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Purpose: The majority of women with ovarian cancer are diagnosed in late stages. Most women do have symptoms prior to diagnosis, sometimes several months before the diagnosis. The aim of this study was to evaluate the timeline from the first presentation of symptoms to a physician until there is a reasonable suspicion of cancer, among women diagnosed with advanced stage ovarian cancer. We wanted t
Introduction: Health problems in people with intellectual and developmental disability (IDD) are traditionally known to be common in adults of all age, with at least twice as many health problems in this group as the general ageing population. In addition, there is considerable international evidence indicating an earlier death for people with IDD compared to the general population, exacerbated by
Modern microbial and ecosystem sciences require diverse interdisciplinary teams that are often challenged in “speaking” to one another due to different languages and data product types. Here we introduce the IsoGenie Database (IsoGenieDB; https://isogenie-db.asc.Ohio-state.edu/), a de novo developed data management and exploration platform, as a solution to this challenge of accurately representin
Introducing seaweed to new food markets entails new challenges concerning efficient preservation. Hence, this study explores high-pressure processing (HPP) as an alternative technique to conventional methods by evaluating its effects on the composition, quality, and microbial safety of the Swedish grown macroalgae Saccharina latissima. The results from the physicochemical analysis showed that afte
On 5 January 2023, the Swedish Government announced the decision to introduce new restrictions to enter Sweden: due to the spread of Covid-19 in China, travellers from this direction need to show negative Covid-test results. In cases when there is no possibility of showing the results, the travellers are not allowed to enter Sweden. Governmental Ordinance (2023:2) was temporary and lasted from 7 J
Purpose: Adolescents with congenital heart disease transition from childhood to adulthood and transfer from pediatric-oriented to adult-oriented care. High-level empirical evidence on the effectiveness of transitional care is scarce. This study investigated the empowering effect (primary outcome) of a structured person-centered transition program for adolescents with congenital heart disease and s
The paper examines the perceptions of knowledge workers of small-medium enterprises (SMEs) in the Chinese context in regards to managing innovation in their knowledge work with the support of digital technologies. Main concepts such as knowledge, knowledge work, knowledge workers, innovation in knowledge work and digital technologies along with Socialization, Externalization, Combination and Inter
Background: People with inflammatory arthritis often experience challenges at work and balancing paid work and energy in everyday life. Low work ability is common, and people with inflammatory arthritis face high risks of losing their jobs and permanent exclusion from the labour market. Context-specific tailored rehabilitation targeting persons with inflammatory arthritis is limited. The aim of th
Family reunification is, in the words of the European Union (EU) Family Reunification Directive (2003/86/EC), a ‘necessary way of making family life possible’ and preserving family unity. Yet, barriers exist which hinder refugees’ realisation of their right to family reunification. By taking the plight of Eritrean refugees in Europe as a pertinent case study, this paper shows the obstacles that “p
Delayed cerebral ischemia (DCI) occurs in up to one third of patients suffering from aneurysmal subarachnoid hemorrhage (aSAH). Untreated, it leads to secondary cerebral infarctions and is frequently associated with death or severe disability. After aneurysm rupture, erythrocytes in the subarachnoid space lyse and liberate free hemoglobin (Hb), a key driver for the development of DCI. Hemoglobin i
This paper examines corporate angels, small businesses that provide equity capital directly to unquoted ventures and become minority shareholders. Corporate angels have been largely ignored in entrepreneurial finance research. This novel study examines corporate angels' investment practices, goals and challenges by means of a combination of qualitative cases and a survey of 87 corporate angels. Fr
A persistent anthropocentric school of thought prevents comparative cognition from truly joining the evolutionary sciences, which often view “cognition” as an alien subject to the study of life. In this article, I argue that cognition is indeed inherent to all life and that we could study the evolution of cognitive skills like any other species-specific trait if we stop elevating convergence over
Ribosomes trapped on mRNAs during protein synthesis need to be rescued for the cell to survive. The most ubiquitous bacterial ribosome rescue pathway is trans-translation mediated by tmRNA and SmpB. Genetic inactivation of trans-translation can be lethal, unless ribosomes are rescued by ArfA or ArfB alternative rescue factors or the ribosome-associated quality control (RQC) system, which in Bacill
Digital healthcare services and digital health information, here called eHealth services, have the potential to reach people with diverse needs as both a complement to and a substitution for traditional healthcare. The access to and use of digital health information and digital healthcare services that are accessible and usable for people with impairments is a complex phenomenon.This potential is
BACKGROUND: Coronary atherosclerosis detected by imaging is a marker of elevated cardiovascular risk. However, imaging involves large resources and exposure to radiation. The aim was, therefore, to test whether nonimaging data, specifically data that can be self-reported, could be used to identify individuals with moderate to severe coronary atherosclerosis.METHODS AND RESULTS: We used data from t
Contemporary society operates beyond safe boundaries of the Earth system. Returning to a safe operating space for humanity within Earth system boundaries is a question of justice. The relevance of the economy—and thus of business—for bringing society back to a safe and just operating space highlights the importance of business ethics research for understanding the role of business in Earth system
Livscykelanalys (LCA) används för att utvärdera den potentiella miljöpåverkan av olika processer och tjänster, bland annat inom bygg- och fastighetssektorerna. Denna studie jämför tre LCA-verktyg som är speciellt utvecklade för användning inom bygg- och fastighetssektorn mot ett fjärde som är ett allmänt LCA-verktyg. En LCA görs för en fallstudie av ett flerfamiljshus där ett ventilationssystem meLife cycle assessment (LCA) is used to evaluate the potential environmental impact of different processes and services, including in the construction and real estate sectors. This study compares three LCA tools that have been specifically developed for use in the construction and real estate sectors with a fourth that is a general LCA tool. An LCA is performed for a case study of a multi-family bu
IMPORTANCE: Perforated colonic diverticulitis usually requires surgical resection, which is associated with significant morbidity. Cohort studies have suggested that laparoscopic lavage may treat perforated diverticulitis with less morbidity than resection procedures. OBJECTIVE: To compare the outcomes from laparoscopic lavage with those for colon resection for perforated diverticulitis. DESIGN, S
Climate change poses an existential threat to humanity. It is now indisputable that the primary cause of this threat is human activity resulting in high greenhouse gas (GHG) emissions, which began during the Industrial Revolution and have continued to rapidly accelerate. The first warnings of impending and irreversible climate change were sounded decades ago, when governmental and intergovernmenta
