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The performance of HVAC equipment, including chillers, is continuing to be pushed to theoretical limits, which impacts the necessity for advanced control logic to operate them efficiently and robustly. At the same time, their architectures are becoming more complex; many systems have multiple compressors, expansion devices, evaporators, circuits, or other elements that challenge control design and
Innehållet i denna paper är i stort detsamma som i papern publicerad i Philologica Jassyensia 2008, men föredraget vid denna konferens insisterar mer på hur vi har „byggt upp” olika studieaktiviteter i den virtuella miljön för att kunna uppnå en nästintill maximal flexibilitet respektive effektivitet i lärandet.
Introduction: It is well known that urinary tract infection (UTI) during pregnancy is associated with preterm birth, but information about the risk of preterm birth depending on gestational week of infection is sparingly described in the literature. Material and Methods: An observational study based on data from Swedish registers including women giving birth 2014–2020 (n = 684 595). Pregnant women
Bacteria encode diverse defence systems, including restriction-modification and CRISPR-Cas, that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstrate that many recently identified antiphage defence operons comprise a nuclease and NTPase protein, suggesting that additional nucleic acid-targeting systems remain to be understood. Here we develop large-scale compa
Long RSH enzymes, Rel and RelA, are master regulators of bacterial (p)ppGpp alarmones levels. Bifunctional Rel transitions between a compact hydrolysis-competent (HD ON) state, a relaxed catalytically inactive (HD OFF/SYNTH OFF) state, and an elongated synthesis-competent (SYNTH ON) state, whereas RelA samples only the latter two. The distribution of these states is controlled by starved ribos
At Dagsmosse in south-central Sweden, evidence from well-preserved Mesolithic wetland sites (10,200–7000 cal a BP) demonstrates occupation continuity among Hunter-Gatherer-Fisher (HGF) communities in wetland areas. This study presents detailed environmental reconstructions of the Dagsmosse basin, where Mesolithic fishing and dwelling activities were recorded. Focusing on the Preboreal–Boreal biozo
Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research. While capture-recapture methods can estimate unknown case numbers, their role in estimating exposure effects in observational studies is not well established. This paper presents an ascertainment probability weighting framework that integrates
Before curation, there is collection. Before visitors engage with objects in an exhibition, collection managers engage with the objects and, in some cases, also the donors. It makes sense that especially when difficult pasts are involved, collection managers have affective encounters with the materiality before visitors do. So why has the affective turn focused mainly on engaging visitors’ emotion
Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR
Introduction: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. Methods: A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels was performed while accounting for gene-educational attainment inter
This chapter focuses on taxation in Africa since 1900. Using existing data and insights from the literature, the chapter documents taxes collected by colonial and post-colonial states, exploring what was taxed, the types of taxes, the tax revenue patterns and the socio-political contexts shaping taxation policies. It begins by discussing the fundamental principles of taxation and forms of direct a
We evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors. We find abundant allelic heterogeneity, where multiple variants regulate a particular molecular phenotype, and pleiotropy, where a single variant associates with multiple molecular phenotypes over multiple genomic regions. The highest proportion of share genetic re
