concept of Environmental Education (EE). However, this notion is far from being static as it went
Purpose of study: As both innovations and brand loyalty are becoming ever more important for companies today, it is of importance to understand how an organisation can handle the relationship between the explorative and exploitative units when working with these two constructs. The ultimate aim is to understand how service organisations can be managed in order to enhance brand loyalty through serv
