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Purpose: The Oriatron eRT6 is an experimental high dose-per-pulse linear accelerator (linac) which was designed to deliver an electron beam with variable dose-rates, ranging from a few Gy/min up to hundreds of Gy/s. It was built to study the radiobiological effects of high dose-per-pulse/dose-rate electron beam irradiation, in the context of preclinical and cognitive studies. In this work, we repo

Culture and creativity are often described as central elements in urban and regional development. This paper takes its point of departure in an ongoing research project on the work of professionals at platforms for creative and cultural work in Scania, Sweden. Through narratives of and about the professionals at the different platforms the paper illustrates how creativity and creative work are enc

Spectroscopy from the final internal data release of the Gaia-ESO Survey (GES) has been combined with Gaia EDR3 to assign membership probabilities to targets observed towards 63 Galactic open clusters and 7 globular clusters. The membership probabilities are based chiefly on maxim likelihood modelling of the 3D kinematics of the targets, separating them into cluster and field populations. From 43

How many nanoparticles can we load in a fiber? How much will leak? Underlying is the relatively new question of the “space available” in fibers for nanoparticle loading. Here, using supercritical carbon dioxide (scCO2 ) as a carrier fluid, we explored the impregnation in four Indian silks (Mulberry, Eri, Muga, and Tasar) with five standard sizes of gold nanoparticles (5, 20, 50, 100 and 150 nm in

Glomerular filtration rate (GFR) is estimated by creatinine or cystatin C-based GFR-estimating equations. Those based upon creatinine, but not those based upon cystatin C, use ”race” terms due to that different populations differ in average muscular mass, influencing the creatinine, but not the cystatin C, level. “Race” is not a biological, but a sociological term, determined by self-assesment. Ne

In the event of an accidental release of radioactive elements from a nuclear power plant, it has been shown that the radionuclides contributing the most to long-term exposure are 134Cs and 137Cs. In the case of nuclear power plant fallout, with subsequent intake of radionuclides through the food chain, the internal absorbed dose to target tissues from protracted intake of radionuclides needs to be

Background Creating new therapies often involves drug companies paying healthcare professionals and institutions for research and development (R&D) activities, including clinical trials. However, industry sponsorship can create conflicts of interests. We analysed approaches to drug company R&D payment disclosure in European countries and the distribution of R&D payments at the country

We report the first systematic investigation of relativistic effects on the UV-vis spectra of two prototype complexes for so-called photo-activated chemotherapy (PACT), trans-trans-trans-[Pt(N3)2(OH)2(NH3)2] and cis-trans-cis-[Pt(N3)2(OH)2(NH3)2]. In PACT, design of new drugs requires in-depth understanding of the photo-activation mechanisms. A first step is usually to rationalize their UV-vis spe

This paper is based on the work done for the 2017 AIAA Student Design Competition-Human Spaceflight: Phobos Base. One of humanity's major challenges when travelling to Mars is represented by the existence of an atmosphere around the red planet. In fact, even though the Martian atmospheric density is only about 1% of that of Earth, the entry, descent and landing (EDL) procedure for large payloads i

PURPOSE: Epinephrine is used in local anesthetics to induce vasoconstriction and thus reduce bleeding and prolong the anesthetic effect. Finding the optimal delay between the administration of the anesthetic and skin incision to ensure vasoconstriction and minimize bleeding is important and has recently become the subject of debate. This is the first study to assess blood perfusion and oxygen satu

Background: Targeted therapeutic mild hypercapnia may attenuate brain injury in comatose adults resuscitated from out-of-hospital cardiac arrest. Objective: To describe the study protocol and statistical analysis plan for the Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) trial. Design, setting, participants and interventions: TAME is a phase 3, multicentre, paralle

Previous studies have shown that alkali salts influence combustion processes and soot formation, although the effects seem to vary across systems. Moreover, fundamental studies on the effect of potassium and sodium salts on formation of polycyclic aromatic hydrocarbons (PAH), which are precursors in soot formation, are scarce. Here, we report a study in which the effects on PAH formation due to th

OBJECTIVE: Previous literature has suggested that identifying putative differences in health care seeking patterns before death by suicide depending on age and gender may facilitate more targeted suicide preventive approaches. The aim of this study is to map health care utilisation among individuals in the two years prior to suicide in Sweden in 2015 and to examine possible age and gender differen

Marine mammals and coastal fisheries are two features commonly associated with thriving marine environments, but it is also a case of wildlife impact on human interests. This paper analyses the seal-fisheries encounter in a Swedish Baltic Sea fishery. The problem concerns seals eating fish from the fishing gear which causes considerable economic losses to small-scale fishermen. This mixed-method s

BACKGROUND: The objective of the Swedish cleft lip and palate (CLP) registry is to promote quality control, research and improvement of treatment, by comparison of the long-term results of surgery, orthodontics and speech from all six Swedish CLP centres. The purpose of the study was to investigate the coverage and reporting degree of the Swedish CLP registry, and to describe the design of the reg

Objective: Endovascular aneurysm repair (EVAR) has been extensively study regarding elective and ruptured abdominal aortic aneurysm (AAA) repair. However, much less is known about EVAR of symptomatic nonruptured AAA, especially concerning the long-term results. The aim of this study was to assess the outcomes of EVAR of symptomatic AAA compared with asymptomatic AAA at a tertiary center using a si

Mitochondrial dihydroorotate dehydrogenase (DHOdehase; EC 1.3.99.11) is a target of anti-proliferative, immunosuppressive and anti-parasitic agents. Here, redoxal, (2,2'-[3,3'-dimethoxy[1, 1'-biphenyl]-4,4'-diyl)diimino]bis-benzoic acid, was studied with isolated mitochondria and the purified recombinant human and rat enzyme to find out the mode of kinetic interaction with this target. Its pattern